Schematic representation of identification and selection of top hits that inhibit viral M mRNA nuclear export and/or expression. by Matthew Esparza (8661219)

“…The top 600 compounds from single-dose confirmation studies were further evaluated in a 12-point dose response study to assess the potency (AC50 –concentration at 50% activity). …”

Data_Sheet_1_An economic analysis of high milk somatic cell counts in dairy cattle in Chiang Mai, Thailand.docx by Tosapol Dejyong (14055744)

“…Dairy cooperatives point at high-SCC problems as an important factor leading to suboptimal levels of milk quantity and quality. …”

Table 1_Inflammation and nutritional status in relation to mortality risk from cardio-cerebrovascular events: evidence from NHANES.docx by Chengzhi Hou (20419865)

“…To the left of this inflection, each unit increase in ALI was associated with a 1.3% decrease in all-cause and cardiovascular mortality risk among MACCE patients. …”

Transcriptome Profiling of the Intoxication Response of <em>Tenebrio molitor</em> Larvae to <em>Bacillus thuringiensis</em> Cry3Aa Protoxin by Brenda Oppert (168488)

“…<div><p><em>Bacillus thuringiensis</em> (Bt) crystal (Cry) proteins are effective against a select number of insect pests, but improvements are needed to increase efficacy and decrease time to mortality for coleopteran pests. …”

Image 1_Inflammation and nutritional status in relation to mortality risk from cardio-cerebrovascular events: evidence from NHANES.tif by Chengzhi Hou (20419865)

“…To the left of this inflection, each unit increase in ALI was associated with a 1.3% decrease in all-cause and cardiovascular mortality risk among MACCE patients. …”

Successful Application of Adaptive Emotion Regulation Skills Predicts the Subsequent Reduction of Depressive Symptom Severity but neither the Reduction of Anxiety nor the Reduction... by Carolin M. Wirtz (647287)

“…</p><p>Results</p><p>Successful ER skills application was cross-sectionally associated with lower levels of DSS, ASS, and GDS at all points of assessment. An increase in successful skills application during treatment was associated with a decrease in DSS and GDS but not ASS. …”

Worm infestations and development of autoimmunity in children – The ABIS study by Johnny Ludvigsson (167260)

“…At 8 years in total 20.0% of the general child population had experienced a worm infestation; children who developed Type 1 diabetes, 21,3%, celiac disease 19,5% and JRA 18,8%. …”

Wind-Driven Ignition Behavior of Wildland Fuels: Experimental Insights Under Controlled Conditions by Shusmita Saha (19162790)

“…For example, in wheatgrass fuels, flaming ignition temperature rose from ~ 472°C to ~ 610°C as wind speed increased from 0.5 to 2.0 m/s, with a concurrent decrease in smoldering-to-flaming transition time from 105 to 61 seconds. …”

Intracellular pH Measurements Using Perfluorocarbon Nanoemulsions by Michael J. Patrick (1872154)

“…In rat 9L glioma cells loaded with nanoemulsion, the local pH of nanoemulsions was longitudinally quantified using optical microscopy and flow cytometry and displayed a steady decrease in pH to a level of 5.5 over 3 h, indicating rapid uptake of nanoemulsion to acidic compartments. …”

SLS-4 is required for the <i>in vitro</i> ubiquitination of poly-SUMO-2 chains and degradation of SUMO conjugates <i>in vivo</i>. by Chris Boutell (205885)

“…<p>(A) <i>In vitro</i> ubiquitination reactions were carried out in the presence of E1, UbcH5a and ubiquitin (Ubmix), poly-SUMO-2 chains and purified wt ICP0, ICP0ΔRING, or ICP0 C-terminal truncation mutants ICP01-323, ICP01-396 or ICP01-396mSLS-4 as indicated (-/+). …”

Impact of loss of <i>Hes1</i> on differentiation and proliferation in the second heart field. by Francesca Rochais (371680)

“…<p>(A) Immunochemistry with anti-MHC (left), anti-α-actinin (right) and anti-β-galactosidase antibodies in transverse sections through the caudal pharyngeal region of an E9.5 embryo carrying the <i>Mlc1v-nlacZ-24</i> transgene. …”

Evaluation of the articular cartilage in the knees of rats with induced arthritis treated with curcumin by Tiago Nicoliche (8566002)

“…Based on the results of this study, the curcumin treatment appeared to exert a protective effect on cartilage, as it did not result in an increase in cartilage thickness or in MMP-8 and MMP-13 expression but led to increased IHH, Col2, and SOX-5 expression and the number of chondrocytes.…”

Intracellular pH Measurements Using Perfluorocarbon Nanoemulsions by Michael J. Patrick (1872154)

“…In rat 9L glioma cells loaded with nanoemulsion, the local pH of nanoemulsions was longitudinally quantified using optical microscopy and flow cytometry and displayed a steady decrease in pH to a level of 5.5 over 3 h, indicating rapid uptake of nanoemulsion to acidic compartments. …”

HSPs Inhibits CKII Mediated TDP-43 Filament Assembly. by Yari Carlomagno (152800)

“…<p>Hsp90 can inhibit the polymerization of tau, and TDP-43 is a known substrate for Hsp90. To examine the effects of Hsp90 on CKII mediated rTDP-43 filament assembly, 2.5 µM TDP-43 was polymerized for 60 minutes with CKII in the presence of 0.0–2.5 µM Hsp90. …”

Table_2_Acute hyperglycemia compromises the responses of choroidal vessels using swept-source optical coherence tomography during dark and light adaptations.docx by Zhiyang Lin (284691)

“…However, only TCV (0.38 ± 0.17 mm³) and LV (0.27 ± 0.10 mm³) showed a significant increase at the time point of 5 min after ambient light.…”

Genomic driver underlies clonal shift of methicillin-resistant <i>Staphylococcus aureus</i> in the healthcare setting by Shuangshuang Li (441516)

“…<p>The epidemiology of healthcare-associated methicillin-resistant <i>Staphylococcus aureus</i> (HA-MRSA) has shifted in recent decades, with a notable decline in the lineage ST239 and continued dominance of ST5. …”

Table_1_Acute hyperglycemia compromises the responses of choroidal vessels using swept-source optical coherence tomography during dark and light adaptations.docx by Zhiyang Lin (284691)

“…However, only TCV (0.38 ± 0.17 mm³) and LV (0.27 ± 0.10 mm³) showed a significant increase at the time point of 5 min after ambient light.…”

Double knockdown of <i>Gli1/Gli2</i> in XY gonads. by Kathryn S. McClelland (687254)

“…<p>(A–D) Knockdown of GLI1/GLI2 in the gonad: qRT-PCR showed that treatment with Gli1/Gli2MO (<i>n</i> = 6, 5, 5, 8) resulted in no significant downregulation in steroidogenic regulator <i>Sf1/Nr5a1</i> (A) but a significant downregulation in expression of steroidogenic pathway enzymes <i>Hsd3β</i> (B), <i>Cyp11a1</i> (C) and <i>Star</i> (D). …”

DataSheet1_Isothermal crystallization kinetics in bulk of olefin-based multiblock copolymers.pdf by Gaia Urciuoli (11725469)

“…The crystallization half time of the samples increases with increase of M_n and, for each sample, its logarithm increases linearly with a decrease of the undercooling by a factor of -0.155/°C, for the samples 1–4 and −0.031/°C, for the sample 5. …”

Ligand activation of ELIC. by Iwan Zimmermann (117942)

“…Macroscopic currents from a membrane patch in the outside-out configuration were recorded at −60 mV in response to a fast exchange into solutions containing 5 mM cysteamine. …”