Table2_Modelling the bottom-up effects of climate change on primary production in the Gulf of St. Lawrence and eastern Scotian Shelf.docx by Zhi-Ping Mei (19427332)

“…Results reveal a projected 13.4% decrease in annual primary production across the GSL system over the next 70 years. …”

Image_7_Modelling the bottom-up effects of climate change on primary production in the Gulf of St. Lawrence and eastern Scotian Shelf.png by Zhi-Ping Mei (19427332)

“…Results reveal a projected 13.4% decrease in annual primary production across the GSL system over the next 70 years. …”

Oxygen consumption (QO₂). by Mario Bianco (6894257)

“…The slopes of the lines gives a better comparison between the rates of [O₂] decrease during state 3 (dashed) and state 4 of respiration (dotted) in Sham (<b>D</b>), CL (<b>E</b>) and UUO (<b>F</b>) groups.…”

Image7_Modelling the bottom-up effects of climate change on primary production in the Gulf of St. Lawrence and eastern Scotian Shelf.png by Zhi-Ping Mei (19427332)

“…Results reveal a projected 13.4% decrease in annual primary production across the GSL system over the next 70 years. …”

Fig-7. The development of the glomerulocystic phenotype is progressively associated with loss of primary cilium. by Anna Iervolino (6712642)

“…Bars = 5 μm (A); 10 μm (B-D).</div>…”

DataSheet_1_Characterization of 3D heterocellular spheroids of pancreatic ductal adenocarcinoma for the study of cell interactions in the tumor immune microenvironment.docx by Giulio Giustarini (16544991)

“…Further, 4-culture tumor spheroids decreased the concentrations of T-cell chemoattracting cytokines, i.e., CCL4, CCL5, and CXCL9, when compared with the non-cancerous spheroids, revealing a critical immunosuppressive feature of the different types of cells forming the tumor spheroids. …”

DataSheet_1_Histidine-rich glycoprotein in metabolic dysfunction-associated steatohepatitis-related disease progression and liver carcinogenesis.pdf by Beatrice Foglia (3804862)

“…Background<p>Metabolic dysfunction-associated steatotic liver disease (MASLD), previously non-alcoholic fatty liver disease (NAFLD), is a leading cause of chronic liver disease worldwide. …”

Distributions of genetic diversity exhibit similar statistical forms across phylogenetically distant species in the human gut. by William R. Shoemaker (16632093)

“…In <b>c</b>, statistical fits of a gamma (the distribution predicted by the SLM) and a lognormal (a point of comparison) are illustrated as black lines. …”

Image1_Evaluation of the mechanism of action of paracetamol, drotaverine, and peppermint oil and their effects in combination with hyoscine butylbromide on colonic motility: human... by Sara Traserra (11013556)

“…Drotaverine, paracetamol, and peppermint oil were tested alone and in combination with hyoscine butylbromide on (1) spontaneous contractility induced by isometric stretch (in the presence of 1 µM tetrodotoxin) and (2) contractility induced by 10^–5 M carbachol and after (3) electrical field stimulation-induced selective stimulation of excitatory (in the presence of 1 mM Nω-nitro-L-arginine and 10 µM MRS2179) and (4) inhibitory (under non-adrenergic, non-cholinergic conditions) pathways. (5) Drotaverine alone was also tested on cAMP-dependent pathway activated by forskolin.…”

Table2_Evaluation of the mechanism of action of paracetamol, drotaverine, and peppermint oil and their effects in combination with hyoscine butylbromide on colonic motility: human... by Sara Traserra (11013556)

“…Drotaverine, paracetamol, and peppermint oil were tested alone and in combination with hyoscine butylbromide on (1) spontaneous contractility induced by isometric stretch (in the presence of 1 µM tetrodotoxin) and (2) contractility induced by 10^–5 M carbachol and after (3) electrical field stimulation-induced selective stimulation of excitatory (in the presence of 1 mM Nω-nitro-L-arginine and 10 µM MRS2179) and (4) inhibitory (under non-adrenergic, non-cholinergic conditions) pathways. (5) Drotaverine alone was also tested on cAMP-dependent pathway activated by forskolin.…”

Table1_Evaluation of the mechanism of action of paracetamol, drotaverine, and peppermint oil and their effects in combination with hyoscine butylbromide on colonic motility: human... by Sara Traserra (11013556)

“…Drotaverine, paracetamol, and peppermint oil were tested alone and in combination with hyoscine butylbromide on (1) spontaneous contractility induced by isometric stretch (in the presence of 1 µM tetrodotoxin) and (2) contractility induced by 10^–5 M carbachol and after (3) electrical field stimulation-induced selective stimulation of excitatory (in the presence of 1 mM Nω-nitro-L-arginine and 10 µM MRS2179) and (4) inhibitory (under non-adrenergic, non-cholinergic conditions) pathways. (5) Drotaverine alone was also tested on cAMP-dependent pathway activated by forskolin.…”

TRPV4 mediated calcium influx after stretch. by N. Pairet (5109128)

“…(B) Summary of the mean % Ca²⁺ response from the 60 sec after stretch, a 2.5 fold increase in the [Ca2+]_i was observed that was significantly decreased by 26% with the TRPV4 antagonist (1 <b>μ</b>M) GSK2193874 (184.5 ± 5.07 vs 248.6 ± 10.17). …”

Cytoprotective gene regulation is essential to lifespan extension by diverse mechanisms. by David E. Shore (123998)

“…Lifespan was measured in three replicates comprising an average of 103 worms per condition. Data is presented as mean lifespan (columns 1–4), change mean lifespan in comparison to an empty vector RNAi control (column 5), or as the change in the extension of lifespan induced by each long-lived mutant (columns 6–8; for clarity, only decreases >15% are shown). …”

Chemical inhibition of Erb signalling rescues the <i>pde</i> phenotype. by Karen Camargo-Sosa (3809491)

“…<p>(<b>A-H</b>) Treatment of <i>pde</i> embryos with increasing concentrations of Erb inhibitor PD158780 (iErb; 0.5–2.0 μM) or DMSO carrier control from 12–48 hpf (A-D), 19–30 hpf (E-H) and 24–30 hpf (I-L) hpf. …”

PIK3CA promoter activity in SKOV3 (p53 deficient) tumor xenograft model after cisplatin treatment. by Snehal M. Gaikwad (279479)

“…Mouse from control and treated group exhibited specific [Fig. 4a3 (pre-treatment)] signals which did not decrease even after two treatments of cisplatin [Fig. 4a3 (post-treatment)].…”

Methylation Analysis of CpG Orphans by Nicholas C Wong (14627)

“…CpG dinucleotides that are putative MeCP2-binding sites are indicated by solid diamonds. Upon treatment with 5-aza-dC, a number of CpG orphans (Op-4, Op-9, Op-11, Op-12, Op-17, and Op-18) demonstrated a significant decrease in DNA methylation.…”

PTZ increased exploratory behavior in entrained animals during memory tests. by Norman F. Ruby (263642)

“…<p>Arm entries and exploration times for animals from <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0072433#pone-0072433-g005" target="_blank">figure 5</a>. …”

Schematic of the reaction observed in real time with the 8-spot smFRET setup. by Antonino Ingargiola (2993055)

“…Complementary DNA strands are labeled at DNA promoter bases with donor (D, green, position -5) and acceptor (A, red, position -8) dyes. After formation of a transcription initiation bubble, the dyes are separated, resulting in medium FRET. …”

Tumour growth results. by Ahmed El Kaffas (552465)

“…Combined USMB+XRT+Dll4 mAb was observed to induce the greatest response, with a decrease in tumour size at 5 days after treatment, followed by growth inhibition lasting for nearly 15 days. …”

DNA fluorescent <i>in situ</i> hybridization confirms the presence of VZV genomes in nuclei of hESC-derived neurons quiescently infected with VZV. by Amos Markus (749748)

“…(C) FISH for VZV genomes in quiescently infected neurons receiving the PI3K inhibitor LY as a reactivation stimulus. After LY treatment there was a slight decrease in the percentage of FISH+ nuclei in the preparations, but 25% of labeled nuclei contained 2 or more puncta, suggesting additional sites of VZV genomes had appeared. …”