New Approaches for Biomarker Discovery: The Search for Liver Fibrosis Markers in Hepatitis C Patients by Bevin Gangadharan (156036)

“…To overcome this problem, we used two-dimensional gel electrophoresis (2-DE) over a narrow pH 3−5.6 range since this lies outside the range of highly abundant albumin, transferrin and immunoglobulins. …”

Effect of Testosterone on Proliferation Markers and Apoptosis in Breasts of Ovariectomized Rats by Jussara Celi Conceição Oliveira (8401119)

“…<div><p>Abstract Objective To investigate the action of testosterone (T), isolated or associated with estradiol benzoate (EB), on the proliferation markers and apoptosis of breasts of ovariectomized rats. Methods A total of 48 castrated female Wistar rats were divided into 6 groups, and each of them were submitted to one of the following treatments for 5 weeks: 1) control; 2) EB 50 mcg/day + T 50 mcg/day; 3) T 50mcg/day; 4) EB 50 mcg +T 300 mcg/day; 5) T 300 mcg/day; and 6) EB 50 mcg/day. …”

Supplementary Material for: The impact of mesalazine pill burden on compliance in inflammatory bowel disease patients by figshare admin karger (2628495)

“…Conclusion: The results showed a consistent higher adherence with the decrease of pill burden. …”

Structural understanding versus numerical analysis of Turing patterns, by Selim Haj Ali (21222613)

“…(d), (e) and (f) represent the dispersion relation for a Gierer-Meinhardt model [<a href="https://journals.plos.org/complexsystems//article/info:doi/10.1371/journal.pcsy.0000044#pcsy.0000044.ref026" target="_blank">26</a>] with reaction parameters <i>a</i>₅ = 0.27 and <i>b</i>₅ = 1.57 and diffusion parameters and , zoomed into the three eigenmodes <i>S</i>, <i>M</i> and <i>U</i> around the Turing instability regime. …”

LncRNAs are expressed in leukocytes and exhibit differential expression in PD and following DBS. by Lilach Soreq (89966)

“…<p>Over 5,800 lncRNAs were detected as expressed in RNA from PD patient's leukocyte pre- and post-DBS (both on and off electrical stimulation) and in control leukocyte RNA samples through alignment of the RNA-Seq read counts to GENCODE database (A). …”

Public health and budgetary impact of 20-valent pneumococcal conjugate vaccine for adults in England by Tendai Mugwagwa (2580760)

“…The budgetary impact would be greatest in year 1 (£26.3 M), and would decrease over time (to £1.6 M by year 5). The average budget increase (£11.7 M/year) represents <0.01% of the Department of Health and Social Care total budget and <3% of the vaccine budget.…”

Significantly altered metabolites in CSF of dKO rats (compared to WT) display unique metabolite-class signatures. by Samit Ganguly (1792294)

“…Similarly, metabolites with 1.5-fold increase or decrease are identified with vertical red and green lines, respectively. …”

Carbosiloxane Bottlebrush Networks for Enhanced Performance and Recyclability by Taejun Eom (17300332)

“…The recovered monomer was successfully repolymerized through anionic ring-opening polymerization with no decrease in structural fidelity or activity. In summary, this combination of unique (macro)monomer design and bottlebrush architecture creates new opportunities in sustainable practices by offering a robust, recyclable alternative to commercial silicone-based materials.…”

Changes in p53 and AMPKα phosphorylation as well as apoptosis rate in neonatal rat cardiomyocytes after DOX, Ber or/and compound C treatment. by Xiuxiu Lv (303049)

“…<p>Cardiomyocytes were exposed to DOX (1.0 µM) or/and Ber (1.0 µM) for 2 h, p53 and p-p53 protein levels (A, n = 4) as well as AMPKα and p-AMPKα (Thr172) protein levels (B, n = 5) were detected by Western blot assay. …”

Carbosiloxane Bottlebrush Networks for Enhanced Performance and Recyclability by Taejun Eom (17300332)

“…The recovered monomer was successfully repolymerized through anionic ring-opening polymerization with no decrease in structural fidelity or activity. In summary, this combination of unique (macro)monomer design and bottlebrush architecture creates new opportunities in sustainable practices by offering a robust, recyclable alternative to commercial silicone-based materials.…”

Effects of <i>OCT4</i> knockout on bovine early embryonic development. by Lei Luo (284798)

“…G and H: <i>OCT4</i> KO results in the decrease of blastocyst rate at D8.5 (Three replicates of 20–25 embryos per group). …”

Schematic representation of CD47-mediated PCD in CLL cells. by Ana-Carolina Martinez-Torres (697374)

Sound pressure and frequency dependencies of CAP and CM amplitude changes after cortical deactivation with lidocaine. by Alex León (167617)

Hypoxia increased basal [Ca²⁺]_i of PVSMCs <i>in vivo</i> and <i>in vitro</i>. by Lei Xu (78676)

“…<p><b>A</b>: Time course effects of hypoxia on basal [Ca²⁺]_i change before and after restoration of extracellular Ca²⁺ to 2.5 mM in distal PVSMCs perfused with Ca²⁺-free Kreb solution containing 10 µM CPA, 1 mM EGTA and 5 µM nifedipine. …”

Table_3_Does Prefrontal Glutamate Index Cognitive Changes in Parkinson’s Disease?.docx by Isabelle Buard (6375827)

“…Introduction<p>Cognitive impairment is a highly prevalent non-motor feature of Parkinson’s disease (PD). …”

Table_1_Toll-Like Receptor 4 Protects Against Clostridium perfringens Infection in Mice.xlsx by Masaya Takehara (847765)

“…Here, TLR4-defective C3H/HeJ mice infected with C. perfringens showed a remarkable decrease in survival rate, an increase in viable bacterial counts, and accelerated destruction of myofibrils at the infection site compared with wild-type C3H/HeN mice. …”

Spry1 is essential to maintain hAoSMC marker gene expression. by Xuehui Yang (225729)

“…C) Quantification of RT-qPCR from three independent experiments shows efficacy of knockdown (kd) of Spry1 and Spry4 mRNA by their respective shRNAs compared to a non-targeting sequence (NT). D) Quantification of RT-qPCR from three independent experiments shows that knockdown of Spry1 decreases, whereas knockdown of Spry4 increase VSMC differentiation gene expression at the mRNA level. …”

Travel time comparison between scenarios 1 and 3. by Elham Mortazavi Moghaddam (16015219)

“…In the present study, the non-dominated storing genetic algorithm (NSGA-II) solves the upper-level and a method of successive average (MSA) unravels the lower level of the model. …”

Quantitative Analysis of Protein Phosphorylations and Interactions by Multi-Colour IP-FCM as an Input for Kinetic Modelling of Signalling Networks by Sumit Deswal (211660)

“…A mechanistic mathematical model of the underlying processes demonstrated that an initial massive recruitment of non-phosphorylated ZAP70 was responsible for this behaviour. …”

The effect of (+)-pentazocine and H₂O₂ on ONHAs viability. by Jing Zhao (21160)

“…At the highest concentration of PTZ (50μM), there was a trend toward decrease in viability that was not significant. …”