Multiple Autoimmune-Associated Variants Confer Decreased IL-2R Signaling in CD4⁺CD25^hi T Cells of Type 1 Diabetic and Multiple Sclerosis Patients by Karen Cerosaletti (501670)

“…To examine this question we used phosphorylation of STAT5 (pSTAT5) as a downstream measure of IL-2R signaling, and found a decreased response to IL-2 in CD4⁺CD25^hi T cells of T1D and MS, but not SLE patients. …”

Overlayed expression profiles of cyclins A2 and B1. by James W. Jacobberger (184625)

“…Inset in D: zoomed view of initial decrease in both cyclins as cells enter mitosis. In A, B, and C, means (of median specific fluorescence) are shown. …”

Principal Component Analysis (PCA) and Metascape pathway analysis of differentially expressed genes in pediatric cholestatic liver disease (pCLD) samples (n = 10) compared to pedia... by Alyssa Kriegermeier (4707226)

Related to Fig 2. by Luciana I. Gómez Acuña (18605719)

Long-term apoptosis-related protein expression in the diabetic mouse ovary by Nicolas A. Fraunhoffer (5728364)

“…The main objective of the present study was to analyze the apoptosis pathways activated during follicular loss at multiple time points in a diabetic mouse model. Twenty BALB/c mice were used in this study, and diabetes mellitus was induced by streptozotocin injection. …”

<i>SpdA-ins</i> cells adhere more efficiently than WT cells to their substrate. by Marco Dias (290981)

“…Data from three independent experiments is represented in this graph. A decrease in cell detachment can be the result of an increase in the adhesion force (F) or of a decrease in h (i.e. of a more efficient cell spreading).…”

<i>miR-146a</i> LNA treatment inhibits OSCC oncogenicity. by Pei-Shi Hung (489732)

“…Lt, growth curve of xenografts. The folds are determined by normalization of tumor volume at different time points to the tumor volume at the time point receiving the injection of <i>miR-146a</i> LNA. …”

Structural and geometric features of connectivity modes. by Justine Y. Hansen (17041502)

Depression and Risk of Mortality in People with Diabetes Mellitus: A Systematic Review and Meta-Analysis by Fleur E. P. van Dooren (385472)

“…</p> <p>Conclusions</p><p>Depression is associated with an almost 1.5-fold increased risk of mortality in people with diabetes. …”

Significantly associated microbial species between the pre- and post-eradication states (at a significance level <i>p</i><0.05). by Dita Gudra (4439767)

Structure of THC and its tautomeric structure. by Zhi Xuan Low (19270163)

“…Through the presence of an inclusion complex, a higher aqueous dispersion (65-fold) resulting in a higher drug content and an elevated release profile was achieved. …”

UPR gene and protein expression of autoimmune hepatitis (AIH) livers compared to pediatric normal controls (pNormal) and pediatric cholestatic liver disease (pCLD) samples. by Alyssa Kriegermeier (4707226)

“…<p>A) Using qPCR, we determine that: compared to AIH livers (n = 5), pCLD livers (n = 10) had decreased expression of IRE1α, XBP1s, and EDEM1 by 78%, 77%, and 67% while ERdj4 gene expression was similar. …”

CypB KO mice exhibit differential gene expression compared to WT mice undergoing a NAFLD/NASH model. by Winston T. Stauffer (18086483)

Na_v1.6-BAD-GFP but not Na_v1.6-dABM-BAD-GFP co-localizes with axonal markers. by Elizabeth J. Akin (724295)

“…<b>A)</b> Na_v1.6 is enriched within the ankG positive AIS. …”

A rebalance of PtdIns(3,5)<i>P</i>₂ rescues <i>Mtmr2</i>-null myelin outfoldings <i>in vitro</i>. by Ilaria Vaccari (200528)

“…(D) Decrease of PIKfyve expression on lysates from myelin-forming Schwann cells/DRG explants transduced with PIKfyve shRNA lentiviral vector (LV), as compared to a scramble sequence. …”

Table_5_A Partially Phase-Separated Genome Sequence Assembly of the Vitis Rootstock ‘Börner’ (Vitis riparia × Vitis cinerea) and Its Exploitation for Marker Development and Targete... by Daniela Holtgräwe (642655)

“…<p>Grapevine breeding has become highly relevant due to upcoming challenges like climate change, a decrease in the number of available fungicides, increasing public concern about plant protection, and the demand for a sustainable production. …”

Based on flow cytometry analysis with the propidium iodide the irradiated (9h after IR) hiPSC-DCHs and mature chondrocytes pointed at accumulation and cell cycle arrest in G2 phase... by Ewelina Stelcer (5334791)

“…<p>In turn, hiPSCs exposed to IR demonstrated high level of cells found in S phase (A). All investigated cells (hiPSCs, hiPSC-DCHs and chondrocytes) showed little differences in ROS level measured–using CellROX Green Reagent and tert-butyl hydroperoxide as a positive control- immediately after IR. …”

QS signaling over <i>V. cholerae</i> biofilm development. by Grace E. Johnson (21376787)

“…<p><b>(A)</b> Average per-cell-volume <i>qrr</i>4 (<i>mNG</i>) and <i>hapR</i> fluorescence signal across <i>n </i>= 10 replicate WT <i>V. cholerae</i> biofilms as a function of the average biofilm biovolume. …”

lncRNA-GAS5 affects the cell cycle and apoptosis of HSVSMCs. by Li Li (14993)

“…The result shows that the HSVSMCs in early apoptosis decreased with overexpression of lncRNA-GAS5. N = 3; *, P<0.05.…”

The representative pattern of microdialysis values in the ischemic core and in the penumbra of animal #5. by Fuat Arikan (598158)

“…PtiO₂ data in animal #2 was consistent with the typical PtiO₂ profile observed in all but 1 animal (#5). In the ischemic core, a rapid decrease in [Glu]_brain was observed after occlusion, followed by a significant drop in [Pyr]_brain and a significant increase in [Lac]_brain and in the lactate/pyruvate ratio (LPR). …”