Effect of atorvastatin on HMGB1 and IL-8 levels in HUVEC supernatants. by Alexandre W. S. de Souza (556095)

“…HMGB1 intensity in supernatants increases 8 hours after stimulation and a peak is observed at 24 hours with a decrease at 48 hours. 2B and C – HMGB1 and IL-8 levels are significantly higher at 24 hours in supernatants from HUVEC treated with LPS in comparison to unstimulated HUVEC while pre-incubation with 5 µM atorvastatin followed by LPS stimulation lowered HMGB1 and IL-8 levels significantly at 24 hours in HUVEC's supernatants. …”

Crude glycerol in diets for Nile tilapia in the fattening stage by Lilian Dena dos Santos (7368332)

“…Two hundred Nile tilapia (190±4.5 g) were distributed in 20 tanks, in a completely randomized design. …”

Summary of results & proposed feedback model. by Rainer Machné (160042)

“…<p>7A: temporal flow of expression and functional relationships of cluster transcripts in the 0.7 h system (left to right) and the 5 h system (top to bottom). 7B: summary of observed properties (significant enrichment or biases) of the main gene clusters. 7C: Potential regulatory interactions of broad cellular functionality <i>via</i> the energetic status of the cell, reflected, <i>e</i>.g., in ATP:ADP ratios. …”

Physiological maturation in seeds of Lophantera lactescens Ducke by Patrícia Cândido da Cruz Silva (6299252)

“…A light-brown coloration with wrinkling of the fruit pericarp is a good visual indicator for determining the point of physiological maturity of the seeds in this species. …”

Blood pressure documentation in the emergency department by Ana Carolina Queiroz Godoy Daniel (4650613)

“…Of these measures, 46.5% were abnormal. The mean time from admission to documentation of the first blood pressure measurement was 2.5 minutes, with 42 minutes between subsequent measures. …”

Predicted miRNAs are expressed in C2C12 cells and skeletal muscle and can target the utrophin 3′-UTR. by Utpal Basu (190371)

“…All six miRNAs are expressed in C2C12 cells. miR-150 was not detected (n.d.) in TA, while miR-296-5p was n.d. in TA or soleus. Bars represent mean ± SD. …”

AZD1480 leads to TPC-1 xenograft tumor remission. by Joana P. Couto (130525)

“…Following tumor engraftment (∼0.5 cm³), mice were distributed into four groups (n = 5/group) with similar mean tumor volumes. …”

The Laminin Response in Inflammatory Bowel Disease: Protection or Malignancy? by Caroline Spenlé (161321)

“…Here we showed first that in human IBD colonic samples and in murine colitis the LMα1 and LMα5 chains are specifically and ectopically overexpressed with a concomitant nuclear p53 accumulation. …”

PLYOMETRIC TRAINING IMPROVES SWIMMING PERFORMANCE IN RECREATIONALLY-TRAINED SWIMMERS by Rodrigo Cañas-Jamett (10403402)

“…In addition, sit-and-reach flexibility and squat jump tests were conducted, as well as a 200m swimming trial. Results: Two-way ANOVA with post-hoc analysis revealed an increase in sit-and-reach flexibility (PRE: 4.5±5.3 cm; POST: 10.9±5.9 cm, p<0.01) and squat jump height (PRE: 24.9±3.7 cm; POST: 28.3±4.2 cm, p<0.01) and a decrease in 200m-swimming time (PRE: 220±26.5 sec; POST: 204±24.4 sec, p<0.01) for the PTG only. …”

Effects of acute leptin suppression on activity in Tet-off hyperleptinemic transgenic <i>obob</i> mice. by Ana C. Ribeiro (210764)

“…(<i>F</i>) Leptin suppression also significantly decreased RWA in Tg <i>obob</i> (n = 5) although at a slower rate becoming significant at day 20 (p<0.05). …”

GENomE wide analysis of sotalol-induced IKr inhibition during ventricular REPOLarization, “GENEREPOL study”: Lack of common variants with large effect sizes by Joe-Elie Salem (4351000)

“…QTc and TpTe increased by 5.5±3.5% and 15±19.6%, respectively, and TAmp decreased by 13.2±15.5%. …”

Supplementary Material for: Design and Baseline Characteristics of the Finerenone in Reducing Kidney Failure and Disease Progression in Diabetic Kidney Disease Trial by Bakris G.L. (4681903)

“…The study has at least 90% power to detect a 20% reduction in the risk of primary outcome (overall two-sided significance level α = 0.05), the composite of time to first occurrence of kidney failure, a sustained decrease of eGFR ≥40% from baseline over at least 4 weeks, or renal death. …”

QUALIS: The journal ranking system undermining the impact of Brazilian science by RODOLFO JAFFÉ (10364631)

Attacks on healthcare facilities as an indicator of violence against civilians in Syria: An exploratory analysis of open-source data by Sayaka Ri (3194364)

“…This model adjusted for population displacement (using number of registered refugees as a proxy). The May 2014 interaction term, used a transition point of early/late war based on political events during that time, illustrated that each healthcare facility attack after May 2014 corresponded to a statistically significant decrease of 228 civilian deaths. …”

Data_Sheet_1_Influence of Community-Led Total Sanitation and Water Coverages in the Control of Cholera in Madarounfa, Niger (2018).docx by Julien Graveleau (10717281)

“…Considering only the villages affected by cholera in the studied area, cholera cases decrease by a factor of 4.3 in those villages where there is partial access to at least quality water sources, while full access to improved water sources decreases the cholera cases by a factor of 6.3 when compared to villages without access to water (P < 0.001). …”

In vivo induction of hepatocellular carcinoma by diethylnitrosoamine and pharmacological intervention in Balb C mice using Bergenia ciliata extracts by K. K. Dar (6274934)

“…The intraperitoneal administration of B. ciliata as a protective agent, produced significant increase in albumin levels with significant decrease in the levels of tumor markers aspartate aminotransferase (AST), alanine aminotransferase (ALT), lactate dehydrogenase (LDH), alpha feto protein (AFP), gamma glutamyl transferase (Y-GT), 5 nucleotidase (5NT), glucose-6-phosphate dehydrogenase (G6PDH) and bilirubin. …”

In vivo induction of hepatocellular carcinoma by diethylnitrosoamine and pharmacological intervention in Balb C mice using Bergenia ciliata extracts by K. K. Dar (6274934)

“…The intraperitoneal administration of B. ciliata as a protective agent, produced significant increase in albumin levels with significant decrease in the levels of tumor markers aspartate aminotransferase (AST), alanine aminotransferase (ALT), lactate dehydrogenase (LDH), alpha feto protein (AFP), gamma glutamyl transferase (Y-GT), 5 nucleotidase (5NT), glucose-6-phosphate dehydrogenase (G6PDH) and bilirubin. …”

Trademark gene expression patterns of human psoriasis and expression of orthologous genes in mouse psoriasiform phenotypes. by William R. Swindell (175427)

“…The colors in (A) and (B) correspond to the observed fold-change difference between expression in psoriasiform mouse skin and normal skin obtained from control mice, with red indicating elevated expression in psoriasiform skin and green indicating decreased expression (see scale). …”

Table_1_Favorable Effects of Tacrolimus Monotherapy on Myasthenia Gravis Patients.DOCX by Zhirong Fan (9566711)

“…QMG scores significantly decreased at 6 and 12 months, with mean differences and 95% CIs of −4.67(−6.88, −2.45) and −5.77 (−7.55, −4.00), respectively. …”

Table_1_Clinically important change on the Unified Dyskinesia Rating Scale among patients with Parkinson's disease experiencing dyskinesia.DOCX by Rajesh Pahwa (6816655)

“…UDysRS reduction of ≥9 points corresponded to decreased ON time with troublesome dyskinesia of ≥0.5 h per patient diaries, and UDysRS reduction of ≥10 points corresponded to at least minimal improvement on the CGI-C.…”