Proteomics investigation of the changes in serum proteins after high- and low-flux hemodialysis by Shuai Han (545347)

“…Among the increased and decreased proteins, the isoelectric point (pI) values mainly ranged from 5 to 7, and the molecular weights (Mws) were mostly smaller than 30 kDa. …”

The proposed development and evaluation strategy for SSP methods and its feasibility tests. by Teng-Ruei Chen (9046518)

“…<p><b>(A)</b> The layout of datasets. We propose the homology between and within all developmental datasets, meaning the training and testing query sets and the PSSM reference dataset, should be as low as possible. …”

Table 1_Quantitative N-glycoproteomic analysis reveals glycosylation signatures of plasma immunoglobulin G in systemic sclerosis.xlsx by Lu Cheng (141959)

“…The correlation of specific intact N-glycopeptides with the clinical features of SSc patients was analyzed. The results revealed a notable increase in the levels of 6 intact N-glycopeptides (IgG2-N3H3F1, IgG2-N3H4F1, IgG2-N4H4F1, IgG2-N4H5F1, IgG2-N5H4F1, and IgG2-N5H5F1) and a decrease in the levels of another set of 6 intact N-glycopeptides (IgG1-N4H3F1, IgG2-N3H6F1A1, IgG2-N4H4F1A1, IgG2-N5H3F1, IgG3-N4H3F1, and IgG3-N4H4F1). …”

Table 2_Quantitative N-glycoproteomic analysis reveals glycosylation signatures of plasma immunoglobulin G in systemic sclerosis.xlsx by Lu Cheng (141959)

“…The correlation of specific intact N-glycopeptides with the clinical features of SSc patients was analyzed. The results revealed a notable increase in the levels of 6 intact N-glycopeptides (IgG2-N3H3F1, IgG2-N3H4F1, IgG2-N4H4F1, IgG2-N4H5F1, IgG2-N5H4F1, and IgG2-N5H5F1) and a decrease in the levels of another set of 6 intact N-glycopeptides (IgG1-N4H3F1, IgG2-N3H6F1A1, IgG2-N4H4F1A1, IgG2-N5H3F1, IgG3-N4H3F1, and IgG3-N4H4F1). …”

Table 4_Quantitative N-glycoproteomic analysis reveals glycosylation signatures of plasma immunoglobulin G in systemic sclerosis.xlsx by Lu Cheng (141959)

“…The correlation of specific intact N-glycopeptides with the clinical features of SSc patients was analyzed. The results revealed a notable increase in the levels of 6 intact N-glycopeptides (IgG2-N3H3F1, IgG2-N3H4F1, IgG2-N4H4F1, IgG2-N4H5F1, IgG2-N5H4F1, and IgG2-N5H5F1) and a decrease in the levels of another set of 6 intact N-glycopeptides (IgG1-N4H3F1, IgG2-N3H6F1A1, IgG2-N4H4F1A1, IgG2-N5H3F1, IgG3-N4H3F1, and IgG3-N4H4F1). …”

Data Sheet 1_Quantitative N-glycoproteomic analysis reveals glycosylation signatures of plasma immunoglobulin G in systemic sclerosis.doc by Lu Cheng (141959)

“…The correlation of specific intact N-glycopeptides with the clinical features of SSc patients was analyzed. The results revealed a notable increase in the levels of 6 intact N-glycopeptides (IgG2-N3H3F1, IgG2-N3H4F1, IgG2-N4H4F1, IgG2-N4H5F1, IgG2-N5H4F1, and IgG2-N5H5F1) and a decrease in the levels of another set of 6 intact N-glycopeptides (IgG1-N4H3F1, IgG2-N3H6F1A1, IgG2-N4H4F1A1, IgG2-N5H3F1, IgG3-N4H3F1, and IgG3-N4H4F1). …”

Biomarkers and overall survival in patients with advanced hepatocellular carcinoma treated with TGF-βRI inhibitor galunisertib by Gianluigi Giannelli (94866)

“…In AFP responders (21% of patients in Part A with decrease of >20% from baseline) versus non-responders, median OS was 21.5 months versus 6.8 months (p = 0.0015). …”

Table 3_Quantitative N-glycoproteomic analysis reveals glycosylation signatures of plasma immunoglobulin G in systemic sclerosis.xlsx by Lu Cheng (141959)

“…The correlation of specific intact N-glycopeptides with the clinical features of SSc patients was analyzed. The results revealed a notable increase in the levels of 6 intact N-glycopeptides (IgG2-N3H3F1, IgG2-N3H4F1, IgG2-N4H4F1, IgG2-N4H5F1, IgG2-N5H4F1, and IgG2-N5H5F1) and a decrease in the levels of another set of 6 intact N-glycopeptides (IgG1-N4H3F1, IgG2-N3H6F1A1, IgG2-N4H4F1A1, IgG2-N5H3F1, IgG3-N4H3F1, and IgG3-N4H4F1). …”

Fe- and Ln-DOTAm-F12 Are Effective Paramagnetic Fluorine Contrast Agents for MRI in Water and Blood by Kriti Srivastava (2231482)

“…This increased sensitivity is due to a substantialup to 100-folddecrease in the longitudinal relaxation time (<i>T</i>₁) of the fluorine nuclei. …”

Exploration of possible direct <i>miR-195</i> and <i>miR-497</i> targets by Ago2-IP experiment. by Mayuko Furuta (395068)

“…<b>B</b>, Outline for selecting final candidates as direct targets of <i>miR-195</i> (<b><i>upper</i></b>) and <i>miR-497</i> (<b><i>lower</i></b>) determined by a combination of Ago2-IP candidates and repressed genes by <i>miR-195</i> or <i>miR-497</i> (>2-fold decrease) in gene expression array experiments. …”

Glycolytic inhibitor 2-DG alters downstream AMPK and mTOR signaling, and neuronal gene expression, but does not affect Wnt signaling. by Roaya S. Alqurashi (11243136)

“…Representative western blots with quantified data showed 2-DG treatment at day 5 post-SE with pilocarpine inhibit mTOR signaling downstream activation by decreased pP70S6K^T389 and activating pAMPKα^T172. …”

Increasing Notch1 activity in MAFs suppresses tumor angiogenesis. by Hongwei Shao (493627)

“…<i>Top</i>: representative images; <i>Bottom</i>: relative blood vessel density calculated as % of red pixel in total area examined by confocal microscopy. Data are mean ± SD, n = 5 tumors/group. <b>B.</b> Significantly decreased blood vessel density is observed in 1205Lu co-grafted with N1^IC-GFP/MAF. …”

Signaling pathway analysis following MCSF and RANKL treatment. by Muzaffer Cicek (227597)

“…<p><b>A</b>. Osteoclast precursors at day 3 and mature osteoclasts at day 4 were serum-starved and treated with MCSF, RANKL or MCSF+RANKL as indicated for five minutes. …”

Image_1_Cortico-Striatal Oscillations Are Correlated to Motor Activity Levels in Both Physiological and Parkinsonian Conditions.pdf by Cristóbal Moënne-Loccoz (9237122)

“…In motor cortices and striata, we observed a robust correlation between the motion index and the oscillatory power in two main broad frequency ranges: a low-frequency range [5.0–26.5 Hz] was negatively correlated to motor activity, whereas a high-frequency range [35.0–79.9 Hz] was positively correlated. …”

Chlorogenic Acid Prevents Osteoporosis by Shp2/PI3K/Akt Pathway in Ovariectomized Rats by Rong Ping Zhou (3607778)

“…Sixty female Sprague-Dawley rats were divided randomly among a sham-operated group and five ovariectomy (OVX) plus treatment subgroups: saline vehicle, 17α-ethinylestradiol (E2), or CGA at 9, 27, or 45 mg/kg/d. …”

Table_1_Characterization of the Teleneurology Patients at the Hospital Las Higueras de Talcahuano—Chile.XLSX by Freddy Constanzo (6882176)

“…The patients were referred to a neurologist in the teleneurology program from different primary healthcare centers (93.5%) and tertiary healthcare centers (6.5%). …”

Data_Sheet_1_Cold Acclimation and Deacclimation of Two Garden Rose Cultivars Under Controlled Daylength and Temperature.docx by Lin Ouyang (8466462)

“…Increasing the temperature after a cold period resulted in fast deacclimation as found by the downregulation of RhDHN5 and RhBAM3, the decrease of raffinose and stachyose. …”

Endoglin Requirement for BMP9 Signaling in Endothelial Cells Reveals New Mechanism of Action for Selective Anti-Endoglin Antibodies by Olivier Nolan-Stevaux (106964)

“…<em>ENG</em> and <em>ACVRL1</em> are both required for angiogenesis and mutations in either gene are associated with Hereditary Hemorrhagic Telangectasia, a rare genetic vascular disorder. ENG and ALK1 function in the same genetic pathway but the relative contribution of TGFβ and BMP9 to SMAD1/5/8 activation and the requirement of ENG as a co-mediator of SMAD phosphorylation in endothelial cells remain debated. …”

Greater accumulation of exopolymeric matrix on Asc10⁺<i>E. faecalis</i> biofilms, in comparison to Asc10⁻ biofilms. by Olivia N. Chuang-Smith (160012)

“…<p>Scanning electron micrographs of <i>E. faecalis</i> Asc10⁺ OG1SSp (pCF10) incubated 0.5 h (<b>A</b>) and 2 h (<b>B</b>) showing typical comparatively smooth appearance of the bacterial surface at early incubation times (<b>A</b>) compared to the fibrillar strands that became more evident over time (<b>B</b>). …”

Supplementary Material for: Influence of Antipsychotic Agents on Heart Rate Variability in Male WKY Rats: Implications for Cardiovascular Safety by Wang Y.-C. (4132195)

“…<b><i>Conclusion:</i></b> Taking this evidence as a whole, we conclude that haloperidol has a better level of cardiovascular safety than either risperidone or clozapine. …”