Image_2_SHANK2 Mutations Result in Dysregulation of the ERK1/2 Pathway in Human Induced Pluripotent Stem Cells-Derived Neurons and Shank2(−/−) Mice.JPEG by Anne-Kathrin Lutz (11758967)

“…Neuronal proliferation was increased, and apoptosis was decreased in young and mature neurons. Additionally, mature patient hiPSC-derived neurons showed dysregulated excitatory signaling and a decrease of a broad range of signaling molecules of the ERK-MAP kinase pathway. …”

Image_4_SHANK2 Mutations Result in Dysregulation of the ERK1/2 Pathway in Human Induced Pluripotent Stem Cells-Derived Neurons and Shank2(−/−) Mice.JPEG by Anne-Kathrin Lutz (11758967)

“…Neuronal proliferation was increased, and apoptosis was decreased in young and mature neurons. Additionally, mature patient hiPSC-derived neurons showed dysregulated excitatory signaling and a decrease of a broad range of signaling molecules of the ERK-MAP kinase pathway. …”

Table_2_Glucocorticoid Effects on Tissue Residing Immune Cells in Giant Cell Arteritis: Importance of GM-CSF.DOCX by Annette D. Wagner (6496358)

“…A decrease of CCL19 and CCL21 expression was observed after starting glucocorticoid therapy. …”

Luminex results of cytokines regulated by IL-1Ra. by Connie S. Chamberlain (440242)

“…Blockade of the IL-1 activation resulted in an accumulation of IL-1α (a) and IL-1β (b). By day 11, inhibition of the IL-1R resulted in a down-regulation of IL-1α (a) and tended to decrease IL-1β (b; p = .056). …”

Theophylline attenuates bleomycin-induced oxidative stress in rats: The role of IL-6, NF-κB, and antioxidant enzymes by Suat Ekin (6165095)

“…Assigned into 4 groups were 32 Wistar albino rats, comprising the control group (administered 0.9% isotonic saline), BLM group (treated with BLM at a dose of 2.5 mg/kg), BLM+Theo group (treated with Theo at a dose of 75 mg/kg + BLM at a dose of 2.5 mg/kg), and Theo group (treated with Theo at a dose of 75 mg/kg). …”

Presentation_1_Glucocorticoid Effects on Tissue Residing Immune Cells in Giant Cell Arteritis: Importance of GM-CSF.PPT by Annette D. Wagner (6496358)

“…A decrease of CCL19 and CCL21 expression was observed after starting glucocorticoid therapy. …”

Image_3_SHANK2 Mutations Result in Dysregulation of the ERK1/2 Pathway in Human Induced Pluripotent Stem Cells-Derived Neurons and Shank2(−/−) Mice.JPEG by Anne-Kathrin Lutz (11758967)

“…Neuronal proliferation was increased, and apoptosis was decreased in young and mature neurons. Additionally, mature patient hiPSC-derived neurons showed dysregulated excitatory signaling and a decrease of a broad range of signaling molecules of the ERK-MAP kinase pathway. …”

Ni-Assisted Transformation of Graphene Flakes to Fullerenes by Irina V. Lebedeva (347621)

“…The Ni clusters are shown to reduce the activation energy for the graphene–fullerene transformation from 4.0 eV to 1.5–1.9 eV, providing the decrease of the minimal temperature at which such a transformation can be observed experimentally from about 1400 K for free graphene flakes to about 700–800 K. …”

Orientation tuning curves of neuron pairs responding to drifting gratings were recorded in area 17 by Narcis Ghisovan (94543)

“…Color code – blue: control, red: adaptation, green: 60 minutes later (error bars denote SEM). (A) Example of an adaptation-induced shift of 18.5° to the right for the cell GM1-x1 and a small shift of 4.5° in the same direction for the other cell GM1-y1. …”

Ni-Assisted Transformation of Graphene Flakes to Fullerenes by Irina V. Lebedeva (347621)

“…The Ni clusters are shown to reduce the activation energy for the graphene–fullerene transformation from 4.0 eV to 1.5–1.9 eV, providing the decrease of the minimal temperature at which such a transformation can be observed experimentally from about 1400 K for free graphene flakes to about 700–800 K. …”

Image_1_SHANK2 Mutations Result in Dysregulation of the ERK1/2 Pathway in Human Induced Pluripotent Stem Cells-Derived Neurons and Shank2(−/−) Mice.JPEG by Anne-Kathrin Lutz (11758967)

“…Neuronal proliferation was increased, and apoptosis was decreased in young and mature neurons. Additionally, mature patient hiPSC-derived neurons showed dysregulated excitatory signaling and a decrease of a broad range of signaling molecules of the ERK-MAP kinase pathway. …”

Balloon-Expandable Transcatheter Mitral Valve Replacement Through Minimally Invasive Approach in Big MAC by Daiana Nerea Romero (9647253)

“…Lastly, the attachment of the pericardial patch within the atrium was performed with a circumferential running suture with a 5.0 polypropylene suture. …”

TIME SERIES TRENDS OF STREAMFLOW AND RAINFALL IN THE SANTO ANTÔNIO RIVER BASIN, BRAZIL by Fernanda L. V. Ferreira (10383961)

SirR regulates gene expression of the stress response in <i>S</i>. <i>pneumoniae</i>. by Nicolás M. Reinoso-Vizcaíno (9239763)

“…<p>(A) RNA-seq heatmap shows gene expression of the comparison between the Δ<i>sirR</i> and <i>wt</i> strains incubated in ABM with relative gene expression in log₂ fold change demonstrating increased expression in green and decreased expression in red. …”

Image1_Impact of in Utero Rat Exposure to 17Alpha-Ethinylestradiol or Genistein on Testicular Development and Germ Cell Gene Expression.JPEG by Laetitia L. Lecante (12716315)

“…Analysis of differentially expressed genes (DEGs) (p < 0.05; fold change 1.5) identified expression changes of 149 and 128 transcripts by EE2 and GE respectively at GD20, and 287 and 207 transcripts at PND5, revealing an increased effect after the end of treatment. …”

Table1_Impact of in Utero Rat Exposure to 17Alpha-Ethinylestradiol or Genistein on Testicular Development and Germ Cell Gene Expression.DOC by Laetitia L. Lecante (12716315)

“…Analysis of differentially expressed genes (DEGs) (p < 0.05; fold change 1.5) identified expression changes of 149 and 128 transcripts by EE2 and GE respectively at GD20, and 287 and 207 transcripts at PND5, revealing an increased effect after the end of treatment. …”

Data Sheet 1_The effects and mechanism of urease inhibitor and its combination with nitrification inhibitor on nitrous oxide emission across four soil types.docx by Churong Liu (11174070)

“…N fertilization significantly increased N₂O emissions by 5.1~99.9-fold and elevated CO₂ emissions by 13.6~65.4% across all soil types. …”

Image_1_Changes in social isolation and loneliness prevalence during the COVID-19 pandemic in Japan: The JACSIS 2020–2021 study.TIFF by Hiroshi Murayama (765347)

“…The weighted mean scores of the UCLA Loneliness Scale were 5.03 (4.86, 5.20) in 2020 and 5.86 (5.81, 5.91) in 2021, representing a change of 0.83 points (0.66, 1.00). …”

Quantitative comparison of differentially expressed transcripts and the biological responses that are significantly enriched in mast cells by AgNPs. by Monica Johnson (4993490)

“…Significance was set at <i>p</i>≤0.05 with a fold enrichment cutoff of ≥5. RTK, receptor tyrosine kinase; MAPK, mitogen-activated protein kinase.…”

Molecular Profiling Associated with Calcium/Calmodulin-Dependent Protein Kinase Kinase 2 (CAMKK2)-Mediated Carcinogenesis in Gastric Cancer by Mohd. Altaf Najar (10586881)

“…In addition, tandem mass tag (TMT)-based quantitative proteomic analysis resulted in the identification of 7609 proteins, of which 219 proteins were found to be overexpressed and 718 downregulated (1.5-fold). Our data identified several key downregulated proteins involved in cell division and cell proliferation, which included DNA replication licensing factors, replication factor C, origin recognition complex, replication protein A and GINS, and mesenchymal markers, upon CAMKK2 inhibition. …”