TGF-β1 signaling regulates steroidogenic gene expression, affecting testicular testosterone levels in mice. by Eunsook Park (299902)

“…<p>(<b>A</b>) Decreased Tgfbr2^fl°^x allele in purified primary Leydig cells isolated from mice harboring the Cyp17iCre transgene. …”

PfeIF2α-P levels after gradual PPQ treatments. by Michal Kucharski (4383256)

“…<p>Western blot analysis of PfeIF2α-P levels under 500 nM DHA stress in ring parasites simultaneously co-treated with gradually decreasing concentrations of PPQ (n = 1). Parasites were treated either only with 500 nM DHA or the combination of DHA and PPQ in a 10-fold dilution gradient. …”

Table_1_Serum Soluble Mediator Profiles and Networks During Acute Infection With Distinct DENV Serotypes.docx by Mikelly Santos Coutinho-da-Silva (12692609)

“…The substantial increase (≥10-fold) of CXCL10, IL-6, and IFN-γ, and decreased levels of PDGF (<0.4-fold) was universally identified in all DENV serotypes. …”

Effects of Synthetic N-Terminal 17-Residue Peptide on the Δ2–17 MthK Channels by Mario Meng-Chiang Kuo (376172)

“…<div><p>(A) A single-channel trace (top) shows that the channel open probability decreases when 10 μM synthetic peptide (aa1–17) was added to the perfusate (red bar). …”

Formation of meristemoids, guard mother cells, and stomata in the wild type and er pedicels. by Mark G. R. Bundy (132182)

“…Data points represent the fraction of a cell type in an individual pedicel. …”

La protein expression promotes proliferation and cell cycle progression of SCC 22B cells. by Gunhild Sommer (13580)

“…<p><b>(A)</b> Lower La expression in siRNA-mediated SCC 22B cells (see Western blot analysis in inlet) correlates with decreased proliferation rate (dotted line). …”

Choroidal vascularity changes in idiopathic central serous chorioretinopathy after half-fluence photodynamic therapy by Dae Joong Ma (5687885)

“…The vascular proportions in Sattler’s and Haller’s layers did not show a significant decrease at 6 weeks (Sattler’s: 49.7% ± 17.3%, <i>P</i> = 0.052 and Haller’s: 58.3% ± 12.9%, <i>P</i> = 0.558) but decreased significantly at 6 months (Sattler’s: 48.9% ± 12.4%, <i>P</i> < 0.001 and Haller’s: 57.7% ± 15.7%, <i>P</i> = 0.027) and 12 months after HF-PDT from the baseline values (Sattler’s: 45.8% ± 10.4%, <i>P</i> < 0.001 and Haller’s: 56.8% ± 15.7%, <i>P</i> < 0.001).…”

Effects of BT on gastrointestinal motility. by Wei-Yi Wu (1785187)

“…S, Stomach; A, appendix. Only 5 BT decreased gastrointestinal transit. …”

Mutant huntingtin actions on GABAA receptors and NMDA receptors by Alison Twelvetrees (467856)

Figure 3 by Feng Bai (336697)

“…Thresholds were set at a corrected <i>P</i><0.05, determined by Monte Carlo simulation. (3) Overlap regions (PCC/Pcu) between baseline changes and longitudinal changes of DMN IC were observed in aMCI group compared to controls. (4) Hyper-functional connectivity between the PCC/PCu (overlap regions) and mean DMN IC in baseline aMCI subjects, and significant hypo-connections of these regions were in follow-up aMCI subjects, whilst controls only showed a light decreases at the longitudinal period. * <i>P</i><0.05 (0.046); ** <i>P</i><0.001(0.000). (5) Correlative analysis: within the aMCI group, the decreases of functional connectivity between PCC/PCu and mean DMN IC were positively related to the impairments of episodic memory (AVLT-delayed recall scores, r = 0.462, <i>P</i> = 0.018, two-tailed) from baseline to follow up. …”

Increased cellular protein modification by methylglyoxal activates endoplasmic reticulum-based sensors of the unfolded protein response by Xue, Mingzhan

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Silibinin improves palmitate-induced insulin resistance in C2C12 myotubes by attenuating IRS-1/PI3K/Akt pathway inhibition by H.B. Li (6514220)

Titration and characteristics of pressure-support ventilation use in Argentina: an online cross-sectional survey study by Joaquin Pérez (10437650)

Graphene oxide nanoparticles induce hepatic dysfunction through the regulation of innate immune signaling in zebrafish (<i>Danio rerio</i>) by Guanghua Xiong (8543577)

Androgen receptor gene deficiency results in the reduction of steroidogenic potential in porcine luteal cells by Jaya Bharati (12843349)

Effects of TO901317 on apoptosis. by Irene Paterniti (310894)

“…<p>The results underlined that Bax expression was considerably enhanced in the MPTP group (b, b1 see densitometry analysis g, and Figure b in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0174470#pone.0174470.s005" target="_blank">S5 File</a>) whereas treatment with TO901317 significantly limited the rise in Bax expression (c,c1 see densitometry analysis g and Figure c in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0174470#pone.0174470.s005" target="_blank">S5 File</a>). …”

Influenza prevalence and vaccine efficacy among diabetic patients in Qatar by Swapna, Thomas

“…Among the typed IVA-positive cases, 33.4% were H1N1, and 7.7% were H3N2. A significant decrease in influenza infections was reported in vaccinated DM patients (14.5%) when compared to non-vaccinated patients (18.9%) (p-value = 0.006). …”
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C6-ceramide nanoliposomes target GAPDH in CLL. by Lindsay K. Ryland (499850)

“…Densitometry analysis from replicate experiments (n=4) was performed via ImageJ software. In Figure A(ii) the representative blot demonstrates a decrease in GAPDH at 12.5µM C6-ceramide, a result not observed in the other two distinct replicate experiments. * <i>P</i> < 0.05; ** <i>P <0 .005</i>. …”

Data_Sheet_1_One Century of Forest Monitoring Data in Switzerland Reveals Species- and Site-Specific Trends of Climate-Induced Tree Mortality.docx by Sophia Etzold (6496022)

“…However, tree mortality at the ecosystem level remains challenging to quantify since long-term, tree-individual, reliable observations are scarce. Here, we present a unique data set of monitoring records from 276 permanent plots located in 95 forest stands across Switzerland, which include five major European tree species (Norway spruce, Scots pine, silver fir, European beech, and sessile and common oak) and cover a time span of over one century (1898–2013), with inventory periods of 5–10 years. …”

Analysis of WT and <i>Abl</i> neuronal growth at RT and HT. by Lijuan Liu (136685)

“…Neurons in Abl cultures show a greater number of filopodia at RT than WT but show a significant decrease in filopodial numbers following HT incubation (cell clusters numbers: WT RT, 74; WT HT, 66; Abl RT, 72; Abl HT, 102, respectively, **p<0.01, unpaired T-test). …”