Protein Quality Control Disruption by PKCβII in Heart Failure; Rescue by the Selective PKCβII Inhibitor, βIIV5-3 by Julio C. B. Ferreira (145311)

“…Importantly, inhibition of PKCβII, using a selective PKCβII peptide inhibitor (βIIV5-3), improved proteasomal activity and conferred protection in cultured neonatal cardiomyocytes. …”

Data_Sheet_1_Map2k5-Deficient Mice Manifest Phenotypes and Pathological Changes of Dopamine Deficiency in the Central Nervous System.ZIP by Yumeng Huang (591166)

“…Furthermore, Map2k5 mutant mice showed a decreased dopaminergic cell survival and tyrosine hydroxylase levels in nigrostriatal pathway, indicating a crucial role of MAP2K5 in regulating dopamine system in the central nervous system. …”

Direct recruitment of polarity factors to the patch enables highly mobile clusters. by Samuel A. Ramirez (4951921)

“…<b>(C)</b> Patch diffusivities as a function of total GEF for simulations where <i>k</i>_<i>2b</i> has been decreased by a factor of 1/16 and <i>k</i>_<i>5a</i> has been increased by a factor of 10 relative to the parameters in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1008525#pcbi.1008525.t001" target="_blank">Table 1</a>. …”

Image_3_Phosphodiesterase Type 5 Inhibitors Synergize Vincristine in Killing Castration-Resistant Prostate Cancer Through Amplifying Mitotic Arrest Signaling.TIF by Jui-Ling Hsu (515080)

“…Sildenafil, a specific phosphodiesterase type 5 (PDE5) inhibitor, has been suggested to display both cardioprotective and neuroprotective activities that provide a rationale for the combination with vincristine on the treatment against castration-resistant prostate cancer (CRPC). …”

Image_2_Phosphodiesterase Type 5 Inhibitors Synergize Vincristine in Killing Castration-Resistant Prostate Cancer Through Amplifying Mitotic Arrest Signaling.TIF by Jui-Ling Hsu (515080)

“…Sildenafil, a specific phosphodiesterase type 5 (PDE5) inhibitor, has been suggested to display both cardioprotective and neuroprotective activities that provide a rationale for the combination with vincristine on the treatment against castration-resistant prostate cancer (CRPC). …”

Image_4_Phosphodiesterase Type 5 Inhibitors Synergize Vincristine in Killing Castration-Resistant Prostate Cancer Through Amplifying Mitotic Arrest Signaling.TIF by Jui-Ling Hsu (515080)

“…Sildenafil, a specific phosphodiesterase type 5 (PDE5) inhibitor, has been suggested to display both cardioprotective and neuroprotective activities that provide a rationale for the combination with vincristine on the treatment against castration-resistant prostate cancer (CRPC). …”

Image_1_Phosphodiesterase Type 5 Inhibitors Synergize Vincristine in Killing Castration-Resistant Prostate Cancer Through Amplifying Mitotic Arrest Signaling.TIF by Jui-Ling Hsu (515080)

“…Sildenafil, a specific phosphodiesterase type 5 (PDE5) inhibitor, has been suggested to display both cardioprotective and neuroprotective activities that provide a rationale for the combination with vincristine on the treatment against castration-resistant prostate cancer (CRPC). …”

Image_7_ARID5B regulates fatty acid metabolism and proliferation at the Pre-B cell stage during B cell development.tif by Jaya Prakash Chalise (16506906)

“…Dysregulation of this process may result in the failure to produce functional B cells and pose a risk of leukemic transformation. Here, we report that AT rich interacting domain 5B (ARID5B), a B cell acute lymphoblastic leukemia (B-ALL) risk gene, regulates B cell development at the Pre-B stage. …”

Image_2_ARID5B regulates fatty acid metabolism and proliferation at the Pre-B cell stage during B cell development.tif by Jaya Prakash Chalise (16506906)

“…Dysregulation of this process may result in the failure to produce functional B cells and pose a risk of leukemic transformation. Here, we report that AT rich interacting domain 5B (ARID5B), a B cell acute lymphoblastic leukemia (B-ALL) risk gene, regulates B cell development at the Pre-B stage. …”

Image_10_ARID5B regulates fatty acid metabolism and proliferation at the Pre-B cell stage during B cell development.tif by Jaya Prakash Chalise (16506906)

“…Dysregulation of this process may result in the failure to produce functional B cells and pose a risk of leukemic transformation. Here, we report that AT rich interacting domain 5B (ARID5B), a B cell acute lymphoblastic leukemia (B-ALL) risk gene, regulates B cell development at the Pre-B stage. …”

Image_6_ARID5B regulates fatty acid metabolism and proliferation at the Pre-B cell stage during B cell development.tif by Jaya Prakash Chalise (16506906)

“…Dysregulation of this process may result in the failure to produce functional B cells and pose a risk of leukemic transformation. Here, we report that AT rich interacting domain 5B (ARID5B), a B cell acute lymphoblastic leukemia (B-ALL) risk gene, regulates B cell development at the Pre-B stage. …”

Image_4_ARID5B regulates fatty acid metabolism and proliferation at the Pre-B cell stage during B cell development.tif by Jaya Prakash Chalise (16506906)

“…Dysregulation of this process may result in the failure to produce functional B cells and pose a risk of leukemic transformation. Here, we report that AT rich interacting domain 5B (ARID5B), a B cell acute lymphoblastic leukemia (B-ALL) risk gene, regulates B cell development at the Pre-B stage. …”

Image_1_ARID5B regulates fatty acid metabolism and proliferation at the Pre-B cell stage during B cell development.tif by Jaya Prakash Chalise (16506906)

“…Dysregulation of this process may result in the failure to produce functional B cells and pose a risk of leukemic transformation. Here, we report that AT rich interacting domain 5B (ARID5B), a B cell acute lymphoblastic leukemia (B-ALL) risk gene, regulates B cell development at the Pre-B stage. …”

Image_9_ARID5B regulates fatty acid metabolism and proliferation at the Pre-B cell stage during B cell development.tif by Jaya Prakash Chalise (16506906)

“…Dysregulation of this process may result in the failure to produce functional B cells and pose a risk of leukemic transformation. Here, we report that AT rich interacting domain 5B (ARID5B), a B cell acute lymphoblastic leukemia (B-ALL) risk gene, regulates B cell development at the Pre-B stage. …”

Image_3_ARID5B regulates fatty acid metabolism and proliferation at the Pre-B cell stage during B cell development.tif by Jaya Prakash Chalise (16506906)

“…Dysregulation of this process may result in the failure to produce functional B cells and pose a risk of leukemic transformation. Here, we report that AT rich interacting domain 5B (ARID5B), a B cell acute lymphoblastic leukemia (B-ALL) risk gene, regulates B cell development at the Pre-B stage. …”

Table_1_ARID5B regulates fatty acid metabolism and proliferation at the Pre-B cell stage during B cell development.pdf by Jaya Prakash Chalise (16506906)

“…Dysregulation of this process may result in the failure to produce functional B cells and pose a risk of leukemic transformation. Here, we report that AT rich interacting domain 5B (ARID5B), a B cell acute lymphoblastic leukemia (B-ALL) risk gene, regulates B cell development at the Pre-B stage. …”

Table_2_ARID5B regulates fatty acid metabolism and proliferation at the Pre-B cell stage during B cell development.pdf by Jaya Prakash Chalise (16506906)

“…Dysregulation of this process may result in the failure to produce functional B cells and pose a risk of leukemic transformation. Here, we report that AT rich interacting domain 5B (ARID5B), a B cell acute lymphoblastic leukemia (B-ALL) risk gene, regulates B cell development at the Pre-B stage. …”

Table_5_Transcriptome of Two Canine Prostate Cancer Cells Treated With Toceranib Phosphate Reveals Distinct Antitumor Profiles Associated With the PDGFR Pathway.DOCX by Priscila E. Kobayashi (9693758)

Image_8_ARID5B regulates fatty acid metabolism and proliferation at the Pre-B cell stage during B cell development.tif by Jaya Prakash Chalise (16506906)

“…Dysregulation of this process may result in the failure to produce functional B cells and pose a risk of leukemic transformation. Here, we report that AT rich interacting domain 5B (ARID5B), a B cell acute lymphoblastic leukemia (B-ALL) risk gene, regulates B cell development at the Pre-B stage. …”

Image_1_Soluble Neuropilin-1 Response to Hypoglycemia in Type 2 Diabetes: Increased Risk or Protection in SARS-CoV-2 Infection?.tif by Abu Saleh Md Moin (6189512)

“…Introduction<p>Neuropilin-1(NRP1) is a cofactor that enhances SARS-CoV-2 coronavirus cell infectivity when co-expressed with angiotensin-converting enzyme 2(ACE2). …”