Loss of b-cell K_ATP reduces Ca²⁺ sensitivity of insulin secretion and <i>Trpm5</i> expression by Nathaniel W. York (20410828)

“…However, this was not as severe as in WT animals, which suggests that decreased expression of <i>Trpm5</i> may play a small role in the disruption of insulin secretion with K_ATP loss.…”

Three general explanations for greater complexity associated with pollinator networks derived from metabarcoding. by Katherine A. Arstingstall (15314602)

Anisotropic Tuning of Graphite Thermal Conductivity by Lithium Intercalation by Xin Qian (714942)

“…We found that intercalation of lithium has an anisotropic effect on tuning the thermal conductivity: the thermal conductivity in the basal plane decreases monotonically from 1232 W/m·K of pristine graphite to 444 W/m·K of the fully lithiated LiC₆, while the thermal conductivity along the <i>c</i>-axis decreases first from 6.5 W/m·K for graphite to 1.3 W/m·K for LiC₁₈ and then increases to 5.0 W/m·K for LiC₆ as the lithium composition increases. …”

Data Sheet 1_Human and predator presence shape diel activity of urban red squirrels.pdf by Sinah Drenske (13191534)

“…Predator presence affected timing of activity, decreasing total daily activity. Pets, like cats, decreased activity at both resolutions, while martens had a limited effect detected only at the hourly resolution. …”

Data Sheet 5_Yunvjian decoction attenuates lipopolysaccharide-induced acute lung injury by inhibiting NF-κB/NLRP3 pathway and pyroptosis.docx by Fanxuan Zhang (20611100)

Data_Sheet_1_Loud noise-exposure changes the firing frequency of subtypes of layer 5 pyramidal neurons and Martinotti cells in the mouse auditory cortex.docx by Ingrid Nogueira (15407156)

“…</p>Methods<p>Here we compare membrane properties of layer 5 (L5) pyramidal cells (PCs) and Martinotti cells expressing the cholinergic receptor nicotinic alpha 2 subunit gene (Chrna2) of the primary auditory cortex (A1) from control and noise-exposed (4–18 kHz, 90 dB, 1.5 h, followed by 1.5 h silence) 5–8 week old mice. …”

Data_Sheet_1_Cell-permeable peptide nucleic acid antisense oligonucleotide platform targeting human betacoronaviruses.pdf by Soree Park (790312)

“…</p>Results<p>NSP 14 targeting OPNA 5 and 11, reduced the viral titer to a half and OPNA 530, 531 and 533 lowered viral gene expression levels to less than 50% of control by targeting the 5’ UTR region. …”

Generated dynamics for the fourth simulation ‘Cooling of HVC’: We simulated two cooling experiments, where the format is the same as in <b>Figure 5</b> with arbitrary units. by Izzet B. Yildiz (191749)

“…The change in slows down the dynamics of the system, while cooling at the RA level does not have any significant effect, compare with the dynamics in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1002303#pcbi-1002303-g005" target="_blank">Figure 5</a>. …”

Supplementary Material for: M1 Macrophages Increase Endothelial Permeability and Enhance p38 Phosphorylation via PPAR-γ/CXCL13-CXCR5 in Sepsis by Chen W. (2828783)

“…<b><i>Conclusion:</i></b> M1 macrophages induced endothelial hyperpermeability and promoted p38 phosphorylation in sepsis by inhibiting PPAR-γ to increase CXCL13 production. PPAR-γ/CXCL13-CXCR5 signaling could be a promising novel therapeutic target for sepsis.…”

Expression and secretion of the ManB-SlpA fusion protein in <i>L</i>. <i>casei</i> MCJΔ1/ pELWH-ManB. by Jinzhong Lin (189430)

“…The mannanase activity increased during the early growth phase, peaking at OD₆₀₀ = 3.7 with an activity of 28.4 mU·5×10⁹ cfu^-1, and then decreased. …”

Acute D3 treatment conveys STM impairment that mainly affects hippocampal-dependent spatial memory consolidation. by Sylvia Josephy-Hernandez (6871478)

“…<p><b>(A)</b> Mice were trained in the Morris Water Maze (MWM) with three trials per day for 5 consecutive days. …”

Performance indices measured at multiple times after conditioning CS flies at 20, 30, and 40 days of age compared to control 5-day-old flies. by Rodrigo Pacifico (6111578)

Table5_Computational approaches for discovering significant microRNAs, microRNA-mRNA regulatory pathways, and therapeutic protein targets in endometrial cancer.XLSX by Ghada Ajabnoor (404336)

Presentation_1_Deciphering the Mechanism of Inhibition of SERCA1a by Sarcolipin Using Molecular Simulations.pdf by Thomas Barbot (10095796)

“…Sarcolipin (SLN), a transmembrane peptide, regulates the activity of SERCA1a by decreasing its Ca²⁺ transport rate, but its mechanism of action is still not well-understood. …”

Presentation_1_Deciphering the Mechanism of Inhibition of SERCA1a by Sarcolipin Using Molecular Simulations.pdf by Thomas Barbot (10095796)

“…Sarcolipin (SLN), a transmembrane peptide, regulates the activity of SERCA1a by decreasing its Ca²⁺ transport rate, but its mechanism of action is still not well-understood. …”

Presentation_1_Spermine Alleviates Acute Liver Injury by Inhibiting Liver-Resident Macrophage Pro-Inflammatory Response Through ATG5-Dependent Autophagy.PDF by Shun Zhou (5162975)

“…Knockdown of ATG5 in SPM-pretreated KCs by siRNA resulted in a significant increase in pro-inflammatory TNF-α and IL-6 secretion and decreased anti-inflammatory IL-10 secretion after TAA treatment, while no significant changes were observed in cytokine production in the TAA treatment alone. …”

Supplementary Figure S1 from Cellular Prion Protein PrP^C and Ecto-5′-Nucleotidase Are Markers of the Cellular Stress Response to Aneuploidy by Patrícia H. Domingues (14925828)

“…The expression of 291 cell surface markers (each row represents a single protein) in 5 different aneuploid cell lines (each column represents a different cell line, namely RPE1 5/3 12/3 - trisomy of chromosome 5 and 12 -, RPE1 21/3 - trisomy of chromosome 21 -, HCT116 5/3 - trisomy of chromosome 5 -, RPT1 - RPE1 post-tetraploid clone -, HPT1 - HCT116 post-tetraploid clone -) is shown in a matrix format. …”

Image_1_Guanylyl Cyclase A/cGMP Signaling Slows Hidden, Age- and Acoustic Trauma-Induced Hearing Loss.TIF by Philine Marchetta (8692149)

“…OHCs in these frequency regions in young GC-A knockout mice exhibited diminished levels of KCNQ4 expression, which is the dominant K⁺ channel in OHCs, and decreased activation of poly (ADP-ribose) polymerase-1, an enzyme involved in DNA repair. …”

Image5_Fatty acid metabolism prognostic signature predicts tumor immune microenvironment and immunotherapy, and identifies tumorigenic role of MOGAT2 in lung adenocarcinoma.tif by Denggang Fu (5082062)

“…</p>Methods<p>We developed a prognostic signature comprising 10 FAM-related genes (GPR115, SOAT2, CDH17, MOGAT2, COL11A1, TCN1, LGR5, SLC34A2, RHOV, and DKK1) using data from LUAD patients in The Cancer Genome Atlas (TCGA). …”

Heatmaps of predicted [<i>POA</i>_<i>T</i>]_<i>i</i> at 240 hours of simulation, for the five studied scenarios. by David Requena (498200)