Image_5_Combination of single-nucleus and bulk RNA-seq reveals the molecular mechanism of thalamus haemorrhage-induced central poststroke pain.tif by Tianfeng Huang (13896228)

Leveraging Peripheral CB1 Antagonism in 1,4,5,6-Tetrahydropyridazine-Based Amidine Substituted Sulfonyl Analogs for Treating Metabolic Disorders by Pinaki Bhattacharjee (11971366)

“…Initial synthesis included compounds <b>10a</b>–<b>u</b>, followed by expansion into distinct amidine groups <b>(11a–18e</b>) for detailed structure–activity relationships. …”

Leveraging Peripheral CB1 Antagonism in 1,4,5,6-Tetrahydropyridazine-Based Amidine Substituted Sulfonyl Analogs for Treating Metabolic Disorders by Pinaki Bhattacharjee (11971366)

“…Initial synthesis included compounds <b>10a</b>–<b>u</b>, followed by expansion into distinct amidine groups <b>(11a–18e</b>) for detailed structure–activity relationships. …”

Data_Sheet_1_Asthmatic Bronchial Smooth Muscle Increases CCL5-Dependent Monocyte Migration in Response to Rhinovirus-Infected Epithelium.docx by Benoit Allard (522753)

“…However, we demonstrated that CCL5 was further increased in the asthmatic BSM co-culture and that anti-CCL5 blocking antibody significantly decreased monocyte migration induced by HRV-infected BE. …”

The 5′ Flanking Region and Intron1 of the Bovine Prion Protein Gene (<em>PRNP</em>) Are Responsible for Negative Feedback Regulation of the Prion Protein by Guangai Xue (179316)

“…The PrP-expressing plasmid pEF-boPrP and luciferase-expressing plasmids containing the partial promoter fragment of <em>PRNP</em> incorporating naturally occurring single-nucleotide or insertion/deletion polymorphisms were transfected into N2a cells. Transfection of pEF-boPrP induced PrP overexpression and decreased the promoter activity of <em>PRNP</em> in the wild-type haplotype (23-bp Del, 12-bp Del, and −47C). …”

Table_5_Maternal High-Protein and Low-Protein Diets Perturb Hypothalamus and Liver Transcriptome and Metabolic Homeostasis in Adult Mouse Offspring.XLSX by Lisa J. Martin (228675)

“…Perinatal HP/LC and LP/HC exposures resulted in a decreased ability to clear glucose in the offspring, with reduced baseline insulin and glucose concentrations in the LP/HC group and a reduced insulin response post-glucose challenge in the HP/LC group. …”

Image_5_Function and Mechanism of Trimetazidine in Myocardial Infarction-Induced Myocardial Energy Metabolism Disorder Through the SIRT1–AMPK Pathway.JPEG by Xiu-ying Luo (10984614)

“…The current study set out to evaluate the effect and mechanism of TMZ on MEM disorder induced by myocardial infarction (MI). Firstly, a MI mouse model was established by coronary artery ligation, which was then treated with different concentrations of TMZ (5, 10, and 20 mg kg^–1 day^–1). …”

Image_5_Underwater Acoustic Ecology Metrics in an Alaska Marine Protected Area Reveal Marine Mammal Communication Masking and Management Alternatives.PNG by Christine M. Gabriele (3297708)

“…RA was approximated from the quietest 5th percentile noise statistics based on a year (2011) of continuous audio data from a hydrophone in GBNP, in the frequency bands of whale and seal sounds of interest: humpback “whup” calls (50–700 Hz, 143 dB re 1 μPa source level, SL); humpback song (224–708 Hz, 175 dB SL), and harbor seal roars (4–500 Hz, 144 dB SL). …”

Supplementary Revised Figure S2 from MUC16 Regulates TSPYL5 for Lung Cancer Cell Growth and Chemoresistance by Suppressing p53 by Imayavaramban Lakshmanan (281140)

Image_5_ATF3 Sustains IL-22-Induced STAT3 Phosphorylation to Maintain Mucosal Immunity Through Inhibiting Phosphatases.JPEG by Doaa Glal (5927738)

Supplementary Revised Figure S3 from MUC16 Regulates TSPYL5 for Lung Cancer Cell Growth and Chemoresistance by Suppressing p53 by Imayavaramban Lakshmanan (281140)

“…<p>Chemoresistance properties of MUC16 and effect of cisplatin on apoptosis of MUC16 knockdown cells. A & B, MUC16 knockdown (H1975-shMUC16 seq1 and 2) cells were highly sensitive to cisplatin (A) and gemcitabine (B). …”

datasheet5_Using Machine Learning to Make Computationally Inexpensive Projections of 21st Century Stratospheric Column Ozone Changes in the Tropics.csv by James Keeble (3595139)

“…All four techniques investigated here are able to make projections of future tropical stratospheric column ozone which agree well with those made by the UKESM1 Earth system model, often falling within the ensemble spread of UKESM1 simulations for a broad range of SSPs. However, all techniques struggle to make accurate projects for the final decades of the SSP5-8.5 scenario. …”

Image_5_Limbic oxytocin receptor expression alters molecular signaling and social avoidance behavior in female prairie voles (Microtus ochrogaster).TIF by Lina K. Nerio-Morales (19142107)

Image_5_ACO1 and IREB2 downregulation confer poor prognosis and correlate with autophagy-related ferroptosis and immune infiltration in KIRC.tiff by Ting Zhu (460268)

Table_5_Last-Generation Genome–Environment Associations Reveal the Genetic Basis of Heat Tolerance in Common Bean (Phaseolus vulgaris L.).xlsx by Felipe López-Hernández (7911326)

The Effect of Rosuvastatin in a Murine Model of Influenza A Infection by Kathryn A. Radigan (169555)

“…We hypothesized that rosuvastatin would decrease viral replication, attenuate lung injury, and improve mortality following influenza A infection in mice.…”

Image_5_Immune activation of characteristic gut mycobiota Kazachstania pintolopesii on IL-23/IL-17R signaling in ankylosing spondylitis.tif by Haiting Zhang (3618731)

Table_5_RNA-Seq Analyses of Midgut and Fat Body Tissues Reveal the Molecular Mechanism Underlying Spodoptera litura Resistance to Tomatine.DOCX by Qilin Li (535447)

Image_5_Follicular regulatory T cells eliminate HIV-1-infected follicular helper T cells in an IL-2 concentration dependent manner.tif by Matthew T. Ollerton (14065902)

“…We evaluated the hypothesis that TFR suppress HIV replication in TFH using a well-established model of ex vivo HIV infection that employs tonsil cells from HIV uninfected individuals spinoculated with CXCR4- and CCR5-tropic HIV-GFP reporter viruses. …”

Image 5_Integrative bulk and single-cell transcriptome analyses reveal integrated stress response-related biomarkers in periodontitis with experimental validation.tif by Linling Du (22827035)