ScFv 2LF dissociation rate constants with each LF variant, measured by Biacore experiments. by Philippe Thullier (320909)

“…<p>The five residues whose mutation to alanine resulted in a 3-fold, or larger, decrease of the dissociation constant are shown in bold.…”

File S1 - Budding Yeast Kinetochore Proteins, Chl4 and Ctf19, Are Required to Maintain SPB-Centromere Proximity during G1 and Late Anaphase by Soumitra Sau (594397)

“…A large spatial fluctuation (∼±300 nm) about the mean KT position is observed for ς ∼5 pN-µm/s. …”

Neurotrophic factor gene profile of E14 spinal cord derived-progenitor cells during differentiation <i>in vitro.</i> by Masaya Nakamura (121832)

“…<p>After 2–4 passages, cells were seeded on the PEI-coated culture flasks at a density of 2×10⁵ cells/ml in the differentiation medium (no EGF/FGF2, 1% FBS). …”

WNV infection of HMBVE cells, but not of leukocytes, mediates the disruption of the <i>in vitro</i> BBB model. by Kelsey Roe (309298)

“…<p>The effect of leukocyte migration on the permeability of the <i>in vitro</i> BBB model was determined by TEER measurements. (<b>A)</b> WNV infected monocytes (2.5 x 10⁵) at 24 hrs after infection were added in the upper compartment of the uninfected BBB model and permeability was measured at 2 and 4 hrs after incubation. …”

Pirt contributes to histaminergic itch. by Kush N. Patel (350598)

“…<p>(<b>A</b>) The time course shows scratching bouts, presented as mean ± SEM, in response to histamine injection (10 µmol) over a 30 min period divided into 5 min intervals. …”

Proinflammation. by Ying Sun (23237)

“…(E) TNFα and IL-6 mRNA in midbrain was determined by qRT-PCR. …”

Supplementary Material for: Human Oral Mucosal Stem Cells Reduce Anastomotic Leak in an Animal Model of Colonic Surgery by Kent I. (10699344)

“…The objective of this study was to evaluate whether hOMSC can decrease anastomotic leak rates in a murine model of colon surgery. …”

<i>as-</i>APF downregulates MDM2, leading to inhibition of cell proliferation. by Jayoung Kim (153487)

“…Protein extracts were prepared from growing TRT-HU1, RT4 and T24 bladder cell lines for western blot analysis using antibodies against MDM2, p53 and β-actin. (<b>B</b>) MDM2, an E3 ubiquitin ligase, is decreased in response to <i>as-</i>APF. …”

Phenolic contents-based assessment of therapeutic potential of Syzygium cumini leaves extract by Ahmed, Rashid

“…The leaf extract also demonstrated an analgesic effect in rabbits as indicated by the decrease in writhing (12.2 ± 1.7 control vs. 3.7 ± 0.6 treated) and anti-inflammatory activity in rabbits paw with a protection against inflammation of 64.1 ± 2.4%. …”
Get full text
Get full text

Effects of the P20 protein from Bacillus thuringiensis israelensis on insecticidal crystal protein Cry4Ba by Jaoua, Samir

“…Cry4BLB crystals produced in the presence of P20 were much less soluble than those produced by the control strain lacking P20 at pH lower than or equal to 10.5. The observed toxicity perturbation correlates with a decrease of Cry4BLB inclusions solubility. …”
Get full text
Get full text

Experimental studies on the biodiesel production parameters optimization of sunflower and soybean oil mixture and DI engine combustion, performance, and emission analysis fueled wi... by Elkelawy M.

“…70% biodiesel) were prepared to power a single cylinder diesel engine. The engine results as compared to diesel fuel, show a reduction in the rate of change of CO by 33.8% for D50B50. …”
Get full text
Get full text

Impacts of Human Disturbance on Large Prey Species: Do Behavioral Reactions Translate to Fitness Consequences? by Mathieu Leblond (457233)

“…We hypothesized that human activities and infrastructure cause a decrease in the individual performance of preys because of anthropogenically enhanced predation risk. …”

M-cells are depleted with αRANKL antibody treatment. by Aimee L. Cunningham (650204)

“…<p>BALB/c mice (n = 3 per group) were treated i.p. with 250 μg of either rat Ig (a-b) or αRANKL antibody IK22-5 (c-d) on days 0, 2, 4, and 6. …”

Igf signaling is required for contribution of<i>gata4:EGFP</i> positive cardiomyocytes to the regenerating area. by Ying Huang (53474)

“…<p><i>gata4:EGFP</i> fish were treated with the Igf1r inhibitor NVP-AEW541 from 2–14 dpa (n = 12) (B, D) and 7–10 dpa (n = 5) (F, H). DMSO was used as a control (14dpa: n = 10; 10 dpa: n = 6) (A, C, E, G). …”

N-acetylcysteine Protects against Apoptosis through Modulation of Group I Metabotropic Glutamate Receptor Activity by Lili Sun (162122)

“…In this study, we investigated the effects of N-acetylcysteine (NAC), a precursor of the antioxidant glutathione, on group I mGlus activation in apoptosis of glial C6 and MN9D cell lines, and a rat model of Parkinson's disease (PD). …”

Regulation of autophagy, mitochondrial dynamics, and cellular bioenergetics by 4-hydroxynonenal in primary neurons by Matthew Dodson (4388749)

“…Finally, inhibition of autophagy initiation using 3-methyladenine (3MA) also results in a significant decrease in mitochondrial function and network length. …”

Evaluation of Pelleting Mealworm (Tenebrio Molitor) Powder with Chokeberry By-product Meal To improve Duck Production and Meat Quality Traits by IH Choi (5838176)

“…<div><p>ABSTRACT This study aimed to evaluate the effects of dietary supplementation pelleted Tenebrio molitor (TM) powder with chokeberry by-product (CBP) meal on duck production and meat quality traits. A total of 180 0-day-old Pekin ducks were allocated randomly between three dietary groups viz., control, Treatment 1, and Treatment 2, with three pens per group and twenty birds per pen, characterized by increasing levels of pelleted TM powder with CBP meal in concentration of 0%, 1.5%, and 3%, respectively, and reared until 42 days of age in a completely randomized design. …”

Induction of VE-cadherin proteolytic cleavage by <i>P. aeruginosa</i> T2SS. by Guillaume Golovkine (534765)

“…Protein extracts were analyzed by Western blotting with VE-cadherin (BV9) and ß-tubulin antibodies. Data show a decrease in VE-cadherin levels, occurring in infected cells even in absence of the T3 effectors. …”

Regional ventilation distribution. by Günther Zick (20626)

“…No obvious difference between ventilation with 10 ml/kg V_T and inactive interventional lung assist (ILA) (high V_T, no ILA) and ventilation with 5 ml/kg V_T and active ILA (low V_T, ILA) was detected. …”

Geochemistry and zircon U-Pb geochronology of Miocene plutons in the Urumieh-Dokhtar magmatic arc, east Tafresh, Central Iran by Davood Raeisi (6586937)

“…Geochemical signatures of Tafresh plutonic rocks, such as a wide range of Y/Nb (2.7–8.4) and low Zr/Nb (19.5–35.) ratios, Nb/Ta (11.46–18.15), argue for mantle–crust interaction during generation of Tafresh magmas. …”