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point decrease » point increase (Expand Search)
fold decrease » fold increase (Expand Search), fold increased (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
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18681
Image_5_Reductive Power Generated by Mycobacterium leprae Through Cholesterol Oxidation Contributes to Lipid and ATP Synthesis.tif
Published 2021“…LDs are promptly recruited to M. leprae-containing phagosomes, and inhibition of this process decreases bacterial survival, suggesting that LD recruitment constitutes a mechanism by which host-derived lipids are delivered to intracellular M. leprae. …”
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18682
Image_5_Reductive Power Generated by Mycobacterium leprae Through Cholesterol Oxidation Contributes to Lipid and ATP Synthesis.tif
Published 2021“…LDs are promptly recruited to M. leprae-containing phagosomes, and inhibition of this process decreases bacterial survival, suggesting that LD recruitment constitutes a mechanism by which host-derived lipids are delivered to intracellular M. leprae. …”
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18683
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18684
Image_4_Periplasmic Expression of 4/7 α-Conotoxin TxIA Analogs in E. coli Favors Ribbon Isomer Formation – Suggestion of a Binding Mode at the α7 nAChR.png
Published 2019“…Interestingly, in the case of the α7 nAChR, but not the α3β2 subtype, the loss of potency could be rescued by an R5D substitution. In conclusion, we demonstrate efficient expression of functional but alternatively folded ribbon TxIA variants in E. coli and provide the first structure–function analysis for a ribbon 4/7-α-conotoxin at α7 and α3β2 nAChRs. …”
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18685
Image_2_Periplasmic Expression of 4/7 α-Conotoxin TxIA Analogs in E. coli Favors Ribbon Isomer Formation – Suggestion of a Binding Mode at the α7 nAChR.JPEG
Published 2019“…Interestingly, in the case of the α7 nAChR, but not the α3β2 subtype, the loss of potency could be rescued by an R5D substitution. In conclusion, we demonstrate efficient expression of functional but alternatively folded ribbon TxIA variants in E. coli and provide the first structure–function analysis for a ribbon 4/7-α-conotoxin at α7 and α3β2 nAChRs. …”
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18686
Image_1_Periplasmic Expression of 4/7 α-Conotoxin TxIA Analogs in E. coli Favors Ribbon Isomer Formation – Suggestion of a Binding Mode at the α7 nAChR.JPEG
Published 2019“…Interestingly, in the case of the α7 nAChR, but not the α3β2 subtype, the loss of potency could be rescued by an R5D substitution. In conclusion, we demonstrate efficient expression of functional but alternatively folded ribbon TxIA variants in E. coli and provide the first structure–function analysis for a ribbon 4/7-α-conotoxin at α7 and α3β2 nAChRs. …”
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18687
Image_3_Periplasmic Expression of 4/7 α-Conotoxin TxIA Analogs in E. coli Favors Ribbon Isomer Formation – Suggestion of a Binding Mode at the α7 nAChR.JPEG
Published 2019“…Interestingly, in the case of the α7 nAChR, but not the α3β2 subtype, the loss of potency could be rescued by an R5D substitution. In conclusion, we demonstrate efficient expression of functional but alternatively folded ribbon TxIA variants in E. coli and provide the first structure–function analysis for a ribbon 4/7-α-conotoxin at α7 and α3β2 nAChRs. …”
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18688
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18689
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18690
Cell-targeted transgenic control of 5HT<sub>2A</sub>R levels in neurons and glia during the experience-dependent critical period.
Published 2024“…Two-way ANOVA with Tukey’s multiple comparison shows EB experience-dependent increase in 5HT<sub>2A</sub> receptor levels in both transgenic controls (<i>n</i> = 10 each, <i>repo-</i>Gal4<i>; p</i> = 5.38 × 10<sup>−10</sup>, <i>elav</i>-Gal4; <i>p</i> = 0.0205), a significant decrease in 5HT<sub>2A</sub> receptor levels in both RNAi conditions (<i>n</i> = 10 each, <i>repo-</i>Gal4<i>; p</i> = 4.63 × 10<sup>−10</sup>, <i>elav-</i>Gal4; <i>p</i> = 1.05 × 10<sup>−9</sup>), and a significant elevated EB response with glial <i>5HT</i><sub><i>2A</i></sub><i>R</i> OE (<i>n</i> = 10/condition, <i>p</i> = 2.36 × 10<sup>−9</sup>). …”
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18691
Density of states for the Hamiltonian on the π-flux cubic lattice model for different values of the anisotropy parameter <em>a</em> (from top to bottom, <em>a</em> = 0, 0.5, 1)
Published 2013“…</strong> Density of states for the Hamiltonian on the π-flux cubic lattice model for different values of the anisotropy parameter <em>a</em> (from top to bottom, <em>a</em> = 0, 0.5, 1).…”
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18692
Effects of ablation of I1 neurons on modulation of the pumping rate by green light illumination at low intensity (A) The frequency of pumping before, during, and after light illumi...
Published 2017“…WT (N2): n = 3 worms, 17 trials; <i>unc-7</i>: n = 3 worms, 14 trials; <i>unc-31</i>: n = 3 worms, 15 trials; <i>unc-31;unc-7</i>: n = 3 worms, 15 trials; WT (N2), I1 ablation: n = 4 worms, 19 trials; <i>unc-31</i>, I1 ablation: n = 5 worms, 23 trials. (B) Relative pumping rate during the 10 s period after illumination was started as calculated from the data shown in (A). …”
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18693
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18694
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18695
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18696
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18697
CRISPRi knockdown of Lon protease to increase half-life.
Published 2018“…Bivariate scatter plots show P<sub><i>inaA</i></sub> and P<sub><i>acrAB</i></sub> expression levels at the final time point across n = 5 microcolonies. …”
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18698
Carbon Monoxide Releasing Molecule-A1 (CORM-A1) Improves Neurogenesis: Increase of Neuronal Differentiation Yield by Preventing Cell Death
Published 2016“…Still, CORM-A1 increased cell proliferation assessed by ki67 expression and also prevented cell death, which was followed by increased Bcl-2 expression, decreased levels of active caspase-3 and PI uptake. …”
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18699
Disjoining Pressure of Water in Nanochannels
Published 2021“…The disjoining pressure was found to be as high as ∼1.5 MPa while exponentially decreasing with increasing channel height. …”
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18700
OA alters fatty acid metabolism and organ dysfunction and improves sepsis outcome.
Published 2016“…<p>CPT1A –carnitine palmitoyltransferase 1A; PPAR–peroxisome proliferator-activated receptor, UCP2 –uncoupling protein 2; AMPK—5' AMP-activated protein kinase. …”