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point decrease » point increase (Expand Search)
fold decrease » fold increase (Expand Search), fold increased (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
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18821
Data_Sheet_1_Periplasmic Expression of 4/7 α-Conotoxin TxIA Analogs in E. coli Favors Ribbon Isomer Formation – Suggestion of a Binding Mode at the α7 nAChR.ZIP
Published 2019“…Interestingly, in the case of the α7 nAChR, but not the α3β2 subtype, the loss of potency could be rescued by an R5D substitution. In conclusion, we demonstrate efficient expression of functional but alternatively folded ribbon TxIA variants in E. coli and provide the first structure–function analysis for a ribbon 4/7-α-conotoxin at α7 and α3β2 nAChRs. …”
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18822
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18823
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18824
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18825
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18826
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18827
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18828
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18829
Image_5_A Fenton-like cation can improve arsenic trioxide treatment of sclerodermatous chronic Graft-versus-Host Disease in mice.tif
Published 2022“…In vivo, in a cGvHD mouse model, daily injections of ATO 2.5 µg/g + CuCl<sub>2</sub> 0.5 µg/g induce a decrease in lymphocyte activation and fibrosis that was equivalent to that induced by ATO 5 µg/g. …”
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18830
DataSheet1_High-Temperature Tribological Behavior of Al0.3Cr0.5Fe1.5Mn0.5Ni High-Entropy Alloys With Addition of Titanium and Carbon.PDF
Published 2022“…After high-temperature wear testing, the HEAs demonstrated exceptional oxidation resistance and a lower friction coefficient than M2 steel since the dense glazed layer on the surface of the HEAs served as a lubricant to decrease the friction coefficient, and protected the substrate from oxidation.…”
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18831
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18832
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18833
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18834
DataSheet_1_Methylation of SPRED1: A New Target in Acute Myeloid Leukemia.docx
Published 2022“…To determine the possible mechanism of SPRED1 methylation in AML, we performed in vitro experiments using THP-1 cells, as the latter showed the highest methylation level (determined by utilizing bisulfite modification) among the three AML cell lines we tested. When treated with 5-AZA and lentivirus transfection, upregulated SPRED1 expression, decreased cell proliferation, increased cell differentiation and apoptosis, and inactivated phosphorylated extracellular signal-regulated kinase (p-ERK) were detected in THP-1 cells. …”
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18835
A bis-sulphamoylated estradiol derivative induces ROS-dependent cell cycle abnormalities and subsequent apoptosis
Published 2017“…Our data shows that EMBS targets a pathway that leads to increased ROS production as an early event that culminates in G<sub>2</sub>/M arrest and apoptosis by means of JNK-signaling in cancer cells. …”
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18836
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18837
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18838
Heterozygous <i>E168d2/</i>+, <i>E168d2neo/</i>+ and <i>R90W/</i>+ mice have graded deficits in retinal function.
Published 2014“…(Relative to <i>WT</i>: *p<0.05; relative to <i>E168d2neo/+</i>: *‘p<0.05, brackets indicate all enclosed data points are significant). …”
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18839
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18840