Sorafenib enhanced expression of osteopontin, an AP-1 target gene, in human hepatoma cell lines. by Yuki Haga (764328)

“…<p>(A, B) Knockdown of c-Jun decreased expression of osteopontin after 48 hours of transfection into PLC/PRF/5 cells with siRNA against c-Jun (si-c-Jun) or si-control (si-C). …”

Mixed codes can be more reliable than pure codes for both PE and MSE, but different RF sizes are appropriate for each. by W. Jeffrey Johnston (8463480)

“…<b>E</b> Cumulative distribution functions for the squared errors made by the codes given in <b>B</b> and <b>C</b> at the grey dashed line. …”

CatWalk gait analysis. by Nitish D. Fagoe (2548675)

“…(G, H)</b> Stride length increased over the time course in C4 injured animals compared to shams while in T7 injured animals stride length was actually decreased at several time points. <b>(I, J)</b> Mean pixel intensity was not different in C4 lesioned animals <b>(I)</b> and largely unchanged in T7 lesioned animals <b>(J)</b>. …”

Tumour Necrosis Factor Alpha, Interferon Gamma and Substance P Are Novel Modulators of Extrapituitary Prolactin Expression in Human Skin by Ewan A. Langan (405804)

“…</i> This was studied in serum-free organ cultures of microdissected human scalp HFs and skin, i.e. excluding pituitary, neural and vascular inputs. …”

High 22G RNA levels are associated with low mRNA expression, compatible with silencing. by Alexandra Bezler (6316151)

“…<p>A) Mean normalized mRNA [<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1007905#pgen.1007905.ref055" target="_blank">55</a>] and 22G RNA reads detected in hermaphrodite and male gonads (data in 20 bins according to 22G RNA level; number of genes per bin: 4–1101 in hermaphrodites, 5–1343 in males; mean: solid line, outliers: circles). mRNA expression is globally decreased for the top 5% of genes (shaded area) with high levels of 22G RNA. …”

The TrkB was expressed in neurons in the injured brain and treatment with 7,8-dihydroxyflavone attenuated stretch-induced cytotoxicity and apoptosis in primary cultured neurons. by Chun-Hu Wu (306057)

“…<b>(E)</b> Western blot analysis of apoptosis-related proteins (cleaved caspase-3, Bcl-2, and Bax) shows that 5 µM DHF significantly decreased the cleaved caspase-3 level and the Bcl2/Bax ratio. …”

Differential sensitivity to PI3K/AKT pathway regulation is lost in isolated cancer cells. by Maria Laura Polo (364546)

“…Proliferation assay (³H-thymidine incorporation) in primary C4-HD (left) or C4-HI (right) cells incubated during the last 48 hrs with 0.01 µM MPA and 5, 10 and 20 µM PD98059 or LY294002. For the combined treatment, the inhibitor was used at a dose of 10 µM. …”

<i>In-silico</i> identification of fingerprint of pyrazolyl sulfonamide responsible for inhibition of <i>N</i>-myristoyltransferase using Monte Carlo method with index of ideality... by Ashwani Kumar (55732)

“…One QSAR model with best <math><msubsup><mrow><mi>R</mi></mrow><mrow><mi>calibration</mi></mrow><mrow><mn>2</mn></mrow></msubsup></math> = 0.8638 for split 2 was considered as the leading model. A greater value of cRp² <i>i.e.</i> 0.5 for all models in Y-randomization test showed the robustness of developed models. …”

Genetic analysis of CRISPR-Cas9 mediated re-sensitization of <i>K. michiganensis</i> (KM). by Thaysa Leite Tagliaferri (6371453)

“…Fold change <i><i>bla</i></i>_KPC gene expression. A significant reduction was observed in the re-sensitized cells KM^S likely due to a decrease in <i><i>bla</i></i>_KPC gene copy number, as seen in 3C. 3E. …”

Effect of SPARC on the modulation of ECM proteins in proliferating C2C12 cells. by Aicha Melouane (4530787)

“…Addition of SPARC induced collagen 1a1 expression, however, SPARC inhibition decreased it. …”

Single-Beat Noninvasive Imaging of Ventricular Endocardial and Epicardial Activation in Patients Undergoing CRT by Thomas Berger (72614)

“…Left ventricular propagation velocities were significantly decreased in CHF patients as compared to the control group (1.6±0.4 versus 2.1±0.5 m/sec; p<0.05). …”

Table_1_Representing true plant genomes: haplotype-resolved hybrid pepper genome with trio-binning.docx by Emily E. Delorean (17399242)

“…However, most genome assembly methods that have been used in plants result in a merged single sequence representation that is not a true biologically accurate representation of either haplotype within a diploid individual. …”

DataSheet_1_Representing true plant genomes: haplotype-resolved hybrid pepper genome with trio-binning.xlsx by Emily E. Delorean (17399242)

“…However, most genome assembly methods that have been used in plants result in a merged single sequence representation that is not a true biologically accurate representation of either haplotype within a diploid individual. …”

Estrogen Receptor inhibition prevents estradiol-17ß-d-glucuronide (E17G)-induced endocytic internalization of Abcb11 and Abcc2 in perfused rat liver. by Ismael R. Barosso (116985)

“…ICI (0.5 µM, 15 min previous to E17G) prevented the internalization of canalicular transporters, as illustrated by a control-like pattern of Abcb11 and Abcc2 distribution. …”

Clinical Cysticercosis epidemiology in Spain based on the hospital discharge database: What's new? by Zaida Herrador (635669)

“…From 1998 to 2008, an increasing trend in the number of CC hospitalizations was observed, decreasing afterwards, in parallel with a decrease in the external migration rate. …”

Table1_Left ventricular structure and function following renal sympathetic denervation in patients with HFpEF: an echocardiographic 9-year long-term follow-up.docx by Alexander Vogt (375813)

“…We found a significant reduction of the HFA-PEFF score from 5.48 ± 0.51 points at baseline to 4.33 ± 1.53 points at the 9-year follow-up (P < 0.01). …”

Image_1_Pioglitazone Improves Mitochondrial Organization and Bioenergetics in Down Syndrome Cells.tif by Nunzia Mollo (6891068)

“…These effects, together with a significant increase of basal ATP content and oxygen consumption rate, and a significant decrease of reactive oxygen species (ROS) production, provide strong evidence of an overall improvement of mitochondria bioenergetics in trisomic cells. …”

BMI and Lifetime Changes in BMI and Cancer Mortality Risk by Niloofar Taghizadeh (724983)

“…Both short-term annual increase and decrease in BMI were associated with a lower mortality risk from any cancer [all subjects: (0.67 (0.47-0.94)) and (0.73 (0.55-0.97)), respectively]. …”

Table_1_Fish kills and insecticides: historical water quality patterns in 10 agricultural watersheds in Prince Edward Island, Canada (2002–2022).PDF by Miranda Crawford (14683993)

“…The changing climate significantly adds to the complexity of monitoring these systems as the regional rate of change is exceptionally high (e.g., a 0.70°C to 1.14°C increase in air temperature and 5–8% decrease in precipitation in the last 3 decades). …”

Correlating Global Gene Regulation to Angiogenesis in the Developing Chick Extra-Embryonic Vascular System by Sophie Javerzat (257199)

“…Seven percent of analyzed genes showed a significant change in expression (>2-fold, FDR<5%) with a peak occurring from E7 to E10, when key morphogenetic and angiogenic genes such as BMP4, SMO, HOXA3, EPAS1 and FGFR2 were upregulated, reflecting the state of an activated endothelium. …”