DataSheet1_Network analysis and experimental pharmacology study explore the protective effects of Isoliquiritigenin on 5-fluorouracil-Induced intestinal mucositis.PDF by Yi-fan Liao (13914312)

“…However, intestinal mucositis caused by 5-FU is a severe dose-limiting toxic effect and even leads to treatment interruption. …”

Image5_Modification of Fibronectin by Non-Enzymatic Glycation Impairs K+ Channel Function in Rat Cerebral Artery Smooth Muscle Cells.JPEG by Yan Yang (33204)

“…Bovine FN (1 mg/ml) was glycated (gFN) for 5 days using methylglyoxal (50 mM), and albumin was similarly glycated as a non-matrix protein control. …”

Image 5_Genomic, transcriptomic, and T cell receptor profiling in stratifying response to first-line chemoradiotherapy or radiotherapy for esophageal squamous cell carcinoma.jpeg by Xiaqin Zhang (10211396)

Table_5_Single-Cell Glia and Neuron Gene Expression in the Central Amygdala in Opioid Withdrawal Suggests Inflammation With Correlated Gut Dysbiosis.XLSX by Sean J. O’Sullivan (6910763)

Image_5_Single-Cell Glia and Neuron Gene Expression in the Central Amygdala in Opioid Withdrawal Suggests Inflammation With Correlated Gut Dysbiosis.TIF by Sean J. O’Sullivan (6910763)

Amounts of PRL and VEGF in conditioned medium of SDR-P-1D5 and MSH-P3 cultured cells under hypoxic conditions. by Naoto Tani (5459303)

“…<p>PRL levels under hypoxic conditions in (a) SDR-P-1D5 and (b) MSH-P3 cells. PRL were found to be at high levels in SDR-P-1D5 and MSH-P3 cells after 10 min incubation under 3% hypoxic conditions. …”

Leveraging Peripheral CB1 Antagonism in 1,4,5,6-Tetrahydropyridazine-Based Amidine Substituted Sulfonyl Analogs for Treating Metabolic Disorders by Pinaki Bhattacharjee (11971366)

“…Initial synthesis included compounds <b>10a</b>–<b>u</b>, followed by expansion into distinct amidine groups <b>(11a–18e</b>) for detailed structure–activity relationships. …”

Inactivation of <i>Six5</i>, <i>Dmpk</i> or <i>Mbnl1</i> does not affect Pavlovian contextual fear conditioning. by Anna Matynia (46702)

“…Baseline activity levels (arbitrary units) prior to the foot shock (panels iii) and activity bursts (velocity, cm/s, panels iv) are shown. A) <i>Six5^−/−</i> (white, n = 7) mutant mice display no differences in context fear conditioning freezing, activity suppression, activity level or activity burst phenotypes compared to the <i>Six5^+/+</i> wild type littermate controls (black, n = 6). …”

Leveraging Peripheral CB1 Antagonism in 1,4,5,6-Tetrahydropyridazine-Based Amidine Substituted Sulfonyl Analogs for Treating Metabolic Disorders by Pinaki Bhattacharjee (11971366)

“…Initial synthesis included compounds <b>10a</b>–<b>u</b>, followed by expansion into distinct amidine groups <b>(11a–18e</b>) for detailed structure–activity relationships. …”

Leveraging Peripheral CB1 Antagonism in 1,4,5,6-Tetrahydropyridazine-Based Amidine Substituted Sulfonyl Analogs for Treating Metabolic Disorders by Pinaki Bhattacharjee (11971366)

“…Initial synthesis included compounds <b>10a</b>–<b>u</b>, followed by expansion into distinct amidine groups <b>(11a–18e</b>) for detailed structure–activity relationships. …”

DataSheet_1_Critical Roles of Spätzle5 in Antimicrobial Peptide Production Against Escherichia coli in Tenebrio molitor Malpighian Tubules.docx by Maryam Ali Mohammadie Kojour (11843237)

“…Here, we indicated that TmSpz5 has a functional role in response to bacterial infections. …”

Image_5_Combination of single-nucleus and bulk RNA-seq reveals the molecular mechanism of thalamus haemorrhage-induced central poststroke pain.tif by Tianfeng Huang (13896228)

Leveraging Peripheral CB1 Antagonism in 1,4,5,6-Tetrahydropyridazine-Based Amidine Substituted Sulfonyl Analogs for Treating Metabolic Disorders by Pinaki Bhattacharjee (11971366)

“…Initial synthesis included compounds <b>10a</b>–<b>u</b>, followed by expansion into distinct amidine groups <b>(11a–18e</b>) for detailed structure–activity relationships. …”

Leveraging Peripheral CB1 Antagonism in 1,4,5,6-Tetrahydropyridazine-Based Amidine Substituted Sulfonyl Analogs for Treating Metabolic Disorders by Pinaki Bhattacharjee (11971366)

“…Initial synthesis included compounds <b>10a</b>–<b>u</b>, followed by expansion into distinct amidine groups <b>(11a–18e</b>) for detailed structure–activity relationships. …”

Data_Sheet_1_Asthmatic Bronchial Smooth Muscle Increases CCL5-Dependent Monocyte Migration in Response to Rhinovirus-Infected Epithelium.docx by Benoit Allard (522753)

“…However, we demonstrated that CCL5 was further increased in the asthmatic BSM co-culture and that anti-CCL5 blocking antibody significantly decreased monocyte migration induced by HRV-infected BE. …”

The 5′ Flanking Region and Intron1 of the Bovine Prion Protein Gene (<em>PRNP</em>) Are Responsible for Negative Feedback Regulation of the Prion Protein by Guangai Xue (179316)

“…The PrP-expressing plasmid pEF-boPrP and luciferase-expressing plasmids containing the partial promoter fragment of <em>PRNP</em> incorporating naturally occurring single-nucleotide or insertion/deletion polymorphisms were transfected into N2a cells. Transfection of pEF-boPrP induced PrP overexpression and decreased the promoter activity of <em>PRNP</em> in the wild-type haplotype (23-bp Del, 12-bp Del, and −47C). …”

Table_5_Maternal High-Protein and Low-Protein Diets Perturb Hypothalamus and Liver Transcriptome and Metabolic Homeostasis in Adult Mouse Offspring.XLSX by Lisa J. Martin (228675)

“…Perinatal HP/LC and LP/HC exposures resulted in a decreased ability to clear glucose in the offspring, with reduced baseline insulin and glucose concentrations in the LP/HC group and a reduced insulin response post-glucose challenge in the HP/LC group. …”

Image_5_Function and Mechanism of Trimetazidine in Myocardial Infarction-Induced Myocardial Energy Metabolism Disorder Through the SIRT1–AMPK Pathway.JPEG by Xiu-ying Luo (10984614)

“…The current study set out to evaluate the effect and mechanism of TMZ on MEM disorder induced by myocardial infarction (MI). Firstly, a MI mouse model was established by coronary artery ligation, which was then treated with different concentrations of TMZ (5, 10, and 20 mg kg^–1 day^–1). …”

Image_5_Underwater Acoustic Ecology Metrics in an Alaska Marine Protected Area Reveal Marine Mammal Communication Masking and Management Alternatives.PNG by Christine M. Gabriele (3297708)

“…RA was approximated from the quietest 5th percentile noise statistics based on a year (2011) of continuous audio data from a hydrophone in GBNP, in the frequency bands of whale and seal sounds of interest: humpback “whup” calls (50–700 Hz, 143 dB re 1 μPa source level, SL); humpback song (224–708 Hz, 175 dB SL), and harbor seal roars (4–500 Hz, 144 dB SL). …”

Supplementary Revised Figure S2 from MUC16 Regulates TSPYL5 for Lung Cancer Cell Growth and Chemoresistance by Suppressing p53 by Imayavaramban Lakshmanan (281140)