<i>Rfx4</i>^-/- embryos at E12.5 and E14.5 exhibit holoprosencephaly. by Ping Xu (122619)

“…<p>Note the complete absence of the developing cerebral hemispheres (CH) in the KO embryo seen in A-C. There was a striking decrease in size of all regions of the brain, but especially the developing midbrain in (D). …”

Values for the calculation of the time-dependent drug concentrations in the system based on observed data found and derived from a variety of sources. by J. Roadnight Sheehan (20141887)

Activity coupling between V2 and the CPu. by Anett J. Nagy (5447606)

“…<p>(A) Experimental schematics showing the simultaneous recording of the LFPs and SUA in both the V2 and the dorsomedial CPu. …”

Nutritional Control of DNA Replication Initiation through the Proteolysis and Regulated Translation of DnaA by David J. Leslie (764323)

“…Instead, we demonstrate that decreased nutrient availability downregulates <i>dnaA</i> translation by a mechanism involving the 5' untranslated leader region of the <i>dnaA</i> transcript; Lon-dependent proteolysis of DnaA then outpaces synthesis, leading to the elimination of DnaA and the arrest of DNA replication. …”

A Family of Octahedral Rhenium Cluster Complexes [Re₆Q₈(H₂O)<i>_n</i>(OH)₆_-<i>_n<... by Konstantin A. Brylev (1379436)

An old medicine as a new drug to prevent mitochondrial complex I from producing oxygen radicals by Dominique Detaille (3768979)

“…<div><p>Findings</p><p>Here, we demonstrate that OP2113 (5-(4-Methoxyphenyl)-3H-1,2-dithiole-3-thione, CAS 532-11-6), synthesized and used as a drug since 1696, does not act as an unspecific antioxidant molecule (i.e., as a radical scavenger) but unexpectedly decreases mitochondrial reactive oxygen species (ROS/H₂O₂) production by acting as a specific inhibitor of ROS production at the I_Q site of complex I of the mitochondrial respiratory chain. …”

Image_5_A new small molecule DHODH-inhibitor [KIO-100 (PP-001)] targeting activated T cells for intraocular treatment of uveitis — A phase I clinical trial.TIF by Stephan Thurau (10213218)

Decreased levels of soluble amyloid β-protein precursor and β-amyloid protein but increases of intrathecal axonal degradation products and TGF-β in patients with cerebral lupus by Estelle Trysberg (58614)

DataSheet_1_Citrus reticulatae pericarpium Extract Decreases the Susceptibility to HFD-Induced Glycolipid Metabolism Disorder in Mice Exposed to Azithromycin in Early Life.docx by Hanqi Lu (8563149)

“…</p>Methods and Results<p>Three-week-old mice were treated with AZT (50 mg/kg/day) via drinking water for two weeks and then were fed a CRP diet (1% CRP extract) for four weeks and an HFD for five weeks. …”

Selected images from the child-friendly reward task. by Melissa K. Peckins (12042132)

Table_1_Comparison of the First and Second Wave of Infections by SARS-CoV-2: A Retrospective and Longitudinal Study From a Primary Health Care Center in Santiago of Chile.docx by Claudio Acuña-Castillo (512379)

“…In addition, we observed that infections in the second wave were mainly in young patients with reduced comorbidities. The population with a complete vaccination schedule shows a decrease in the duration of symptoms related to the disease, and patients with more comorbidities tend to develop severe illness. …”

IQGAP1 is a protein that plays a critical role in regulating the level of apoptosis in endothelial cells. by Shaojun Huang (12489901)

“…<p>(A) The Annexin V–FITC/propidium iodide (PI) assay results indicate that Si-IQGAP1 can slightly decrease the apoptosis rate of normal cells, whereas knocking down IQGAP1 in PA-induced cells (PA + Si-IQGAP1) can significantly reduce the apoptosis rate. …”

<i>Arid1a</i>^<i>d/d</i> mice exhibited an altered decidualization. by Tae Hoon Kim (128536)

“…The uterine weight ratio was significantly decreased in <i>Arid1a</i>^<i>d/d</i> mice as compared to <i>Arid1a</i>^<i>f/f</i> (C) Histology of control and stimulated horn in <i>Arid1a</i>^<i>f/f</i> (a and c) and <i>Arid1a</i>^<i>d/d</i> mice (b and d) at day 5, respectively (D) The expression of decidualization marker genes, <i>Bmp2</i>, <i>Fst</i> and <i>Fkbp5</i> was measured in the uteri of control and stimulated horn. …”

Cardiac percentage engraftment 24h post-injection. by Kristine Yee (668076)

LANA NBs functions as transcription memory. by Tomoki Inagaki (12903779)

HTS assay development. by Marion E. Joy (521335)

Data Sheet 1_A cost-reducing reimbursement programme? Effects of value-based reimbursement on healthcare costs.docx by Thérèse Eriksson (20413838)

The hybrid incompatibility proteins HMR and LHR interact in a defined HMR/LHR complex. by Andrea Lukacs (3752956)

Investigating the incorporation of milled rice in brewing non-alcoholic beer to enhance sensory quality by Christian Schubert (330503)

“…Original gravities ranged from 6.71% w/w (100% barley malt) to 7.15% w/w (100% rice), with alcohol contents between 0.33% v/v (70% barley/30 %rice) and 0.45 % v/v (100% rice). …”

Metastasis rate of SCLC cells is reduced in E-/P- selectin knockout mice. by Franziska Heidemann (546600)

“…In a parallel approach OH-1 cells were subcutaneously injected in select (n = 5) or wt (n = 3) mice and tumors grown for 36–65 days. …”