Cardamonin inhibited tumor growth and decreased FASN and Raptor. by Peiguang Niu (17044532)

“…Cardamonin reduces the protein expression of Raptor, thereby inhibiting the mTORC1-regulated DNL pathway. This leads to a decrease in free fatty acid levels. Subsequently, the reduced levels of free fatty acids inhibit the activity of mitochondrial CPT-1 and induces mitochondrial dependent apoptosis. …”

The LCS stream is absent in E16.5 <i>Emx1</i>-cKO mice. by Sathish Venkataramanappa (10331993)

Fig 5 - by Qingxi Shen (3547970)

A genetic variant in human FIRE is associated with a decreased interferon response in myeloid cells. by Anaïs Assouvie (9600529)

19606 decreases the luminal pH of the ACV during infection. by Jesus S. Distel (11250759)

Combination of cAMP-enhancing and cAMP-inhibiting neuromodulation can increase or decrease the AP threshold throughout the apical dendrite in the Hay-model L5PC. by Tuomo Mäki-Marttunen (388882)

Increasing TPP side chain length decreases melanoma cell viability and clonogenic survival. by Kyle C. Kloepping (9928265)

“…A375 melanoma cells were treated with 0.25 μM, 0.5 μM, or 1.0 μM 5-, 8-, 10-, 12-,14-, or 16-TPP for (C) 24 h and (D) 48 h and analyzed for clonogenic survival (* represents when 12-, 14-, and 16-TPP were significant relative to 5-TPP and 8-TPP; Ψ represents when 10-TPP was significant relative to 5-TPP and 8-TPP; p < 0.05; n = 3 from 2 separate experiments; N = 6). …”

Image_5_C5a/C5aR1 Pathway Is Critical for the Pathogenesis of Psoriasis.JPEG by Quan-you Zheng (713217)

“…Moreover, C5aR1 deficiency significantly decreased IMQ-induced infiltration of plasmacytoid dendritic cells (pDCs), monocytes and neutrophils in psoriatic skin lesions and functions of pDCs, evidenced by the remarkable reduction in the IMQ-induced production of interferon-α (IFN-α) and tumor necrosis factor α (TNF-α), and FMS-like tyrosine kinase 3 ligand (FLT3L)-dependent pDCs differentiation. …”

I348T increases H77 entry dependency on SR-BI, while T385P decreases H77 entry dependency on SR-BI. by Christina Holmboe Olesen (11154333)

HSP90 inhibition by RGRN-305 decreased the gene expression of proinflammatory cytokines induced by SARS-CoV-2 S protein. by Hakim Ben Abdallah (14578241)

Changes of peritoneal structure and function in rats. by Yangyang Yin (14323701)

Subjects:

The effect of MiR-132-3p on protein expression in TGF-<i>β</i>1/Smad2/3 signaling pathway was observed by immunofluorescence. by Yangyang Yin (14323701)

Subjects:

BA decreases mitochondrial membrane potential and superoxide production after one day of cell culture. by Bandik Föh (602419)

“…<p>(A) Representative contour plots of MT-Green/TMRE-stained B cells after incubation with 0.5 mM BA for 1 day. …”

pDNA-PK levels are decreased in absence of cGAS. by Elona Gusho (4688170)

Absence of FumC leads to decreased susceptibility to bactericidal antibiotics. by Stephanie D. Himpsl (8501868)

Juvenile demyelination leads to a decrease in axonal complexity of PFC PV interneurons. by Sara Hijazi (21656615)

“…</b> Quantification of the overall myelin intensity in PFC of both groups shows a clear loss of myelin in the juvenile demyelination group (<i>t test; n = 6/5 mice per group, ***p < 0.001</i>). …”

Excision of HIF1α decreases viral reactivation from latency in infected splenocytes in vivo. by Darlah M. López-Rodríguez (8098544)

JBPOS0101 decreased Amyloid Beta (Aβ) aggregates in the cortex and hippocampal regions in 5xFAD mouse brains. by Jihoon Jeong (4852690)

Silencing <i>cullin-1/5</i> decreased mRNA and protein expression of NF-κB dependent cytokines. by Attinder Chadha (11414273)

Subjects:

Fig 5 - by Shiqi Luo (3829597)