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DataSheet_1_PACAP–PAC1 Signaling Regulates Serotonin 2A Receptor Internalization.pdf
Published 2021“…In addition, the levels of endogenous 5-HT<sub>2A</sub> were decreased on the cell surface of primary cultured cortical neurons after PACAP stimulation and were increased in frontal cortex cell membranes of Pacap<sup>−/−</sup> mice. …”
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Video_5_Contribution of 5-HT2 Receptors to the Control of the Spinal Locomotor System in Intact Rats.WMV
Published 2020“…Little is known about the role of 5-HT receptors in the control of voluntary locomotion, so we administered inverse agonists of 5-HT<sub>2</sub> (Cyproheptadine; Cypr), 5-HT<sub>2A</sub> neutral antagonist (Volinanserin; Volin), 5-HT<sub>2C</sub> neutral antagonist (SB 242084), and 5-HT<sub>2B/2C</sub> inverse agonist (SB 206553) receptors intrathecally in intact rats and monitored their effects on unrestrained locomotion. …”
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Table_1_Trait sensitivity to negative feedback in rats is associated with increased expression of serotonin 5-HT2A receptors in the ventral hippocampus.DOCX
Published 2023“…The results demonstrated that trait sensitivity to negative feedback is associated with increased mRNA expression of the 5-HT2A receptors in the rat ventral hippocampus (vHipp). …”
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GSK343 treatment decreased <i>in vivo</i> tumor volume and growth.
Published 2021“…(A) Animals treated with GSK343 had significantly decreased fold change in tumor volumes compared to mice treated with vehicle. …”
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TUDCA decreases ER stress in HOX neonatal rat lungs.
Published 2022“…<p>(<b>A</b>) The expression levels of ER stress markers (P-PERK 0.6±0.1-fold, p<0.001, n = 5; PERK 0.7±0.1-fold, p = 0.00364, n = 5; P-IRE1α 0.6±0.0-fold, p<0.001, n = 5; IRE1α 0.6±0.1-fold, p<0.001, n = 5; GRP78 0.8±0.1-fold, p<0.001, n = 5; cleaved ATF6 0.1±0.0-fold, p<0.001, n = 5; spliced XBP1 0.3±0.0-fold, p<0.001, n = 5; 2 males and 3 females) are all decreased while the N-glycosylated VEGFR2 is increased (3.5±0.2-fold, p<0.001, n = 5) in HOX neonatal lungs at P10 indicating TUDCA can attenuate hyperoxia-induced ER stress. …”
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Presentation_1_Constitutive Serotonin Tone Modulates Molecular and Behavioral Response to Chronic Fluoxetine Treatment: A Study on Genetic Rat Model.pdf
Published 2021“…Platelet 5HT levels, a recognized indicator of SSRI efficacy, were decreased by fluoxetine treatment in both 5HT-sublines. …”