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Table_1_Sub-Acute Treatment of Curcumin Derivative J147 Ameliorates Depression-Like Behavior Through 5-HT1A-Mediated cAMP Signaling.DOCX
Published 2020“…Background<p>Major depressive disorder (MDD) is a severe mental disorder related to the deficiency of monoamine neurotransmitters, particularly to abnormalities of 5-HT (5-hydroxytryptamine, serotonin) and its receptors. …”
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WT1 siRNA decreases proliferation, pAKT, and Bcl2 expression.
Published 2024“…Corresponding densitometry analysis is noted as protein fold expression compared to GAPDH for WT1, p<0.001(***), vFLIP(ns), LANA p<0.05(*), pAKT p<0.05(*), and BCL2 p <0.05(*) using two-sided, unpaired student t-tests. …”
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5.HT<sub>1A</sub> binding difference between known cause of death (KCOD) controls and SIDS.
Published 2025“…When SIDS is compared to all KCOD controls, the HG, NTS, and MAO show a significant mean difference in 5-HT<sub>1A</sub> receptor binding. …”
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Data_Sheet_1_Determining 5HT7R’s Involvement in Modifying the Antihyperalgesic Effects of Electroacupuncture on Rats With Recurrent Migraine.pdf
Published 2021“…<p>Electroacupuncture (EA) is widely used in clinical practice to relieve migraine pain. 5-HT<sub>7</sub> receptor (5-HT<sub>7</sub>R) has been reported to play an excitatory role in neuronal systems and regulate hyperalgesic pain and neurogenic inflammation. 5-HT<sub>7</sub>R could influence phosphorylation of protein kinase A (PKA)- or extracellular signal-regulated kinase<sub>1</sub><sub>/</sub><sub>2</sub> (ERK<sub>1</sub><sub>/</sub><sub>2</sub>)-mediated signaling pathways, which mediate sensitization of nociceptive neurons via interacting with cyclic adenosine monophosphate (cAMP). …”
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