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    <i>MTHFR</i>677C → T genotype modulates the effect of a 5-year supplementation with B-vitamins on homocysteine concentration: The SU.FOL.OM3 randomized controlled trial by Leopold K. Fezeu (5309333)

    Published 2018
    “…</p><p>Methods</p><p>2381 patients with a personal history of cardiovascular disease were randomly assigned to one of four groups: 1) B-vitamins alone (560 μg of 5-methyl-THF, 3 mg of vitamin B<sub>6</sub> and 20 μg of vitamin B<sub>12</sub>), 2) n-3 fatty acids alone (600 mg of EPA and DHA in a 2:1 ratio), 3) B-vitamins and n-3 fatty acids, and 4) placebo. …”
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