DataSheet1_Network pharmacology and experimental analysis to reveal the mechanism of Dan-Shen-Yin against endothelial to mesenchymal transition in atherosclerosis.ZIP by Mengyun Hong (13301475)

“…Experimentally, DSY could efficiently modify expression of signature EndMT genes and decrease expression of PI3K/AKT pathway signals including integrin αV, integrin β1, PI3K, and AKT1 in TGF-β2-treated HUVECs. …”

XAV939 blocks Wnt/β-catenin signalling in breast cancer cells. by Renyue Bao (121721)

“…Cells were treated overnight with 5 µM 21H7 and 1 or 5 µM XAV939 in the presence of control or Wnt3a conditioned medium with 5%, 1.25% or 0.2% FBS. …”

Psychophysical performance of Exposed (square data points) and Unexposed (round data points) groups. by Thomas J. Brozoski (421479)

“…<b>B</b>. After 72 hrs of D-AP5 infusion the treated Exposed group significantly diverged from the untreated Exposed group (statistics summarized in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0077674#pone-0077674-t001" target="_blank">Table 1</a>, section 2), indicating decreased tinnitus. …”

Hibernation temperature-dependent <i>Pseudogymnoascus destructans</i> infection intensity in Palearctic bats by Natália Martínková (238012)

“…Contrary to expectation derived from laboratory <i>P. destructans</i> culture experiments, natural infection intensity peaked between 5 and 6°C and decreased at warmer hibernating temperature. …”

Supplementary Material for: Association between self-reported oral health and Parkinson's disease: evidence from UK biobank by Yi X. (10991379)

“…Results We included 421180 participants with a mean age of 56.26 years old and 46.5% of them were male. …”

Physiological risk of falls, physical and aerobic capacity in community-dwelling elderly by Lygia Paccini Lustosa (4650658)

“…Results: Participated 59 elderly (71.8±5.0 ys). The mean performance in PPA was 0.4±0.4; SPPB was 10.4±1.7 and ISWT was 281±111.7 meters. …”

Effect of Nic on BDNF synthesis and release in HBO cells and HEK293 cells. by Jie Qian (565984)

“…Relative to control BDNF concentration in cell lysate increased at 0.25 μM Nic (p = 0.0274) and decreased at 0.5 μM Nic (p = 0.0055). No significant increase in BDNF concentration was observed at 0.25 μM Nic, however, at 0.5 μM Nic, BDNF concentration was significantly increased relative to control (p = 0.0001). …”

Lung phenotype of <i>UPK II-Cre;LSL-K-ras^G12D</i> mice. by Francisco Ayala de la Peña (554607)

“…<b>I–J</b>: Morphometric analysis of lung sections showed a decreased total air space (<b>I</b>) and mean alveolar (saccular) area (<b>J</b>) in <i>UPK II-Cre;LSL-K-ras^G12D</i> mice at E17.5 (n = 5); the impairment of air space development led to an increased total air space area and mean alvelolar area in the early postnatal period (P1; n = 12) in transgenic mice when compared to controls; bars, SEM. …”

Table_1_Favorable Effects of Tacrolimus Monotherapy on Myasthenia Gravis Patients.DOCX by Zhirong Fan (9566711)

“…QMG scores significantly decreased at 6 and 12 months, with mean differences and 95% CIs of −4.67(−6.88, −2.45) and −5.77 (−7.55, −4.00), respectively. …”

Data_Sheet_1_Operant Assessment of DMTP Spatial Working Memory in Mice.docx by Jasper Teutsch (7311953)

“…Its frequent and pharmacoresistent impairment in mental health disorders urges the development of rodent paradigms through back-translation of human WM tests, ideally avoiding the confounds of alternation-based assays. Here we show, that mice can acquire a delayed-matching-to-position (DMTP) operant spatial WM (SWM) paradigm that is akin to the combined attention and memory (CAM) task previously developed for rats, and that relies on a 5-choice wall [5-CSWM, 5-choice based operant testing of SWM (5-CSWM)]. …”

MMP-9 and MMP-8 levels in protracted ARDS. by Michele Y. F. Kong (346852)

“…B: Decline in MMP-8 levels with ARDS progression. Total MMP-8 decreased with ARDS progression in those who remained intubated for >5 days (n = 25, mean±SEM 1245±343 ng/mg at 48 hrs vs. 537±122 ng/mg at day 6, respectively; *<i>p<0.05</i>).…”

C1 shows similar results on macrophages as for microglia and does not interfere with cell activity, proliferation, and cell death are not affected in non-stimulated conditions. by Philipp Jordan (9364068)

“…The LPS induced release of IL1β and IL6 was not changed in the presence of C1 or DMSO. DMSO showed a significant effect on the release of TNFα in the concentrations 1.25x10^-5 v/v (p < 0.0001) and 12.5x10^-5 v/v (p = 0.005). 2.5 μM C1 decreased the release of TNFα significantly to 91% compared to the positive control (p = 0.0313). *** p<0.001 ** p<0.01 * p<0.05 comparing to stimulated control, ### p<0.001 ## p<0.01 ## p<0.05 comparing to DMSO (1way ANOVA followed by Bonferroni’s post-hoc test).…”

Data_Sheet_1_Real-Time Multifrequency MR Elastography of the Human Brain Reveals Rapid Changes in Viscoelasticity in Response to the Valsalva Maneuver.docx by Helge Herthum (10748307)

“…We observed that | G^∗| increased while φ decreased due to VM and, less markedly, due to breath-hold in inspiration. …”

Effects of ligand stimulation and targeted therapeutics on IGF1R and IR expression and phosphorylation. by Jurriaan Brouwer-Visser (578686)

“…Measured by RT-qPCR (n = 5 independent experiments each done in triplicate) IR-A and IR-B mRNA levels in HEY-T30 are significantly decreased when compared to HEY, while similar levels are observed when comparing A2780-T15 to A2780. …”

The vertical distributions of soil microbial biomass and soil organic carbon across terrestrial ecosystems by Yun Liang (10357601)

Supplemental figures by Jenny Sones (20102439)

“…<a href="" target="_blank">BPH/5 pregnant colons had decreased expression of free fatty acid receptor, <i>GPR41</i>. …”

Modulations in activity dynamics in pyramidal (Pyr) neuron (black lines) and parvalbumin (PV) interneuron (red lines) populations by disrupting the excitatory/inhibitory (E/I) bala... by Nobuhiko Wagatsuma (494052)

“…</i></b> Typical pattern of the time course of neuronal activity in Pyr and PV populations with an E/I ratio of 4.5:1.0 caused by a decrease in PV interneuron number. …”

Gene expression changes in MEF cells. by Satoshi Miuma (117853)

Behavioral data. by Charmaine Y. Pietersen (37545)

Articulo 017 FASEB Journal.pdf by Juan Antonio Gimenez-Bastida (6442297)

“…HKs result from the rearrangement of a di-endoperoxide intermediate formed in the COX-2-dependent oxygenation of 5<i>S</i>-hydroxyeicosatetraenoic acid (5<i>S</i>-HETE). …”