Data_Sheet_1_The Isolate Caproiciproducens sp. 7D4C2 Produces n-Caproate at Mildly Acidic Conditions From Hexoses: Genome and rBOX Comparison With Related Strains and Chain-Elongat... by Sofia Esquivel-Elizondo (4438618)

“…However, this was considerably higher at 83.1 ± 0.44% when both fructose and n-butyrate (electron acceptor) were combined as a substrate. A comparison of 7D4C2 cultures with fructose and n-butyrate with an increasing pH value from 4.5 to 9.0 showed a decreasing n-caproate specificity from ∼92% at mildly acidic pH (pH 4.5-5.0) to ∼24% at alkaline pH (pH 9.0). …”

Cholinergic Modulation of Narcoleptic Attacks in Double Orexin Receptor Knockout Mice by Mike Kalogiannis (224818)

“…The muscarinic antagonist atropine (0.5 mg/kg, IP) decreased the number of arrests, also without altering arrest lifetimes. …”

Ndrg2 mRNA is induced in wt mice by FXR agonists, reduced in livers of FXR^−/− versus wt mice and both FXR and NDRG2 mRNAs are reduced in human HCC versus normal liver.... by Ulrich Deuschle (129085)

“…Relative mRNA levels of Ndrg2, Shp, Cyp7a1 and Cyclophilin E were determined by RT-qPCR from wt (n = 5) and FXR^−/− (n = 5) mice as indicated. …”

<i>In vitro</i> validation of VH411 phage binding. by Marion David (366485)

“…In the present example, the cells were incubated with the anti-PVIII antibody (1/1000) detected with an allophycocyanine (APC) secondary antibody (1/800) (vertical axis) (B1, B3, B4, B5, B6) and with the anti-LDLR antibody (1/50) detected with a secondary FITC-labeled antibody (1/800) (horizontal axis) (B2, B3, B4, B5, B6). …”

DataSheet_1_Circulating microRNA responses to acute whole-body vibration and resistance exercise in postmenopausal women.docx by Samuel R. Buchanan (12253793)

“…There was a significant modality × time interaction for c-miR-21-5p expression (p=0.019), which decreased from 60P to 24H after WBV only. …”

Data_Sheet_1_miR-212 and miR-132 Are Downregulated in Neurally Derived Plasma Exosomes of Alzheimer’s Patients.PDF by Diana J. Cha (8041226)

“…ROC analysis indicated that measurement of miR-132-3p in neurally-derived plasma EVs showed good sensitivity and specificity to diagnose AD, but did not effectively separate individuals with AD-MCI from controls. Moreover, when we measured the levels of a related miRNA, miR-212, we found that this miRNA was also decreased in neural EVs from AD patients compared to controls. …”

Metabolites displaying the highest differences between TCF7L2 risk genotype carriers and controls. by Cornelia Then (81529)

“…Delta t35 (p = 2.7E-03) and t240 (p = 4.2E-03) of PC ae C40:5 are given as a representative example. Data are given as mean and standard error of the mean. * = p ≤ 0.05 after correction for multiple testing.…”

Effect of population size on the magnitude of distortion. by Alexander Coulton (8468724)

“…The dashed lines mark the 5% significance threshold for a chi-square test, whilst the dotted line marks a 1:1 segregation ratio. …”

MPA gap analysis results based upon alternate choices of datasets. by Casey C. O'Hara (3997529)

“…Scenario 2 updates the results using AquaMaps version 08/2015, showing very small changes despite the inclusion of an additional 5,545 species. Scenario 3, still using 2015 AquaMaps data, drops the presence threshold to zero, showing an expected decrease in gap species, but also a decrease in species with 5% or greater protected range. …”

Example simulation of the 2D Ising model. by Manfred Füllsack (4691716)

“…<p>Simulation of the 2D-Ising model with an external magnetic field H taken as critical parameter (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0259177#pone.0259177.e001" target="_blank">Eq 1</a>), on the x-axis, first increasing (H = -0.5 to 0.6, left half) and then decreasing (H = 0.6 to -0.5, right half). …”

Pace Versus Prediction: Is the Experience of the Runner Associated With Marathon Success? by Dan Gordon (2110918)

“…Significant differences observed between PT and FT for all EXP groups apart from EXP-5 (P= 0.0001). EXP-0 showed significant difference across all split times apart from 35-40 km (P=0.0001) with a decrease in normalised speed from 5km (109.0 ±7.6) –40km (89.9 ±7.4%). …”

12-HETE induces phosphorylation of VEGF-R2 and dephosphorylation of protein tyrosine phosphatase (PTP) SHP1 in REC. by Amira Othman (380131)

“…<p>Western blotting analysis (A) demonstrated significant increase in the level of pVEGF-R2 after 5 and 60 minutes from the beginning of treatment with 12-HETE. …”

Stronger evidentiary standards do not reduce the need to publish negative outcomes by Silas Boye Nissen (6815351)

“…Figure 6 Strengthening evidentiary requirements does not necessarily decrease canonization of false facts. In panel A, the false positive rate is α=0.05, the false negative rate is β=0.2, the original belief in the claim is q_0=0.5, and the evidentiary standards are symmetric τ_1=1-τ_0. …”

Halo assay performed in MCF7 cells. by Siddharth Manvati (391250)

“…<p>(a) NDF-nuclear diffusion factor-values showing the extent of DNA damage with increasing concentrations of etoposide (p Value <0.001), (b) Percentage of senescent cell population (using β-gal assay) and Annexin-V positive-apoptotic-cell population (through FACS analysis): showing decrease in senescence and increase in Apoptosis (*p Value <0.05), (c) miR-101 expression (using Real-Time PCR): showing decrease with increasing concentration of etoposide (1 µM, 5 µM and 10 µM) for 12 hrs (**p Value <0.005).…”

ID2 expression is inversely correlated to miR-9 and miR-103. by Daniela Annibali (148125)

“…<p>Ectopic expression of miR-9 and miR-103 decreases ID2. (<b>A</b>) Immunoblotting of ID2 in SK-N-BE (upper panel) and SH-SY5Y (lower panel) cells treated with RA for 3, 6 and 10 days. …”

Chronic CSE treatment induced HIF1α accumulation via enhanced lactate production. by Wenyue Sun (134001)

“…<p>A. HIF1α levels in OKF6 cells were determined after 4 h of culture in glucose-free Krebs buffer containing 3 or 5 mmol/L lactate. …”

OLE reduces plaque burden in the cortex and hippocampus of TgCRND8 mice. by Cristina Grossi (358570)

“…Both Aβ40 and Aβ42 levels were significantly decreased in OLE-fed Tg versus age-matched untreated Tg (n<i> = </i>5/group) mice. …”

Data Sheet 1_Valve-in-valve transcatheter aortic valve replacement (TAVR) leads to lower device success compared to TAVR in native stenosis.pdf by Michael Paukovitsch (16428786)

“…While ViV-TAVR decreased peak and mean gradients significantly, in 31% of patients elevated mean gradients (≥20 mmHg) were observed at discharge. …”

Effects of omega-6/3 and omega-9/6 nutraceuticals on pain and fertility in peritoneal endometriosis in rats by Francisco Edson Ximenes Gomes Pereira (6675698)

“…Fertility was evaluated by counting the number of embryos in the left hemi-uterus. Results: The mean number of writhings was as follows: sham-operated, 11.1 ± 2.9; control with endometriosis, 49.3 ± 4.4; omega-6/3, 31.5 ± 2.7; omega-9/6, 34.1 ± 4.5; medroxyprogesterone acetate, 2.1 ± 0.8; meloxicam, 1 ± 0.3. …”

Figure CSA-2 4.15 by CIMR project (7352015)