Anacardic acid inhibits the binding of HATs to the <i>Gata4</i> promoter. by Chang Peng (611040)

“…<p>Alcohol could improve binding of P300, PCAF, SRC1 and CBP to the <i>Gata4</i> promoter on E14.5, and anacardic acid could repress binding of P300 and PCAF to the <i>Gata4</i> promoter in cardiac tissues whereas anacardic acid could not decrease binding of SRC1 and CBP to the <i>Gata4</i> promoter in the same cardiac tissues (A,B,C,D). *: P<0.01 vs. control group (n = 3), ^##: P<0.05 vs. alcohol group (n = 3). **: P<0.01 vs. alcohol group (n = 3).…”

mRNA levels in Brockmann bodies of rainbow trout incubated <i>in vitro</i> for 1 h at 15°C in modified Hanks’ medium containing 2 mM D-glucose alone (control) or containing 1, 10,... by Marta Librán-Pérez (393255)

Average calculation cost of next best pathway predictions. by Marco Reidelbach (6077978)

“…Perturbations: charge in-/decrease (left column), charge translocation (right column). …”

Long-term effects of 7-year warming experiment in the field on leaf hydraulic and economic traits of subtropical tree species by Wu Ting (9355046)

“…<i>M. breviflora </i>(300 m), <i>S. rehderianum</i>,<i> S. superba</i> and <i>I. chinensis </i>(300 m and 30 m) exhibited higher area-based and mass-based maximum photosynthetic rates (A_a and A_m, respectively) related to increasing stomatal conductance (g_s) and stomatal density in the wet season, which led to rapid growth; however, we observed decreased growth of <i>M. breviflora </i>at 30 m due to lower stomatal density and decreased A_a in the wet season. …”

LncRNAs differentially expressed in PD leukocytes. by Lilach Soreq (89966)

“…Of these, 8 exhibited disease-mediated decrease, and 5- increase. For each lncRNA, given are is ensEMBL transcript ID, log fold change in PD (pre-DBS) compared to HC, FDR and chromosomal location, as well as the average count read, and count per million (CPM) in the leukocyte sequenced libraries. …”

Co-immunoprecipitation of CFTR, HSPs, VCP, and HDAC6 in the N1303K and S1235R cell lines treated or untreated with the compounds. by Daniele Rapino (506785)

“…<p>HEK 293 cell lines stably expressing either mutant were treated with C3+C4 (5μM), and CFTR was immunoprecipitated with anti-CFTR antibody M3A7. …”

Profiling the RNA levels of cancer-related genes in the analysed FMCs. by Daniela Ferreira (173362)

“…Each quantification graphic also presents the percentage of tumours with increase (≥2-folds), maintenance (between 0.5 and 2-folds) or decrease (≤0.5-folds) RNA levels of each gene. …”

Effects of L-DOPA on the expression of DMT1−IRE, DMT1+IRE, Fpn1 and TfR1 proteins in cortical neurons. by Fang Du (232423)

“…L-DOPA treatment induced a dose-dependent decrease in TfR. There were no significant differences in the levels of DMT1+IRE and Fpn1 protein between neurons treated with and without L-DOPA. * P<0.05, ** P<0.01 vs. the control.…”

PSI score versus effect of IE2F depletion on TSR strength. by Ming Li (91180)

“…<p>Each TSR is indicated by a small black dot. Repressed and activated TSRs increase and decrease in strength, respectively, when IE2F is depleted. …”

Treatment with dexamethasone prior to secondary live virus infection prevents airway hyperreactivity only in sensitized animals. by Christopher Skappak (417305)

“…<p>Some animals were treated with dexamethasone (i.p.) before the second live PIV infection. <b>(A)</b> Dexamethasone treatment of non-sensitized animals before secondary infection with PIV (n = 6) had no effect on bronchoconstriction in response to histamine (i.v.), compared to untreated animals (n = 5). …”

Changes in ambient noise spectrum during moonlight hours. by Daniel Duane (18189603)

“…<p>Changes in the spectrum of ambient noise during moonlight hours are shown in June 2020, a month where significant changes in biological noise are observed in all three frequency bands studied. …”

Modulation by decitabine of gene expression and growth of osteosarcoma U2OS cells and in xenografts: Identification of apoptotic genes as targets for demethylation-4 by Khaldoun Al-Romaih (79731)

“…There was a significant decrease (p < 0.001) in methylation quantity for each CpG position after decitabine treatment both and for the four genes in all sample but not in the NHOst (normal human osteoblasts). p-values were calculated by comparing the percentage of methylation for each individual CpG position in control cells with the same CpG position in the treated cells using student t-test and they all resulted in p < 0.001.…”

Figure 1 from Histone Deacetylase Inhibitors Target DNA Replication Regulators and Replication Stress in Ewing Sarcoma Cells by Stacia L. Koppenhafer (16616290)

“…<p>HDAC inhibitors decrease RRM1, RRM2, CHK1, and WEE1 protein levels. …”

Notch and Wnt signaling-mediated activation of Müller cells in S334ter rats <i>in vivo</i>. by Carolina Beltrame Del Debbio (243080)

“…Q-PCR analysis of gene expression revealed increase in levels of transcripts corresponding to <i>Ki67</i>, <i>cyclinD1</i>, <i>Hes1</i>, <i>Hes5</i> and decrease in <i>p27^kip1</i> transcript levels in Jag1+Wnt2b treated retina, compared to controls (<b>H</b>). …”

Gene expression analysis of <i>Pten</i> mutant prostates. by Isabel B. Lokody (755298)

“…<p>(A) i) Heatmap demonstrating that control samples (C1-C5) show similar expression patterns to each other, as do mutant samples (M1-M5). ii) Genes chosen for validation are indicated in heatmap derived from the average of control and mutant samples. …”

Summary of phenotypic data of the candidate genes implicated in HR-DSBR. by Mikołaj Słabicki (246635)

“…Genes that after knockdown decreased the frequency of HR below z-score −4, −2, or −1.5 are marked with ↓↓↓, ↓↓ or ↓, respectively; genes that increase the frequency of HR over z-score 4, 2, or 1.5 are marked with ↑↑↑, ↑↑, or ↑, respectively; n.a., not available. …”

Waterfall plot showing the quantitative changes in ER, PR, and Ki-67 expression. by Yuqin Ding (623253)

“…(A) ER discordance rate: 10.4% (50/482) of patients, including 36 (7.5%) patients with positive-to-negative conversion and 14 (2.9%) patients with negative-to-positive conversion; (B) PR discordance rate: 17.0% (82/482) of patients, including 57 (11.8%) patients with positive-to-negative conversion and 25 (5.2%) patients with negative-to-positive conversion; (C) Ki-67 discordance rates: 50.4% (243/448) of patients had decreased expression and 27.0% (130/448) of patients had increased expression.…”

Summary of case incidence (Exposed and Infected dog cases) per 10,000 dogs across 1000 simulations assuming increasing incursion probability and vaccination coverage values. by Kristyna Rysava (3213036)

“…<p>Summaries organized as in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1011187#pcbi.1011187.g005" target="_blank">Fig 5</a>. …”

Phosphorylation of PKA targets is greatest when PKA is colocalized with cAMP production either in the spine or in the dendrite. by Myungsook Kim (2166613)

“…(A2) Bar graph shows mean and s.e.m. of phospho-inhibitor-1 (n = 5 for each condition). …”

IL-1β depletion and IL-1 receptor antagonist treatment alleviated the neutrophilic inflammation. by Wen-Cheng Chao (2817868)

“…<p>The characteristic pulmonary histopathological images (A) of <i>M</i>. <i>marinum</i>-infected <i>Ncf1</i>^<i>-/-</i> mice and WT mice on day-5 with and without IL-1β depletion by a monoclonal antibody directed against IL-1β (150μg on day-1). …”