Silibinin improves palmitate-induced insulin resistance in C2C12 myotubes by attenuating IRS-1/PI3K/Akt pathway inhibition by H.B. Li (6514220)

Titration and characteristics of pressure-support ventilation use in Argentina: an online cross-sectional survey study by Joaquin Pérez (10437650)

Graphene oxide nanoparticles induce hepatic dysfunction through the regulation of innate immune signaling in zebrafish (<i>Danio rerio</i>) by Guanghua Xiong (8543577)

Effects of Dietary Supplementation of Soy Isoflavones on the Performance and Egg Quality in Native Chinese Breeder Hens by E Abdelghani (8183238)

Androgen receptor gene deficiency results in the reduction of steroidogenic potential in porcine luteal cells by Jaya Bharati (12843349)

Data Sheet 1_Treatment with pemafibrate ameliorates fatty liver index and atherogenic lipid profiles in Japanese patients with type 2 diabetes mellitus.pdf by Toru Suzuki (512729)

“…There was no significant change in hemoglobin A1c level over time. FLI (mean ± standard deviation: 68.1 ± 21.9 vs. 39.6 ± 25.0, P < 0.001), but not FIB-4 index as a marker of hepatic fibrosis (median [interquartile range]: 1.04 [0.78-1.39] vs. 1.01 [0.68-1.36], P = 0.909), was significantly decreased by treatment with pemafibrate for 12M, and the proportion of patients with metabolic dysfunction-associated SLD (MASLD) was significantly decreased from 92.3% (baseline) to 61.5% (12M).…”

Depiction of the number of <i>hrgs</i> found on each chromosome relative to the number of megabases in that chromosome. by Scott Severance (244896)

“…Light blue and dark blue bars represent a decrease in gene expression at 4 and 500 µM heme, respectively.…”

Accession numbers, mapping statistics, and matched RNA accession numbers for 99 Korean CRC whole-genome samples by Jae-Yoon Kim (22817186)

“…To provide insights into this, we present a high-quality multi-omics dataset consisting of whole genome sequencing (WGS) and RNA sequencing (RNA-seq) data from 49 EOCRC and 50 LOCRC patients. …”

Data_Sheet_1_One Century of Forest Monitoring Data in Switzerland Reveals Species- and Site-Specific Trends of Climate-Induced Tree Mortality.docx by Sophia Etzold (6496022)

“…However, tree mortality at the ecosystem level remains challenging to quantify since long-term, tree-individual, reliable observations are scarce. Here, we present a unique data set of monitoring records from 276 permanent plots located in 95 forest stands across Switzerland, which include five major European tree species (Norway spruce, Scots pine, silver fir, European beech, and sessile and common oak) and cover a time span of over one century (1898–2013), with inventory periods of 5–10 years. …”

Theoretical and Experimental Study of 3‑Pentanol Autoignition: Ab Initio Calculation, Shock Tube Experiments, and Kinetic Modeling by Yuan Feng (213823)

“…Furthermore, using an ST, ignition delay times (IDTs) for the 3-pentanol/air mixtures were measured spanning a temperature range of 920–1450 K, pressures of 6, 10, and 20 bar, and equivalence ratios of 0.5, 1.0, and 1.5. …”

Data_Sheet_1_Investigating the Binding Heterogeneity of Trace Metal Cations With SiO2 Nanoparticles Using Full Wave Analysis of Stripping Chronopotentiometry at Scanned Deposition... by Elise Rotureau (1611436)

“…Nonetheless, this might change for nanoparticulate systems as observed in a previous study of Pb(II) with a very small SiO₂ particle (7.5 nm diameter). …”

Serology for Trachoma Surveillance after Cessation of Mass Drug Administration by Diana L. Martin (300642)

“…Among 1–9 year olds, TF prevalence was 6.5%, whereas only 3.5% were seropositive. Force of infection modelling indicated a 10-fold decrease in seroconversion rate at a time corresponding to MDA commencement. …”

Scheme detailing the experiment design using Apoatã, Icatu, and Obatã plants. by José C. Ramalho (493978)

“…Thereafter, plants were exposed to 1) a gradual temperature decrease from 25/20°C to 13/8 ^oC, over 24 days (0.5°C/day), 2) to a 3 days chilling cycle (3x13/4 ^oC), where 4 ^oC were applied during the night and in the first 4 h of the morning (with light), followed by a rise up to 13 ^oC, throughout the rest of the diurnal period, 3) a rewarming period of 7 days (7x Rec Cold), with the first day after chilling at 20/15 ^oC and the rest at 25/20 ^oC, 4) followed by a fully rewatering of all plants, which were allowed to recover for another period of 7 days (7x Rec Drought). …”

Liver growth factor modulated the expression of phospho-Akt and Bcl2 in the striatum and mesencephalon of 6-OHDA-lesioned rats. by Rafael Gonzalo-Gobernado (430684)

“…<p>As shown in A, the decrease in phospho-Akt/Akt ratio observed in vehicle-treated rats (A, white bar) was prevented 24 hours after the administration of a single injection of LGF (A, lined bar). …”

Data_Sheet_1_Determination of Microbial Maintenance in Acetogenesis and Methanogenesis by Experimental and Modeling Techniques.zip by Fabian Bonk (5826242)

“…We hypothesized that a decrease in dilution rate might select taxa with minimized maintenance expenditure. …”

DDB2, XPC and p53 follow same induction/translocation pattern after UV exposure in NHEK and HCEC. by Justin D. Mallet (3111555)

“…(B) Quantitative analysis of Western blots shows a rapid increase of DDB2 on the CB fraction and a (E) rapid decrease in NS post-UV irradiation (unirradiated control vs 0h post-UV) in both NHEK and HCEC. …”

Flow diagram of exclusion criteria. by Mariet Benade (13943917)

“…Multivariable regression showed that participants with incident hypertension in 2017 were 3.01 (95%CI 1.77, 5.13) times more likely to have a controlled blood pressure compared to those in 2011. …”

Sociodemographic characteristics of the sample. by Lindsey Smith Taillie (3159258)

“…Effects on purchase intentions were smaller, with a 6% decrease for unsustainable products (p = 0.001) and an 8% increase for sustainable products (p<0.001). …”

DataSheet1_Human organoids are superior to cell culture models for intestinal barrier research.docx by Catherine Kollmann (17077822)

“…<p>Loss of intestinal epithelial barrier function is a hallmark in digestive tract inflammation. The detailed mechanisms remain unclear due to the lack of suitable cell-based models in barrier research. …”

Differentially expressed genes in <i>Tnfr</i>-deficient glomeruli compared to wildtype after TNF stimulation. by Anela Taubitz (433585)

“…<p>Expression profiling by microarrays was performed on isolated glomeruli from wildtype, <i>Tnfr1,2</i>−/−, <i>Tnfr1</i>−/− and <i>Tnfr2</i>−/− mice after stimulation with 50 ng/ml TNF for 12 hours ex vivo. <b>A:</b> Significance analysis using SAM detected differential regulation of 290 unique genes in <i>Tnfr1,2</i>−/− glomeruli with at least 1.5-fold difference compared to wildtype (black data points). 219 genes were down-regulated (upper left), and 71 genes were up-regulated (lower right). …”