Supplementary material for “Genetic insights into causal effects of serum lipids and lipid-lowering drug target genes on autoimmune thyroid disease” by Qinnan Zhang (18874897)

“…SMR analysis also showed that APOB expression in subcutaneous adipose tissue is linked to a higher risk of autoimmune thyroiditis. In addition, we also found other target genes had suggestive correlation with autoimmune thyroiditis, such as ANGPTL3 (OR=5.26,95%CI=1.54-17.94; P=0.008), LPL (OR=2.15,95%CI=1.31-3.53; P=0.003) and CETP (OR=0.10,95%CI=0.02-0.48; P=0.005). …”

Table_2_Effects of Dietary Ginsenoside Rg1 Supplementation on Growth Performance, Gut Health, and Serum Immunity in Broiler Chickens.DOCX by Zehe Song (3723604)

“…Our results showed that dietary supplementation of 300 mg/kg ginsenoside Rg1 significantly improved the growth performance for broilers, particularly at the late stage, including an increase in final body weight and decrease of feed conversion ratio (P < 0.05). Additionally, the integrity of intestinal morphology (Villus height, Crypt depth, and Villus height/Crypt depth) and tight junction (ZO-1 and Occludin), and the secretion of sIgA in the intestine were enhanced by the supplementation of Rg1 in chicken diet (P < 0.05). …”

Image_4_Profiling the Urinary Microbiota in Male Patients With Bladder Cancer in China.TIF by Peng Wu (210686)

“…We observed increased bacterial richness (Observed Species, Chao 1 and Ace indexes; cancer vs. control; 120.0 vs. 56.0; 134.5 vs. 68.3; and 139.6 vs. 72.9, respectively), enrichment of some bacterial genera (e.g., Acinetobacter, Anaerococcus, and Sphingobacterium) and decrease of some bacterial genera (e.g., Serratia, Proteus, and Roseomonas) in cancer group when compared to non-cancer group. …”

Data_Sheet_1_SERS-Based Evaluation of the DNA Methylation Pattern Associated With Progression in Clonal Leukemogenesis of Down Syndrome.PDF by Vlad Moisoiu (6032828)

“…Overall, in this study, the area of the 1005 cm^–1 DNA SERS marker band shows a stepwise decrease in DNA global methylation as cells progress from a pre-leukemia to a full-blown acute leukemia, highlighting thus the potential of SERS as an emerging method of analyzing the methylation landscape of DNA in the context of leukemia genesis and progression.…”

Table_13_Muscle-origin creatinine-cystatin C ratio is an osteoporosis marker in individuals with normal renal function: evidence from observational and Mendelian randomization anal... by Pei He (836326)

“…The multivariable logistic regression model showed that the decrease in CCR was associated with a higher risk of osteoporosis/fracture in all models (all P<0.05). …”

Dimolybdenum Paddlewheel Complexes with Cation Binding Sites as Electrolyte Additives to Manipulate the Solid-Electrolyte Interphase at Lithium Metal Anodes by Simon G. Gersib (21432741)

Table_1_Diving Responses in Experienced Rebreather Divers: Short-Term Heart Rate Variability in Cold Water Diving.XLSX by Richard V. Lundell (8382078)

“…</p>Materials and methods<p>To evaluate divers’ ANS responses, short-term (5 min) heart rate variability (HRV) during dives in 2–4°C water was measured. …”

DataSheet1_Field verification of low-level biochar applications as effective ameliorants to mitigate cadmium accumulation into Brassica campestris L from polluted soils.docx by Youchi Zhang (723152)

“…</p><p>Results: Batch adsorption experiments indicated Cd adsorption capacity of three biochars followed the order of RSB (43.5 mg/g) > PMB (33.3 mg/g) > RHB (24.4 mg/g). Field experiment indicated biochar amendments could slightly change soil pH and cation exchange capacity (CEC); yet led to considerable and significant decreases in extractable Cd concentrations [reductions of: 43%–51% (PMB), 29%–35% (RSB) and 17%–19% (RHB)]. …”

Sustained Activation of Akt Elicits Mitochondrial Dysfunction to Block <em>Plasmodium falciparum</em> Infection in the Mosquito Host by Shirley Luckhart (245663)

“…Inhibition of RNOS by co-feeding of the nitric-oxide synthase inhibitor <i>L</i>-NAME at infection abrogated Akt-dependent killing of <i>P. falciparum</i> that begins within 18 h of infection in 3–5 d old mosquitoes. Hence, Akt-induced changes in mitochondrial dynamics perturb midgut homeostasis to enhance parasite resistance and decrease mosquito infective lifespan. …”

Data_Sheet_1_Warming and phosphorus enrichment alter the size structure and body stoichiometry of aquatic gastropods.docx by Tao Wang (12008)

“…To investigate this question, we performed an outdoor mesocosm experiment examining the interaction of warming (a 4.5 °C increase in mean temperature above ambient conditions) and nutrient enrichment (phosphorus addition) on the aquatic gastropods’ community and dominant population (Bellamya aeruginosa). …”

Image_1_Muscle-origin creatinine-cystatin C ratio is an osteoporosis marker in individuals with normal renal function: evidence from observational and Mendelian randomization analy... by Pei He (836326)

“…The multivariable logistic regression model showed that the decrease in CCR was associated with a higher risk of osteoporosis/fracture in all models (all P<0.05). …”

Upregulation of ERK phosphorylation in rat dorsal root ganglion neurons contributes to oxaliplatin-induced chronic neuropathic pain by Toyoaki Maruta (8038673)

“…The paw withdrawal thresholds were assessed at different time-points after the treatment, and a significant decrease was observed 3 and 4 weeks after oxaliplatin treatment as compared to the vehicle treatment (4.4 ± 1.0 vs. 16.0 ± 4.1 g; <i>P</i> < 0.05 and 4.4 ± 0.7 vs. 14.8 ± 3.1 g; <i>P</i> < 0.05, respectively). …”

Table_2_Short-term head-down bed rest microgravity simulation alters salivary microbiome in young healthy men.XLSX by Hui Sun (107933)

“…Non-stimulated whole saliva was collected on day 1 (pre-HDBR), on days 5, 10, and 15 of HDBR, and day 6 of recovery. Salivary pH and salivary flow rate were measured, and the V3–V4 region of the 16S rRNA gene was sequenced and analyzed in 80 saliva samples. …”

Table_1_Muscle-origin creatinine-cystatin C ratio is an osteoporosis marker in individuals with normal renal function: evidence from observational and Mendelian randomization analy... by Pei He (836326)

“…The multivariable logistic regression model showed that the decrease in CCR was associated with a higher risk of osteoporosis/fracture in all models (all P<0.05). …”

DataSheet_1_Autonomic Imbalance Increases the Risk for Non-alcoholic Fatty Liver Disease.docx by Inha Jung (11331284)

“…Time domain [standard deviation of the normal-to-normal interval (SDNN) and root mean square difference (RMSSD)]; frequency domain [total power (TP), low frequency (LF), and high frequency (HF), and LF/HF ratio were analyzed.</p>Findings<p>A total 6,466 participants developed NAFLD within a median of 5.7 years. …”

Effects of TNFα on markers of mitochondrial mass and expression of several effector proteins for mitochondrial biogenesis. by Theodore J. Kalogeris (575591)

“…<p>In separate experiments, HMEC-1 cells in 100 cm plates were incubated with TNFα (1 ng/ml), then 4 separate indices of mitochondrial content were examined. (<b>A</b>) Time course of effect of TNFα on mitochondrial mass as measured using a fluorescent plate assay for uptake of MTG dye. …”

Image_1_Multi-Component Comparative Pharmacokinetics in Rats After Oral Administration of Fructus aurantii Extract, Naringin, Neohesperidin, and Naringin-Neohesperidin.pdf by Jinbin Yuan (2451628)

“…DAS 3.1 software suggests the pharmacokinetic profiles of the five components in rats be depicted as a two-compartment pharmacokinetic model. …”

Table_1_Profiling the Urinary Microbiota in Male Patients With Bladder Cancer in China.xlsx by Peng Wu (210686)

“…We observed increased bacterial richness (Observed Species, Chao 1 and Ace indexes; cancer vs. control; 120.0 vs. 56.0; 134.5 vs. 68.3; and 139.6 vs. 72.9, respectively), enrichment of some bacterial genera (e.g., Acinetobacter, Anaerococcus, and Sphingobacterium) and decrease of some bacterial genera (e.g., Serratia, Proteus, and Roseomonas) in cancer group when compared to non-cancer group. …”

Image_1_Diving Responses in Experienced Rebreather Divers: Short-Term Heart Rate Variability in Cold Water Diving.JPEG by Richard V. Lundell (8382078)

“…</p>Materials and methods<p>To evaluate divers’ ANS responses, short-term (5 min) heart rate variability (HRV) during dives in 2–4°C water was measured. …”

Table_6_Muscle-origin creatinine-cystatin C ratio is an osteoporosis marker in individuals with normal renal function: evidence from observational and Mendelian randomization analy... by Pei He (836326)

“…The multivariable logistic regression model showed that the decrease in CCR was associated with a higher risk of osteoporosis/fracture in all models (all P<0.05). …”