Substrate binding specificity of purified OpuAC. by Justina C. Wolters (207763)

“…<p>Binding was measured using intrinsic protein fluorescence at an OpuAC concentration of ∼0.5 µM. The following substrates were tested: proline (panel A), carnitine (panel B), proline betaine (panel C) and glycine betaine (Panel D–F). …”

Changes in epidemiology of conjunctivitis in Hospital Banco de Olhos de Porto Alegre after the outbreak of the COVID-19 pandemic by Letícia Frossard de Assis Bocchese (16488662)

“…In the same period of 2020, this number was 14.194, a drop of 34.5%. The rate of visits having conjunctivitis as main cause also dropped significantly. …”

Climate Change and the Distribution of Neotropical Red-Bellied Toads (<i>Melanophryniscus</i>, Anura, Amphibia): How to Prioritize Species and Populations? by Caroline Zank (586679)

“…We used the estimated decrease in specific suitable climatic range to set a conservation priority rank for <i>Melanophryniscus</i> species. …”

Assessments of the Inhibitory Effects of YC-1 on hRMVECs. by Michael DeNiro (297385)

“…The effects of addition of VEGF, DMSO, SN50M, SN50, and YC-1 on EC lumen formation over the time course of 24 hours, with the bar graph highlighting EC lumens per high power field [HPF] at 24 hour time point. SN50 and YC-1 treatments significantly [***P<0.001] decreased the number of lumen formed in hRMVECs as compared to their respective controls, SN50M and DMSO, respectively. …”

Introduction of FOXA1 into AB32 cells alters progestin response. by Christine L. Clarke (169388)

“…Red - increased log fold expression, green - decreased log fold expression. (B) FOXA1 protein expression in AB32 cells and parent MCF-10A cells before and after viral transduction, compared with endogenous expression in T-47D cells. …”

Estimating blood pressure from the photoplethysmogram signal and demographic features using machine learning techniques by Chowdhury, Moajjem H.

“…Gaussian process regression (GPR) along with the ReliefF feature selection algorithm outperforms other algorithms in estimating SBP and DBP with a root mean square error (RMSE) of 6.74 and 3.59, respectively. …”
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In-laboratory Study 1. by Eti Ben Simon (12500905)

“…<p>(<b>A</b>) One night of sleep deprivation was associated with a significant decrease in helping desire, relative to the sleep-rested condition, for both circumstances involving strangers (left) and familiar others (right). …”

Nkx2.2 represses the <i>Neurod1</i> promoter in alphaTC1 cells. by Teresa L. Mastracci (280324)

“…Conversely, the Nkx2.2 phosphorylation mutant (S-11-D) results in a significant decrease in H3K4me3 in beta cells, comparable to levels in alpha cells. …”

Mmp10 is necessary for <i>Kras^LA2</i>-induced lung tumorigenesis <i>in vivo.</i> by Roderick P. Regala (168909)

“…Statistical analysis using Mann-Whitney U test revealed a significant decrease in higher grade tumors in <i>Kras^LA2/Mmp10^−/−</i> mice; *p<0.002.…”

Figure 2 by Kazuo Konishi (195884)

“…<p>A) DNA methylation status of thirteen cancer-specific or age-related genes/CpG islands in 16 primary CRCs and matched liver metastasis. …”

Results of MC simulations of VO and agonist infusion. by Johane H. Bracamonte (12883844)

“…<p>Top panels show normalized growth in CellArea for 100 representative simulations (gray lines), with terminal values indicated by black circles; adjacent boxplots reflect the mean, CI50, and CI90 of terminal values for 1000 simulations of a) Untreated VO, c) ISO infusion, and e) AngII infusion. …”

Treatment of gp130^757FF mice with WP1066 reduces tumour size. by Louise M. Judd (185660)

“…Antral tumours in 8 week untreated mice (A) and 10 week DMSO-treated vehicle controls (B) were no different in mean area, however WP1066 treatment resulted in ∼50% smaller tumours (C). …”

Co-expression of PGRN rescues the axonopathy induced by Mt TDP-43 but not Mt SOD1. by Angela S. Laird (360986)

“…<p>A) Staining of primary motor axons with an anti-synaptic vesicle 2 revealed a decrease in axonal length and increase in aberrant branching in embryos expressing Mt TDP-43 compared with Wt TDP-43. …”

Increase of intrinsic apoptosis in irradiated HNSCC cancer stem cells. by Anthony Boivin (298008)

“…<p>After cell sorting, two sub-populations were obtained from the SQ20B carcinoma cell line: CD44⁺ cancer stems cells (A, C, E) and a CD44⁻ side population (B, D, F) which were grown in the SQ20B culture medium for 10 days. …”

Characterization of lipid rafts isolated from the nerve trunks and their role in the organization of GIR. by Caroline Fasano (76332)

“…The low density fraction (3) exhibited high cholesterol content and low protein/cholesterol ratio compared to the high density fractions. b, c, Western blot analysis of the gradient fractions showed the enrichment of the fraction 3 in ganglioside GM1 and annexin II. c, d, decrease in annexin II (Western blot) in the rafts fraction isolated from the nerve trunks and depletion of cholesterol by 10 mM MβCD (mean of four assays from one experiment, see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0000612#s4" target="_blank">methods</a>). …”

Extension, twist and writhe changes of DNA during nucleosome-wrapping. by Chunhong Long (6858428)

“…(B) The mean extension increment resulting from nucleosome wrapping is a function of supercoil and stretching force. …”

Echocardiographic characteristics by patient group based on initial qualitative RV assessment of “normal”, “mild/mod” and “severe” RV enlargement. by Chad S. Weldy (9628603)

“…<p>(A) RV end diastolic area (cm²) (RVEDA) and (B) RV end systolic area (cm²) (RVESA) increased with mild-moderate and severe RV enlargement, (C) right atrial area (cm²) increased with severe RV enlargement, (D) RV fractional area change (RVFAC) showed a trend toward a decrease with severe RV enlargement, (E) RV free wall Lagrangian longitudinal strain (RVLS) showed a trend toward an increase with severe RV enlargement, and (F) LV ejection fraction (LVEF%) was similar in all groups, N = 4-11/group. …”

TSLPR-deficiency and IL-7R blockade alter numbers of thymocytes and splenocytes. by Maarten R. Hillen (760783)

“…Total numbers of splenocytes were decreased in anti-IL-7R treated TSLPR-/- mice compared to PBS treated WT mice (C), associated with a decrease in CD4+ and CD8+ T-cells in the anti-IL-7R treated TSLPR-/- mice (D). …”

Whole-cell [Ca²⁺]_i transients in hiPSC-CMs and their requirement for Ca²⁺ influx via L-type Ca²⁺ channels. by Ilanit Itzhaki (225708)

“…<p>(<b>A</b>) Confocal line-scan images showing changes in intracellular Ca²⁺ in a fluo-4 loaded hiPSC-CM (derived from the hIH1 line). …”

Modeling limb enhancers sequence composition and its integration with chromatin information. by Remo Monti (4379632)

“…(<b>B</b>) Same as (A) but showing AUPRC. (<b>C</b>) Bar plot showing the average coefficient from the LASSO models for those sequence features selected in 9/10 of splits during LASSO training and reported in the top 25% in terms of mean decrease in accuracy, as estimated during RF training. …”