Molecular Dynamics Characterization of Five Pathogenic Factor X Mutants Associated with Decreased Catalytic Activity by Safwat Abdel-Azeim (153436)

Subjects:

Molecular Dynamics Characterization of Five Pathogenic Factor X Mutants Associated with Decreased Catalytic Activity by Safwat Abdel-Azeim (153436)

Subjects:

Time course of central retinal thickness (CRT) in recurrence and non-recurrence groups. by Yasuyuki Sotani (20114144)

“…These values significantly decreased in the first postoperative year to 2.3 ± 2.6, 0.1 ± 0.3, 0.8 ± 1.6, 0, and 3.1 ± 2.8; in the second year to 2.1 ± 2.8, 0.4 ± 1.0, 0.0, 0.1 ± 0.3, and 2.6 ± 2.8; and in the third year to 2.0 ± 2.2, 0, 0.6 ± 1.7, 0.1 ± 0.3, and 2.8 ± 3.5 (Kruskal–Wallis test, p < 0.001; <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0332941#pone.0332941.g007" target="_blank">Fig 7</a>). …”

Values for the calculation of the time-dependent drug concentrations in the system based on observed data found and derived from a variety of sources. by J. Roadnight Sheehan (20141887)

Schematic of the D2 model (standard non-competitive model). by Hidetoshi Urakubo (578508)

Comparison of potential energy minimization curves of hypothetical monomer chains from non-capsid and capsid dimers. by Weimin Wu (505435)

“…<p>Compared are apo 3KXS (A) and liganded 5E0I (B) non-capsid chains with the apo T = 4 1QGT capsid chains (C). …”

MMP-2 production is decreased following ALK5 inhibition. by Rebecca A. Scott (488956)

Down-regulation of BjsR4 under tellurite and iron stresses, and impact of this down-regulation on survival at high iron concentration. by Julia Hahn (3279486)

“…<p><b>A)</b> The steady-state level of BjsR4 is decreased upon addition of tellurite. …”

hsa-let-7e-5p acts as a downstream mediator of circ_0000006 and circ_0000160. by Yong Liu (6908)

Real-time PCR confirmation of randomly selected genes whose expression levels were either increased (red) or decreased (green) by a specific endoxifen concentration. by John R. Hawse (227611)

13 thaxtomin A-resistant mutants were isolated from a screen of 10⁷ mutants. by Chloe Casey (14341756)

Prolonged starvation leads to a delay in cell cycle re-entry and decrease in H3K27ac in Vasa2+/Piwi1+ cells. by Eudald Pascual-Carreras (12115380)

“…Significance levels after one-way ANOVA with Tukey’s HSD for pairwise comparisons are indicated for adjusted <i>p</i> values: *<i>p < </i>0.05, **<i>p < </i>0.01; ****<i>p < </i>0.0001. d: day(s), n.s.: non-significant. See <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3003525#pbio.3003525.s016" target="_blank">S5</a> and <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3003525#pbio.3003525.s017" target="_blank">S6 Tables</a> for mean values and statistical data and <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3003525#pbio.3003525.s020" target="_blank">S1 Data</a> for individual numerical values.…”

IGF1R was phosphorylated on hypoxic GRPs, and knockdown of IGF1 decreased the population of CD133- and Oct4-positive hypoxic GRPs. by Akiko Murakami (515972)

MAP-2 decrease follows the early PSA-NCAM reduction induced by glutamate exposure. by María Fernanda Podestá (639243)

“…(A) Microphotographs of hippocampal neurons in culture doubled stained for MAP-2 and PSA-NCAM. …”

Anti-EBOV GP IgGs Lacking α1-3-Galactose and Neu5Gc Prolong Survival and Decrease Blood Viral Load in EBOV-Infected Guinea Pigs by Olivier Reynard (354756)

“…Compared to control animals treated with IgGs from non-immunized double KO pigs, the anti-EBOV IgGs-treated animals exhibited a significantly prolonged survival and a decreased virus load in blood on day 3. …”

The effect of instilling the ophthalmic solution on the LF/HF ratio and typical cases of fluctuations in the LF/HF ratio over time in the DE and non-DE groups. by Minako Kaido (309626)

“…<p>(A) The LF/HF ratio pre- and post-instillation of ophthalmic solution in the DE and non-DE groups. …”

UNC-62 RNAi decreases expression of collagen genes and increases expression of intestinal genes. by Eric L. Van Nostrand (30730)

“…The histogram indicates the distribution of genes by average fold-change upon <i>unc-62</i> RNAi. For 1699 genes with intestine-enriched expression <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003325#pgen.1003325-McGhee1" target="_blank">[23]</a>, <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003325#pgen.1003325-Pauli1" target="_blank">[33]</a>, <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003325#pgen.1003325-Spencer1" target="_blank">[34]</a> as well as the subset of 291 genes that also decrease expression with age <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003325#pgen.1003325-Budovskaya1" target="_blank">[10]</a>, we determined the average mean-centered fold-change from triplicate RNA-seq experiments of <i>unc-62</i> RNAi as compared to controls. …”

DHT stimulation decreases apoptosis and induces cell proliferation in MDA-MB-453 cells. by Jatin Mehta (703766)

Pathway-Express (PE) performs a pathway level impact analysis and orders the affected pathways in the decreasing order of their expected importance for the given condition (panel 1... by Purvesh Khatri (19219)

PDGF-BB-induced NR4A1 expression is decreased after treatment with the NF-κB inhibitor BAY11-7082. by Glenda Eger (636934)