Different response of visASCs to a micro-local oxygen concentration decrease in metabolically active sites of the adipose tissue. by Wilfredo Oliva-Olivera (301968)

“…However, hypox-visASCs from MS patients show a lower ability to actively participate in or stimulate the formation of microvascular structures, while they favor the accumulation of CD11C⁺ and CD163⁺ macrophages in the adipose tissue through their contribution to the increased tissue levels of MCP1. ↑ Increased response; <b>↓</b> Decreased response; → Hypox-visASCs main response NonMS: obese subjects without metabolic syndrome; MS: obese subjects with metabolic syndrome; visASC: visceral adipose tissue-derived multipotent mesenchymal cells; hypox-visASCs: visASC under hypoxia; NOX5: NADPH Oxidase 5; SDF1α: stromal cell-derived factor 1α; VEGF: vascular endothelial growth factor; MCP1: monocyte chemoattractant protein 1; CD11C⁺, CD163⁺: proinflammatory macrophage cell-surface markers.…”

<i>Ext1</i> mutant lungs exhibit a decrease in SHH-FGF10 signaling. by Hua He (120374)

“…<p>(A) qPCR analysis of key components of FGF signaling pathway in lungs from E14.5. …”

S5 Fig - by Meihui Chen (1670020)

Folding and stability of GDAP1 as affected by CMT mutations. by Aleksi Sutinen (10039145)

Subjects:

Image_5_miR-144-5p and miR-451a Inhibit the Growth of Cholangiocarcinoma Cells Through Decreasing the Expression of ST8SIA4.tif by Wan Fu (3681799)

“…This study aimed to investigate the action mechanism of miR-144-5p and miR-451a in cholangiocarcinoma. We found that miR-144-5p and miR-451a were significantly decreased in cholangiocarcinoma patient samples compared to the adjacent normal bile duct samples. …”

Belinostat decreases both male and female bladder weights in transgenic superficial bladder cancer mice by Michael T Buckley (37161)

“…All bladders were voided of urine prior to weighing. Normal non-transgenic mouse bladders weigh approximately 10.0 mg at the same age, and Ha-transgenic mice with superficial bladder cancer have a 3 fold and higher bladder weight. , Male belinostat-treated mice (n = 4, 327.5 mg average weight) showed a two-fold decrease (50%, p = 0.03) in bladder weight versus control (n = 4, 652.5 mg average weight). , Female belinostat-treated mice (n = 5, 34.0 mg average weight) showed a 36% decrease (p = 0.04) in bladder weight versus control (n = 6, 53.3 mg average weight).…”

C1INH significantly decreased renal C5a cleavage and limited C3b deposition in kidneys subjected to IRI. by Juan S. Danobeitia (4386205)

IFN-beta decreases microglia activation, cytokine release, oxidative stress and prevents axonal damage. by Alessandra di Penta (335812)

Decreased miR-29b/c in GC tissue samples. by He Cui (229445)

Four-fold decrease in [H⁺]_e shifted GLT-1a E_rev by −18 mV at both low and high glutamate concentrations. by Anatoli Y. Kabakov (729047)

“…Arrows show GLT-1a E_rev shifts. <b>(C)</b> Average GLT-1 E_rev shifts at 37.5 μM and 600 μM are approximately equal when [H⁺]_e was decreased from 40 to 10 nM.…”

Four-fold decrease in [K⁺]_e shifted GLT-1a E_rev by +22 mV at both low and high glutamate concentrations. by Anatoli Y. Kabakov (729047)

“…Arrows show GLT-1a E_rev shifts. <b>(C)</b> Average GLT-1 E_rev shifts at 37.5 μM and 600 μM are approximately equal when [K⁺]_e was decreased from 44 to 11 mM.…”

Virion production is significantly decreased by rapamycin treatment. by Lisa A. Nichols (357612)

Quercetin decreases proliferation (A) and induces apoptosis (B) in cultured PASMC from control rats. by Daniel Morales-Cano (668199)

Vectorized siRNA TMPRSS2-ERG IV-SQ impaired tumour growth and restored differentiation <i>in vivo</i>. by Giorgia Urbinati (554921)

“…<p><b>a.</b> SCID mice (n = 5/group) bearing VCaP tumour xenografts were injected intravenously either with NaCl 0.9%, non-vectorized siRNA TMPRSS2-ERG IV, NPs siRNA control-SQ or NPs siRNA TMPRSS2-ERG IV-SQ twice per week during 6 weeks (1.8 mg/kg/mouse cumulative dose). …”

Table_1_v2_A long waiting time from diagnosis to treatment decreases the survival of non-small cell lung cancer patients with stage IA1: A retrospective study.docx by Bin Liu (5899)

“…After adjusting for other confounders, the waiting time was identified as an independent prognostic factor.</p>Conclusions<p>A long waiting time before treatment may decrease the survival of stage IA1 NSCLC patients. …”

The substitution F447L is adaptive for J4_S52-HVR1, while it decreases infectivity of parental J4 and J4_ΔHVR1 HCVcc. by Christina Holmboe Olesen (11154333)

Low concentrations of siRNA TMPRSS2-ERG III and IV impair TMPRSS2-ERG oncogene and oncoprotein levels but not cell viability. by Giorgia Urbinati (554921)

“…<b>a. RT-qPCR analysis:</b> relative TMPRSS2-ERG fusion variants III and IV mRNA levels were analysed and compared to non-treated cells. …”

TGFβ1 expression was increased, and RASAL1 expression was decreased in NTM cells in response to a hypoxic environment. by Fiona McDonnell (2636635)

“…A 0hr Control was set to 100%, and the normoxic and hypoxic results were presented as a percentage of this; Normoxic = 95.5%, Hypoxic = 159.4% (P<0.01). n = 3 *P<0.05, **P<0.01. …”

Transfer of RSV-infected <i>Kdm5b</i>-deficient DCs leads to a decreased pathogenic pulmonary RSV challenge. by Catherine Ptaschinski (756139)

Decreased Brain Levels of Vitamin B12 in Aging, Autism and Schizophrenia by Yiting Zhang (391974)

“…Total Cbl was significantly lower in older control subjects (> 60 yrs of age), primarily reflecting a >10-fold age-dependent decline in the level of MeCbl. …”