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Risk assessment for hospital admission in patients with COPD; a multi-centre UK prospective observational study
Published 2020“…In total, 291 of 714 individuals experienced 762 hospitalised AECOPD during five-year follow up. Poorer performance of SPPB was associated with both higher rate (IRR 1.08 per 1 point decrease, 95% CI 1.01 to 1.14) and increased length of stay (IRR 1.18 per 1 point decrease, 95% CI 1.10 to 1.27) for hospitalised AECOPD. …”
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183
Lithium Decreases Glial Fibrillary Acidic Protein in a Mouse Model of Alexander Disease
Published 2015“…Here we tested whether lithium treatment would decrease levels of GFAP in a mouse model of Alexander disease. …”
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<i>Dmxl2</i> knockdown in INS-1E cells decreases glucose-induced insulin release.
Published 2014“…In the presence of various concentrations of glucose (5 and 20 mM), <i>Dmxl2</i>-siRNA–transfected cells displayed only a small increase in insulin release, at a glucose concentration of 20 mM only, whereas a 2- to 3-fold increase was observed with NT siRNA-transfected cells. …”
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TUDCA decreases ER stress in HOX neonatal rat lungs.
Published 2022“…<p>(<b>A</b>) The expression levels of ER stress markers (P-PERK 0.6±0.1-fold, p<0.001, n = 5; PERK 0.7±0.1-fold, p = 0.00364, n = 5; P-IRE1α 0.6±0.0-fold, p<0.001, n = 5; IRE1α 0.6±0.1-fold, p<0.001, n = 5; GRP78 0.8±0.1-fold, p<0.001, n = 5; cleaved ATF6 0.1±0.0-fold, p<0.001, n = 5; spliced XBP1 0.3±0.0-fold, p<0.001, n = 5; 2 males and 3 females) are all decreased while the N-glycosylated VEGFR2 is increased (3.5±0.2-fold, p<0.001, n = 5) in HOX neonatal lungs at P10 indicating TUDCA can attenuate hyperoxia-induced ER stress. …”
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Prevalence reduction of overall obesity in 2022–2027, according to a decrease in the probability of move up one BMI class and an increase in the probability of move down one BMI cl...
Published 2024“…Scenarios 1 and 2 were built up to obtain a stabilization of the overall obesity prevalence: scenario 1 corresponds to a 22% decrease in the probability of move up one BMI class, and scenario 2 corresponds to a 33% increase in the probability of move down one BMI class. …”
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Top Genes with Significantly Decreased Transcript Levels Systemically During SSTI<sup>1</sup>.
Published 2015“…</p><p><sup>2</sup>Function determined via Entrez (<a href="http://www.ncbi.nlm.nih.gov/" target="_blank">www.ncbi.nlm.nih.gov</a>) or Uniprot (<a href="http://www.uniprot.org/" target="_blank">www.uniprot.org</a>)</p><p><sup>3</sup>LFC = Log Fold Change</p><p>Italicized values indicate transcripts are significantly increased at the indicated time point.…”
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Tunicamycin produces a concentration- and time-dependent decrease in cell viability in SH-SY5Y cells concomitant with caspase-3 activation.
Published 2013“…<p>(A) Treatment of SH-SY5Y cells with tunicamycin (0.1–5µM) for 24 h caused a progressive decrease in cell viability as measured by Calcein AM cleavage assay. …”