Supplementary Material for: The Trajectory of Successful Aging: Insights from Metagenome and Cytokine Profiling by Chulenbayeva L. (17808872)

ZnT1, MT and ZnT4 are all involved in the activation process of TNAP. by Shigeyuki Fujimoto (473814)

“…<p>(<b>A</b>) TNAP activity decreased in DT40 cells deficient in genes coding for c<i>ZnT1</i>, c<i>MT</i> and/or c<i>ZnT4</i> (<i>upper panel</i>). …”

Mst1^−/− mice exhibit blunted MOG-specific proliferative and effector cytokine recall responses in vivo. by Konstantin V. Salojin (567844)

“…(<b>D</b>) Mice treated with an Mst1 inhibitor exhibit decreased severity of EAE. EAE was induced in C57Bl/6-Albino/129SvEv mice (n = 10 per treatment group) by immunization with MOGp35–55 in CFA and treated twice daily with the indicated doses of the Mst1 inhibitor LP-945706 administered by oral gavage in citrate buffed (pH 4.5, 0.1 M) 1% Tween 80 vehicle, starting one day after the onset of disease in 50% of the animals. …”

Effects of JNK3-N-Tat on the downstream effectors of JNK3 in PD models. by Jing Pan (95938)

“…<p>(A) Western blotting analysis of p-c-Jun, T-c-Jun and cytochrome c in SH-SY5Y cell extracts after treatment. …”

Supplementary Material for: Eculizumab Modifies Outcomes in Adults with Atypical Hemolytic Uremic Syndrome with Acute Kidney Injury by Cao M. (4161253)

“…<b><i>Results:</i></b> Thirty-one patients were included (females, 18; sporadic aHUS, 29; mean age, 46 ± 20 years). Twenty-six patients were treated with PE/PI alone, and 5 were deemed to be plasma-resistant and received eculizumab after stopping PE/PI. …”

Colonic Interposition for Salvage Esophagectomy with Supercharging by Mujtaba Mubashir (14142260)

DataSheet1_Identification of biomarkers and potential drug targets in osteoarthritis based on bioinformatics analysis and mendelian randomization.docx by Feng Cheng (124653)

“…Further refinement identified two core genes (ARL4C and GAPDH), whose expression levels were found to decrease in OA pathology and exhibited a protective effect in the MR analysis, thus demonstrating consistent trends. …”

Table2_Identification of biomarkers and potential drug targets in osteoarthritis based on bioinformatics analysis and mendelian randomization.XLSX by Feng Cheng (124653)

“…Further refinement identified two core genes (ARL4C and GAPDH), whose expression levels were found to decrease in OA pathology and exhibited a protective effect in the MR analysis, thus demonstrating consistent trends. …”

Table1_Identification of biomarkers and potential drug targets in osteoarthritis based on bioinformatics analysis and mendelian randomization.XLSX by Feng Cheng (124653)

“…Further refinement identified two core genes (ARL4C and GAPDH), whose expression levels were found to decrease in OA pathology and exhibited a protective effect in the MR analysis, thus demonstrating consistent trends. …”

Supplementary Material for: Hepcidin removal during Continuous Renal Replacement Therapy by Colbert J.F. (17330053)

Results when the prestalk cell motive force is varied are shown. by Erin Flowerday (21440306)

“…For all figures unless otherwise specified, the middle line is the mean of 5 realizations and the shaded region shows the standard deviation and the initial configuration is one prestalk cell.…”

The strategic persistence of users. by Lingfei Wu (453300)

“…<p>Panel A shows the distribution of <i>C</i>_<i>i</i> for each community <i>k</i>, <i>k</i> varies from 1 to 110 (the total number of communities under study). …”

Macrophages Have Distinct Transcriptional Responses to Vacuolar and Cytosolic L. monocytogenes Infection by Jess H Leber (4401)

“…Red indicates an increase in RNA abundance relative to uninfected macrophages, and green indicates a decrease. Genes identified by SAM and at least 4-fold induced in WT macrophages by <i>hly− L. monocytogenes</i> are indicated as targets of the “Vacuolar Response”. …”

Reduction of BMP-signaling in <i>Fgf3</i> mutants partially rescues axis extension. by Matthew J. Anderson (265883)

“…<i>Fgf3</i>^<i>Δ/Δ</i><i>; Bmpr1b</i>^<i>Δ/Δ</i> compound mutants, compared to <i>Fgf3</i>^<i>Δ/Δ</i> mutants show a narrower, more normal neural tube at 28 ss (<b>B</b> compare to <b>A</b>; <b>black brackets</b> indicate measurement of NT width, quantified in <b>C</b>), a decrease in neuroectoderm proliferation as measured by phospho-histone H3 staining (<b>D</b>, 26–27 ss, n = 3 each, percentage represents positive nuclei per total nuclei), an increase in tailbud progenitors (<b>F</b> compare to <b>E</b>; <b>black arrows</b> denote tailbud progenitor domain) and a rostrally shifted, more normal, posterior limit of neural crest cells at 34 ss (<b>H</b> compare to <b>G</b>; <b>red arrows</b> indicate posterior limit of neural crest expansion and somites are marked by <b><i>Uncx4</i>.1</b> expression). …”

Induction of experimental dry eye. by Susan R. Heimer (418710)

“…(A) EDE resulted in significant decreases in tear volume after 2 days. …”

Paraoxon does not alter expression of M2 muscarinic receptor protein. by Becky J. Proskocil (364924)

“…In both cell types, carbachol significantly decreased [³H]-NMS (A and B, open bars), but not [³H]-QNB (C, open bars) binding. …”

Effect of Ang II on AFC. by Reem Ismael-Badarneh (3213921)

“…<p>(A) % Alveolar fluid clearance of the initial instilled volume was decreased in the Ang II groups in a dose dependent manner, from 8.6% ± 0.19 in control rats to 6.66% ± 0.13, 6.15% ± 0.11, 5.03% ± 0.31, 4.42% ± 0.29 and 5.25% ± 0.23 in Ang II (10⁻¹⁰ M, 10^-9M, 10⁻⁸ M, 10⁻⁷ M and 10⁻⁶ M) respectively. * P<0.001 As compared to control group; ** P<0.05 As compared to the rest of 10⁻¹⁰ M and 10⁻⁹ M Ang II treated groups. …”

Microglial migration increases long after the electrical silence associated with spreading depression. by Yelena Y. Grinberg (223907)

“…Specific microglial cell counts for SD movies (<i>n</i> = 5) were 0–16 cells per movie with a mean ± SEM of 7.60±2.86 cells/movie. …”

Deletion of <i>bcwcl1</i> and overexpression of the WCC affect the response to oxidative stress. by Paulo Canessa (503820)

“…Both strains were incubated for 3 d on MM (minimal medium) supplemented with 5 g/l ascorbate. Mean values ± SEM were calculated from five colonies per strain in each condition. …”

Seasonal patterns of Asthma medication fills among diverse populations of the United States by Kedir N. Turi (4866565)