The VPS C846G mutation decreases the stability of VPS11 protein. by Jinglan Zhang (401545)

B-THP-Ts bind to C-terminal GFP-PTP tagged F₁ α- and β- subunits. by Lindsay B. Tulloch (1266861)

Supplementary Material for: Intestinal Vascular Endothelial Growth Factor Is Decreased in Necrotizing Enterocolitis by Sabnis A. (4149406)

Fig 2A–2C and 2G–2L Data. by Kevin D. Gaitonde (15411707)

Subjects:

A genetic variant in human FIRE is associated with a decreased interferon response in myeloid cells. by Anaïs Assouvie (9600529)

Longer polyQ sequences decrease the transcriptional activity of AR. by Carlos M. Roggero (11909585)

FK866 treatment causes a time dependent decrease in cellular NAD⁺/NADH and NADP⁺/NADPH content. by Gerda Venter (559404)

Vitamin C decreases the obesogenic and hyperglycemic effect of invert sugar in prediabetic rats by Patrícia MOLZ (6744857)

Repurposing of a Nucleoside Scaffold from Adenosine Receptor Agonists to Opioid Receptor Antagonists by Dilip K. Tosh (1668115)

“…In an effort to increase OR and decrease AR affinity by structure activity analysis of this series, antagonist activity at κ-(K)­OR appeared in 5′-esters (ethyl <b>24</b> and propyl <b>30</b>), which retained TSPO interaction (μM). 7-Deaza modification of C2-(arylethynyl)-5′-esters but not 4′-truncation enhanced KOR affinity (MRS7299 <b>28</b> and <b>29</b>, <i>K</i>_i ≈ 40 nM), revealed μ-OR and DOR binding, and reduced AR affinity. …”

Repurposing of a Nucleoside Scaffold from Adenosine Receptor Agonists to Opioid Receptor Antagonists by Dilip K. Tosh (1668115)

“…In an effort to increase OR and decrease AR affinity by structure activity analysis of this series, antagonist activity at κ-(K)­OR appeared in 5′-esters (ethyl <b>24</b> and propyl <b>30</b>), which retained TSPO interaction (μM). 7-Deaza modification of C2-(arylethynyl)-5′-esters but not 4′-truncation enhanced KOR affinity (MRS7299 <b>28</b> and <b>29</b>, <i>K</i>_i ≈ 40 nM), revealed μ-OR and DOR binding, and reduced AR affinity. …”

Repurposing of a Nucleoside Scaffold from Adenosine Receptor Agonists to Opioid Receptor Antagonists by Dilip K. Tosh (1668115)

“…In an effort to increase OR and decrease AR affinity by structure activity analysis of this series, antagonist activity at κ-(K)­OR appeared in 5′-esters (ethyl <b>24</b> and propyl <b>30</b>), which retained TSPO interaction (μM). 7-Deaza modification of C2-(arylethynyl)-5′-esters but not 4′-truncation enhanced KOR affinity (MRS7299 <b>28</b> and <b>29</b>, <i>K</i>_i ≈ 40 nM), revealed μ-OR and DOR binding, and reduced AR affinity. …”

Repurposing of a Nucleoside Scaffold from Adenosine Receptor Agonists to Opioid Receptor Antagonists by Dilip K. Tosh (1668115)

“…In an effort to increase OR and decrease AR affinity by structure activity analysis of this series, antagonist activity at κ-(K)­OR appeared in 5′-esters (ethyl <b>24</b> and propyl <b>30</b>), which retained TSPO interaction (μM). 7-Deaza modification of C2-(arylethynyl)-5′-esters but not 4′-truncation enhanced KOR affinity (MRS7299 <b>28</b> and <b>29</b>, <i>K</i>_i ≈ 40 nM), revealed μ-OR and DOR binding, and reduced AR affinity. …”

Exercise decreased the increased expression of cofilin in the cortex during aging. by Yan Li (23143)

Image_1_miR-144-5p and miR-451a Inhibit the Growth of Cholangiocarcinoma Cells Through Decreasing the Expression of ST8SIA4.tif by Wan Fu (3681799)

“…This study aimed to investigate the action mechanism of miR-144-5p and miR-451a in cholangiocarcinoma. We found that miR-144-5p and miR-451a were significantly decreased in cholangiocarcinoma patient samples compared to the adjacent normal bile duct samples. …”

Image_4_miR-144-5p and miR-451a Inhibit the Growth of Cholangiocarcinoma Cells Through Decreasing the Expression of ST8SIA4.tif by Wan Fu (3681799)

“…This study aimed to investigate the action mechanism of miR-144-5p and miR-451a in cholangiocarcinoma. We found that miR-144-5p and miR-451a were significantly decreased in cholangiocarcinoma patient samples compared to the adjacent normal bile duct samples. …”

Image_3_miR-144-5p and miR-451a Inhibit the Growth of Cholangiocarcinoma Cells Through Decreasing the Expression of ST8SIA4.tif by Wan Fu (3681799)

“…This study aimed to investigate the action mechanism of miR-144-5p and miR-451a in cholangiocarcinoma. We found that miR-144-5p and miR-451a were significantly decreased in cholangiocarcinoma patient samples compared to the adjacent normal bile duct samples. …”

Image_2_miR-144-5p and miR-451a Inhibit the Growth of Cholangiocarcinoma Cells Through Decreasing the Expression of ST8SIA4.tif by Wan Fu (3681799)

“…This study aimed to investigate the action mechanism of miR-144-5p and miR-451a in cholangiocarcinoma. We found that miR-144-5p and miR-451a were significantly decreased in cholangiocarcinoma patient samples compared to the adjacent normal bile duct samples. …”

Disruption of the interaction between AKIP 1A and PKAc decreases phosphorylation of p65 at serine 276 in the cytosol. by Charles C. King (156152)

Data_Sheet_1_Elevated temperature and decreased salinity impacts on exogenous Vibrio parahaemolyticus infection of eastern oyster, Crassostrea virginica.zip by Omario M. A. Ricketts (16450914)

“…Specifically, we examined whether an increase in water temperature and/or decrease in salinity would impair oyster resistance to V. parahaemolyticus, a human food and waterborne pathogen. …”

mTOR inhibition with rapamycin decreases MEC survival and branching. by Meghan M. Morrison (683792)