Retinal ganglion cell layer of New World monkeys. by José Augusto Pereira Carneiro Muniz (212787)

“…The retinal ganglion cell layer is shown at three increasing eccentricities: 5 mm (<b>B</b>), 2 mm (<b>C</b>), and 1 mm (<b>D</b>) temporal to the fovea. …”

Projection-resolved optical coherence tomography angiography (PR-OCTA) of hard exudates. by Alaa E. Fayed (6703916)

“…There is gradual decrease in the flow signal intensity with increasing PR-OCTA threshold from 0.3 to 0.5 (yellow ellipses), manifested by a decrease in red pixel percentage from 38.4% to 34.5%. …”

Impact of Baseline BMI on Glycemic Control and Weight Change with Metformin Monotherapy in Chinese Type 2 Diabetes Patients: Phase IV Open-Label Trial by Linong Ji (131708)

“…</p> <p>Results</p><p>Mean HbA_1c decreases at week 16, adjusted for baseline values, were –1.84%, –1.78% and –1.78% in normal-weight, overweight and obese patients, (<i>P</i> = 0.664); body weight decreased by 2.4%, 3.9% and 3.5%, respectively. …”

Fig 1 - by Leo Zeitler (13775500)

“…Relative fitness (D) decreased from core to edge with similar values across outcrossers and selfers: , reflecting a relative loss of fitness as compared to the core of 29.1%, 29.8%, 32.4%, and 31.7% respectively for <i>σ</i> = 0, 0.5, 0.95, and 1.…”

Inhibition of SDF-1 signaling alleviates chronic skin inflammation and inhibits leukocyte migration towards SDF. by Silvana Zgraggen (546104)

“…<p>(A) On day -5, hemizygous K14 VEGF-A transgenic mice (n = 14) were sensitized with 2% oxazolone and challenged on day 0 with 1% oxazolone on the ears. …”

Image1_Antidiabetic Activity of Elephant Grass (Cenchrus Purpureus (Schumach.) Morrone) via Activation of PI3K/AkT Signaling Pathway, Oxidative Stress Inhibition, and Apoptosis in... by Oluwafemi Adeleke Ojo (12176981)

“…</p><p>Results: This in vitro study showed inhibitory potency of Cenchrus purpureus extract (AECPS) as compared with the positive controls. AECPS showed a gradual decrease in alloxan-induced increases in FBG, total cholesterol (TC), triglycerides (TG), low density lipoprotein (LDL-c), G6P, F-1,6-BP, malondialdehyde (MDA), IL-6, TNF-α, and NF-ĸB and increased alloxan-induced decreases in liver glycogen, hexokinase, and high density lipoprotein (HDL-c). …”

Fig 3 - by Theresa Casey (211702)

“…<p>(a)Western blot analysis of BMAL1 protein abundance in HC11 and monoclonal colonies (1A, 1B, 1C, 2A, 2B, 2C, 2D) established from CRISPR-CAS transfected with guide RNA (gRNA) targeting BMAL1 gene post monoclonal selection. …”

Undetermined variants. by Maxime Godfroid (9444020)

“…<p>(A) Parsimony scores of SNPs having at most five gaps (i.e., SNPs that are undetermined in at most five samples), (B) Parsimony scores of SNPs having between six and 20 gaps. …”

Pharmacological manipulations and neuron model. by Dominique Martinez (229854)

“…The durations of the two phases were plotted <i>versus</i> the normalized decrease in SK-like conductance (Δg_SK at top axis, with g ranging from <i>gmin</i> = 0.05 µS to <i>gmax</i> = 0.5 µS).…”

The PI3K/Akt- and NO-related pathways contribute to EPC tube formation affected by oxLDL. by Feng-Yen Lin (143413)

“…In contrast, 10–50 μg/mL oxLDL had decreasing production of NO observed (n = 5). (D) EPCs were pretreated with L-NAME or LY294002 for 1 hour prior to treatment with 5 μg/mL oxLDL for 24 hours, or pretreated with SNAP or NAC for 1 hour prior to treatment with 50 μg/mL oxLDL for 24 hours. …”

Obesity and leptin resistance in <i>Bbs4^−/−</i> mice are rescued by <i>LAP-BBS4</i>. by Xitiz Chamling (390467)

“…<p>A) 10 mice per group <b>(</b>5 male and 5 female) mice were weighed every month to 6 months of age. …”

Nucleosome occupancy comparison between SF and BF. by Chenyu Tao (3857587)

“…Colors indicate the change in nucleosome occupancy in each 10 kb region between the two samples. Red indicates a ≥ 1.5-fold increase in nucleosome occupancy of SF, green indicates a ≥ 1.5-fold decrease in nucleosome occupancy of SF, grey indicates the no reads mapped region, and yellow indicates regions with other cases. …”

Immunodepletion of the sEV fractions derived from human blood. by Xiaoman Zhang (1885492)

“…Although significant accumulation of ApoB and ApoA1 on the beads after immunodepletion with antibodies against these lipoproteins was observed, only a slight decrease in the protein level of ApoA1, and no decrease in ApoB was observed. …”

Lethe overexpression reduces NOX2 gene expression. by Carlos Zgheib (311460)

“…<p>RNA analyses by RT-qPCR (mean ± SD, n = 5 per group) showed no significant change in SOD2 (A), SOD3 (B), and Catalase (C) gene expression, while NOX2 (D) gene expression was significantly decreased following overexpression of Lethe in the RAW macrophages transfected with pcDNA-Lethe.…”

Measuring intracellular viscosity. by Kelly Aubertin (502991)

“…For these two examples, the viscosity around the observed chain slightly increased after treatment, from </p><p></p><p></p><p><mn>0.11</mn><mo>±</mo><mn>0.01</mn> Pa.s</p><p></p><p></p>to0.18±0.03 Pa.s Pa.s in the mTHPC case, and from <p></p><p></p><p><mn>0.25</mn><mo>±</mo><mn>0.05</mn> Pa.s</p><p></p><p></p>to <p></p><p></p><p><mn>0.55</mn><mo>±</mo><mn>0.04</mn> Pa.s</p><p></p><p></p>in the TPCS2a case. (B) Mean viscosity (averaged over 25 independent measurements at least) is shown for each condition (for unlabeled control cells, for unlabeled cells exposed for 20s, for unlabeled cells treated with nocodazole (10µM, 30min), for cells treated with m-THPC (without exposition, or exposed for 1s and 5s), for cells treated with TPCS2a (without exposition, or exposed for 1s, 5s, and 20s). …”

NOS network and reporters expression for cell lines grown 2i conditions. by Elsa Abranches (261932)

“…While, for both cell lines, <i>Oct4</i> and <i>Sox2</i> expression does not change significantly (p-value >0.10), both <i>VNP</i> and <i>Nanog</i> expression levels show a 2–3 fold increase (*p-value <0.03). This change is accompanied by a decrease in the expression levels of <i>Fgf5</i> and <i>Dusp6</i> when FGF/ERK signaling is abolished (**p-value <5.8×10⁻⁶). …”

Table_1_Use of Prazosin for Pediatric Post-Traumatic Stress Disorder With Nightmares and/or Sleep Disorder: Case Series of 18 Patients Prospectively Assessed.docx by Vladimir Ferrafiat (9154643)

“…</p>Results<p>Among the 18 patients (10 girls and 8 boys), 13 (72%) had experienced sexual abuse and 5 (28%) family violence. After 1 month of treatment with a mean prazosin dose of 2.16 ( ± 0.6) mg/day, the CGI-S score significantly decreased from 5.3 ( ± 0.9) to 2.9 ( ± 0.7) (improvement of 43%). …”

Reproduction of Black Soldier Fly (Diptera: Stratiomyidae) under Different Adult Densities and Light Regimes by Zhongyu Liu (9197852)

Clock controlled pre-mRNA and protein expression in SCN during low light at ZT12. by Heather Dehlin Scoma (343527)

“…<p><b>A.</b> Un-spliced mRNA transcripts for <i>Per1</i> (Mean ±SEM, n = 3 animals), <i>Rev-erbα</i> (n = 6), <i>Dbp</i> (n = 6) and <i>cFos</i> (n = 3) were measured by RT-qPCR from isolated SCN during exposure to low irradiance light (log irradiance 3) from ZT12 to ZT16. …”

Differentially expressed genes in <i>Tnfr</i>-deficient glomeruli compared to wildtype after TNF stimulation. by Anela Taubitz (433585)

“…<b>B:</b> In <i>Tnfr1</i>−/− mice 219 differentially regulated genes were identified, with lower expression of 159 genes and increased expression of 60 genes. <b>C:</b> In <i>Tnfr2</i>-deficient glomeruli only 5 genes were differentially expressed, all of them with decreased expression compared to wildtype. …”