Pharmacodynamic effects of dasatinib on the Src pathway. by Aaron J. Scott (4412410)

“…<p>A) Treatment with dasatinib (0.8 μmol/L) at 0.5h, 1h, 2h, 4h, and 8h significantly reduced the activation of Src, FAK and paxillin at all time points examined in the HCT116 sensitive CRC cell line when compared to control. …”

Data_Sheet_4_Flavonoid Derivative of Cannabis Demonstrates Therapeutic Potential in Preclinical Models of Metastatic Pancreatic Cancer.pdf by Michele Moreau (5726120)

“…<p>Pancreatic cancer is particularly refractory to modern therapies, with a 5-year survival rate for patients at a dismal 8%. …”

Image 2_Spatial deciphering of the transcriptomic heterogeneity of tumor spread through air spaces in lung cancer.tif by Wenhao Wang (515852)

“…Meanwhile, an increase in CD4 T memory cells and a decrease in B cells were observed in the tumor immune microenvironment of STAS. …”

Image 4_Spatial deciphering of the transcriptomic heterogeneity of tumor spread through air spaces in lung cancer.tif by Wenhao Wang (515852)

“…Meanwhile, an increase in CD4 T memory cells and a decrease in B cells were observed in the tumor immune microenvironment of STAS. …”

Effect of Particle Shape on Capillary Forces Acting on Particles at the Air–Water Interface by Nirmalya Chatterjee (171737)

“…The particles (5 mm nominal size) were made of polyacrylate and were fabricated using a 3D printer. …”

The effect of hydroxychloroquine on lupus erythematosus-like skin lesions in MRL/lpr mice by Tatsuya Shimomatsu (1545943)

“…The average number of mast cells was 81, 50, and 12 (magnification, ×100), the mortality rate was 24%, 8%, and 9% and the mean body weight gain was 4.6 g, 8.0 g and 5.1 g, respectively.</p> <p><i>Conclusions</i>: HCQ was demonstrated to decrease the appearance of LE-like lesions and the number of mast cells in the dermis. …”

The cephalic lateral line system of temperate perches (Perciformes: Percichthyidae) from Argentinean Patagonia by Rocío M. Vega (12844196)

“…Specimens were bleached in 5% H2O2 and the canal systems of their cephalic lateral line were filled with hematoxylin. …”

Molecular Tectonics. Disruption of Self-Association in Melts Derived from Hydrogen-Bonded Solids by Danielle Boils (2707627)

“…In tectons <b>3</b>−<b>5</b>, for example, simple triaminotriazine groups grafted to a nominally tetrahedral tetraphenylmethyl core form intermolecular hydrogen bonds according to reliable motifs, and crystallization thereby leads to the formation of porous three-dimensional networks. …”

Droplet Microfluidic System with On-Demand Trapping and Releasing of Droplet for Drug Screening Applications by Matthew Courtney (3396641)

“…This work demonstrates a droplet microfluidic platform that has the potential to significantly reduce the reagent consumption and shorten the reaction and analysis time by utilizing nanoliter-sized droplets as a replacement of wells. …”

raw data of "Helicobacter hepaticus promotes hepatic steatosis through CdtB-induced mitochondrial stress and lipid metabolism reprogramming" by Quan Zhang (20376574)

“…Furthermore, we identify that CdtB translocates to mitochondria with the assistance of Hsp90, leading to a decrease in the activity of mitochondrial respiratory complex V due to its interaction with ATP5A1. …”

Data_Sheet_3_Flavonoid Derivative of Cannabis Demonstrates Therapeutic Potential in Preclinical Models of Metastatic Pancreatic Cancer.pdf by Michele Moreau (5726120)

“…<p>Pancreatic cancer is particularly refractory to modern therapies, with a 5-year survival rate for patients at a dismal 8%. …”

Predicted Functional RNAs within Coding Regions Constrain Evolutionary Rates of Yeast Proteins by Charles D. Warden (85098)

“…We then analyzed the impact of coding fRNAs on the evolutionary rate of protein-coding genes because a decrease in evolutionary rate implies constraint due to biological functionality. …”

Data Sheet 1_Spatial deciphering of the transcriptomic heterogeneity of tumor spread through air spaces in lung cancer.zip by Wenhao Wang (515852)

“…Meanwhile, an increase in CD4 T memory cells and a decrease in B cells were observed in the tumor immune microenvironment of STAS. …”

Cryopreservation Causes Genetic and Epigenetic Changes in Zebrafish Genital Ridges by Marta F. Riesco (425309)

“…Our results indicated that cryopreservation produced a decrease in most of the zebrafish studied transcripts (<i>cxcr4b, pou5f1, vasa</i> and <i>sox2</i>) and upregulation of heat shock proteins (<i>hsp70, hsp90</i>). …”

Chromosome Segregation Analysis in Human Embryos Obtained from Couples Involving Male Carriers of Reciprocal or Robertsonian Translocation by Ahmet Yilmaz (132195)

“…Involvement of non-acrocentric chromosome(s) or terminal breakpoint(s) in reciprocal translocations was associated with an increase in the percent of embryos consistent with adjacent 1 but with a decrease in 3∶1 segregation. Similar results were obtained in the analysis of nontransferred embryos donated for research. 3∶1 segregation was the most frequent segregation type in both day 3 (31%) and spare (35%) embryos obtained from carriers of t(11;22)(q23;q11), the only non-random REC with the same breakpoint reported in a large number of unrelated families mainly identified by the birth of a child with derivative chromosome 22. …”

Image_1_Flavonoid Derivative of Cannabis Demonstrates Therapeutic Potential in Preclinical Models of Metastatic Pancreatic Cancer.JPEG by Michele Moreau (5726120)

“…<p>Pancreatic cancer is particularly refractory to modern therapies, with a 5-year survival rate for patients at a dismal 8%. …”

Zooming in: Structural Investigations of Rheologically Characterized Hydrogen-Bonded Low-Methoxyl Pectin Networks by Bradley W. Mansel (1514149)

Image_2_Flavonoid Derivative of Cannabis Demonstrates Therapeutic Potential in Preclinical Models of Metastatic Pancreatic Cancer.png by Michele Moreau (5726120)

“…<p>Pancreatic cancer is particularly refractory to modern therapies, with a 5-year survival rate for patients at a dismal 8%. …”

Incidence of stalk rots in corn hybrids influenced by sowing time and nitrogen rates by Juliano Berghetti (6515036)

“…A decrease in the incidence of stalk rot was observed in the hybrid AG9025 PRO3 as nitrogen rates increased, but this behavior was not clearly observed in the hybrid 30F53 VYH.…”

Effect of Dapagliflozin on Renal and Hepatic Glucose Kinetics in T2DM and NGT Subjects by Xi Chen (35903)

“…Following DAPA, EGP increased in both T2D and NGT from baseline to 240 minutes, while there was a significant time-related decrease after placebo in T2D. …”