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66641
Antibody titers and cytokines production against SLA after infection in control and vaccinated mice groups.
Published 2015“…For cytokine determinations spleen cells were cultured for 72 h at 37°C, 5% CO<sub>2</sub> in the absence or in the presence or soluble <i>Leishmania</i> antigen (SLA; 12 μg/ml). …”
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66642
Novel, selective EPO receptor ligands lacking erythropoietic activity reduce infarct size in acute myocardial infarction in rats
Published 2016“…In a pilot study, EPO at 100 U/mL significantly decreased cell death compared to vehicle (33.8 ± 2.3% vs. 40.3 ± 1.5%, p < 0.05) in rat neonatal cardiomyocytes subjected to simulated ischemia/reperfusion. …”
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66643
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66644
Establishment of readout and pharmacokinetics.
Published 2020“…ZH3 mice exhibited a decrease in sciatic nerve Egr2 levels and a concomitant increase in GFAP and c-Jun levels. …”
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66645
Determinant of Selective Removal (DSR) sequences can reduce protein levels expressed from P<i><sub>urg1lox</sub></i>.
Published 2013“…The strains were cultured in EMM+L to ∼5×10<sup>6</sup> cells at 30°C (uracil absent - P<i><sub>urg1lox</sub></i> OFF). …”
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66646
Table_1_Immune Monitoring of Patients With Primary Immune Regulation Disorders Unravels Higher Frequencies of Follicular T Cells With Different Profiles That Associate With Alterat...
Published 2020“…These alterations confirmed the existence of an imbalance in the cTfh1/cTfh17 ratio in these diseases. In addition, we unraveled a marked dysregulation in the B cell compartment, characterized by a prevalence of transitional and naïve B cells in STAT1 GOF and CVID patients, and of switched-memory B cells and plasmablast cells in the STAT5b deficient patient. …”
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66647
High bone mass and functional bone resorption defect in 3-month-old <i>Sema4D</i>-deficient females.
Published 2011“…D/ Urinary deoxypyridinoline (DPD) cross-links elimination was significantly lower in <i>Sema4D</i> −/− animals compared to WT, indicating that the <i>Sema4D</i> deficiency results in a functional decrease in bone resorption n = 8 for WT and n = 14 for <i>Sema4D−/−</i> mice. …”
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66648
Novel Quinazolinone MJ-29 Triggers Endoplasmic Reticulum Stress and Intrinsic Apoptosis in Murine Leukemia WEHI-3 Cells and Inhibits Leukemic Mice
Published 2012“…Our results indicated that a concentration-dependent decrease of cell viability was shown in MJ-29-treated cells. …”
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66649
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66650
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66651
Artisanal Green Turtle, <i>Chelonia mydas</i>, Fishery of Caribbean Nicaragua: I. Catch Rates and Trends, 1991–2011
Published 2014“…Explanations for the apparent discrepancy between the increasing trend at Tortuguero and decreasing catch rate trends in Nicaragua include: i) an increase in reproductive output, ii) insufficient time has passed to observe the impact of the fishery on the rookery due to a time lag, iii) changes in other segments of the population have not been detected since only nesting activity is monitored, iv) the expansive northern Nicaragua foraging ground may provide a refuge for a sufficient portion of the Tortuguero rookery, and/or v) a larger than expected contribution of non-Tortuguero rookeries occurring in Nicaragua turtle fishing areas. …”
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66652
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66653
Methylation and Loss of Secreted Frizzled-Related Protein 3 Enhances Melanoma Cell Migration and Invasion
Published 2011“…We found that recombinant SFRP3 could inhibit Wnt5a signaling, and that it inhibited melanoma cell migration and invasion in a Wnt5a-dependent manner.…”
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66654
Image_1_Kinetics of Phenotypic and Functional Changes in Mouse Models of Sponge Implants: Rational Selection to Optimize Protocols for Specific Biomolecules Screening Purposes.TIF
Published 2020“…Here, the changes in histological/morphometric, immunophenotypic and functional features of infiltrating leukocytes (LEU) were assessed in sponge implants for Swiss, BALB/c, and C57BL/6 mice. A gradual increase of fibrovascular stroma and a progressive decrease in LEU infiltration, mainly composed of polymorphonuclear cells with progressive shift toward mononuclear cells at late time-points were observed over time. …”
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66655
Image_1_Kinetics of Phenotypic and Functional Changes in Mouse Models of Sponge Implants: Rational Selection to Optimize Protocols for Specific Biomolecules Screening Purposes.TIF
Published 2021“…Here, the changes in histological/morphometric, immunophenotypic and functional features of infiltrating leukocytes (LEU) were assessed in sponge implants for Swiss, BALB/c, and C57BL/6 mice. A gradual increase of fibrovascular stroma and a progressive decrease in LEU infiltration, mainly composed of polymorphonuclear cells with progressive shift toward mononuclear cells at late time-points were observed over time. …”
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66656
<i>Ex vivo</i> effect of P140 peptide on MRL/lpr PBL apoptosis.
Published 2009“…Granzyme-B inhibitor I (20 µMZ-AAD-CMK; see also insert c2), perforin inhibitor (5 nM concanamycin A) and caspase inhibitors (20 µM Z-VAD-FMK) were added 30 min post-P140 incubation to analyze the involvement of these pathways. …”
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66657
Table_6_Auxin-regulated timing of transition from vegetative to reproductive growth in rapeseed (Brassica napus L.) under different nitrogen application rates.XLSX
Published 2022“…In this research, the mechanisms of different nitrogen (N) application rates (low N, N1; normal N, N2; and high N, N3) on different FM development stages triggering the regulation of FM differentiation genes through the auxin biosynthetic and signal transduction were investigated. We found that the stage of FM differentiation, which was identified through a stereomicroscope and scanning electron microscope, came 4 and 7 days earlier under high N rate than under normal and low N levels, with the seed yield increased by 11.1 and 22.6%, respectively. …”
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66658
Table_2_Auxin-regulated timing of transition from vegetative to reproductive growth in rapeseed (Brassica napus L.) under different nitrogen application rates.XLS
Published 2022“…In this research, the mechanisms of different nitrogen (N) application rates (low N, N1; normal N, N2; and high N, N3) on different FM development stages triggering the regulation of FM differentiation genes through the auxin biosynthetic and signal transduction were investigated. We found that the stage of FM differentiation, which was identified through a stereomicroscope and scanning electron microscope, came 4 and 7 days earlier under high N rate than under normal and low N levels, with the seed yield increased by 11.1 and 22.6%, respectively. …”
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66659
Table_1_Auxin-regulated timing of transition from vegetative to reproductive growth in rapeseed (Brassica napus L.) under different nitrogen application rates.XLS
Published 2022“…In this research, the mechanisms of different nitrogen (N) application rates (low N, N1; normal N, N2; and high N, N3) on different FM development stages triggering the regulation of FM differentiation genes through the auxin biosynthetic and signal transduction were investigated. We found that the stage of FM differentiation, which was identified through a stereomicroscope and scanning electron microscope, came 4 and 7 days earlier under high N rate than under normal and low N levels, with the seed yield increased by 11.1 and 22.6%, respectively. …”
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66660
Table_3_Auxin-regulated timing of transition from vegetative to reproductive growth in rapeseed (Brassica napus L.) under different nitrogen application rates.xls
Published 2022“…In this research, the mechanisms of different nitrogen (N) application rates (low N, N1; normal N, N2; and high N, N3) on different FM development stages triggering the regulation of FM differentiation genes through the auxin biosynthetic and signal transduction were investigated. We found that the stage of FM differentiation, which was identified through a stereomicroscope and scanning electron microscope, came 4 and 7 days earlier under high N rate than under normal and low N levels, with the seed yield increased by 11.1 and 22.6%, respectively. …”