Exposure to low CO₂ levels decreases ER cholesterol levels. by Nityanand Bolshette (17396845)

“…<b>(D, E)</b> The free cholesterol and cholesterol ester levels in the ER membrane from the cells as in <b>(C)</b>, were quantified with shotgun lipidomics analysis (see <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002367#pbio.3002367.s007" target="_blank">S7 Fig</a> and <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002367#pbio.3002367.s012" target="_blank">S5 Table</a>) (mean ± SE, <i>n</i> = 3 independent experiments, **<i>P</i> < 0.01, *<i>P</i> < 0.05, nonsignificant (ns) two-sided Student’s <i>t</i> test). …”

Nasal mucociliary clearance was decreased in <i>Ttll1</i>^−/− mice. by Toshiyuki Iwata (419270)

“…In the <i>Ttll1</i>^−/− mice, a larger amount of Evans blue persisted in the nasal cavity and a lesser amount was swallowed compared with that in the wild-type (WT) mice (mean ± SEM, n = 5, *P < 0.005 by two-tailed Student's t test).…”

Expression of neurotrophins and their receptors was decreased in <i>Slitrk6</i>-deficient inner ear. by Kei-ichi Katayama (257931)

“…(C) Both Ntrk2 and Ntrk3 proteins in the cochlea were significantly decreased in <i>Slitrk6</i>-knockout mice. …”

Behavioral response to ambiguous conditioned fear cues is decreased in adult neurogenesis-deficient mice. by Lucas R. Glover (3912628)

Stroma decreases spheroid size by decreasing cell width. by Karen F. Chambers (224337)

Aspirin decreases expression of NFκB and β-catenin in colon cancer cells. by Satya Pathi (301408)

“…<p>Decreased p65/p50 in RKO (A) and SW480 (B) cells. Cells were treated for 48 hr with 5 or 10 mM, and whole cell, nuclear and cytosolic extracts were analyzed by western blot analysis as described in the <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0048208#s3" target="_blank">Experimental Procedures</a>. …”

DHT increases whereas orchidectomy decreases the weight and cross sectional area of hindlimb muscles. by Young-Eun Yoo (323357)

“…<b>A:</b> In WT mice, DHT increased the GN weight by 7% (212.4±8.8 mg), whereas orchidectomy decreased it by 14% (171.4±9.0 mg) compared with control WT mice (198.4±5.5 mg). …”

GBE did not modify cell morphology but decreased reactive oxygen species (ROS) levels. by Virginie Rhein (243241)

“…<p>Morphological analysis of vector control and APP cells showed neuroblast-like morphology with differentiated perikaria (<i>arrows</i>) and occasional short neurites (<i>arrowheads</i>). <b>A</b>) Transfection of SH-SY5Y cells with cDNAs (pCEP4 vector) containing the vector alone or the entire coding region of wild-type human APP (APP cells) and <b>B</b>) GBE treatment (100 µg/ml; 24 h) did not significantly change general cell morphology. …”

Rapamycin decreases Schwann cell markers, whereas statin induces Schwann cell markers. by Andrea Preitschopf (629851)

Decrease in adhesion during early development of <i>Dictyostelium discoideum</i>. by Marco Tarantola (102609)

KCl treatment increases Elk1 SUMOylation and decreases katanin-p60 expression. by Ece Selçuk (436963)

Decreased neutrophil levels in HIF^C mice correlates to decreased production of CXCL1 and not migration defects. by Kelly M. Shepardson (404375)

Reciprocal increase in 5mC and decrease in 5hmC at the pregnancy-associated gene clusters in placentas of obese compared to lean mothers. by Kohzoh Mitsuya (4521304)

“…<p>(A) Reciprocal increase in 5mC and decrease in 5hmC at the <i>GH-CSH</i> gene cluster on human chromosome 17q24. …”

cGAS inhibition decreases ISG RNA in H358 cells. by Lorellin A. Durnell-Bettis (22656332)

DBcAMP and glucagon produces a decrease of peripheral insulin sensitivity. by Rita S. Patarrão (737406)

“…DBcAMP: N6,2‟-O-dibutyryladenosine 3‟,5‟-cyclicmonophosphate; cAMP: 3‟,5‟-cyclic adenosine 5‟-monophosphate; GSH:gluthatione.…”

The AMPK inhibitor CC exacerbates palmitate-induced decreases in viability. by Dustin M. Lee (8207457)

PIKfyve inhibition results in decreased melanin accumulation and decreased accumulation of advanced stage melanosomes. by Marc C. Liggins (5018390)

The M650K mutation decreases the firing rate of DRG neurons. by Andreas M. Kist (3106548)

Cellular stress decreases TDP-43 levels in patient neurons with the TDP-43 A90V mutation. by Zhijun Zhang (315079)

Subjects:

EphA4 immunostaining is decreased adjacent to injury site in ephrin-A5-Fc treated mice. by Yona Goldshmit (205708)

“…<p>Immunohistochemical analysis of (A,B) GFAP, (C–F) EphA4 and (G,H) CSPG expression at 2 weeks after spinal cord hemisection and 2 weeks of ephrin-A5-Fc treatment indicated that there was robust GFAP staining in both treated and control mice (A,B). …”