SS1 virus preferentially infects cells with increased Ras/ELK signaling. by Weihong Pan (327613)

“…Controls (uninfected cells) show no bands proving the specificity of antibody for viral proteins. Lower panel shows a significant decrease in the expression of SS1 proteins in infected LnCap cells upon exposure to inhibitors of Ras (FTI-277 at 20 µM), MEK (PD98059 at 25 µM) and ELK (Chromomycin A at 10 µM) but not the vehicle (DMSO). …”

Acetaminophen inhibits mitochondrial respiration of HepG2 cells through complex I. by Sarah Piel (3143667)

“…<p>(a) Representative traces of the Substrate-Uncoupler-Inhibitor-Titration (SUIT) protocol applied to acetaminophen- (10 mM, red trace) or vehicle-treated (control, grey trace) and subsequently permeabilized HepG2 cells. …”

Hypotonic-mediated [Ca²⁺]_i signals require Ca²⁺ influx via TRPC3 in CD cells. by Viktor N. Tomilin (8150094)

“…<p>(<b>A)</b> The average time course of [Ca²⁺]_i changes in response to 10X elevations in perfusion rate from 1.5 ml/min to 15 ml/min (high flow) and application of hypotonic medium (220 mOsm) in the absence and in the presence of a TRPV4 inhibitor, ruthenium red (RuR, 1 μM) in individual CD cells within split-opened area. …”

Table_1_Lacticaseibacillus paracasei LC86 mitigates age-related muscle wasting and cognitive impairment in SAMP8 mice through gut microbiota modulation and the regulation of serum... by Yihui Cai (17420730)

“…Furthermore, there was a significant decrease in serum pro-inflammatory cytokines, such as IL-6, TNF-α, and MCP-1 (p = 0.002, p = 0.000, and p = 0.005, respectively), and an elevation in the anti-inflammatory cytokine IL-10 level (p = 0.000). …”

Corneal Sensitivity and Dry Eye Symptoms in Patients with Keratoconus by Lóránt Dienes (641222)

“…</p><p>Results</p><p>KC patients had significatly decreased tear secretion and significantly higher ocular surface disease index (OSDI) scores compared to controls (5.3±2.2 vs. 13.2±2.0 mm and 26.8±15.8 vs. 8.1±2.3; p<0.001). …”

Presence of iron in polymers extruded with corrosive contaminants or abrasive fillers by Marcos Fernado Franco (6826211)

Diminishing personal information privacy weakens image concerns by Yohanes E. Riyanto (8770784)

DataSheet1_The Effect of Alzheimer’s Disease-Associated Genetic Variants on Longevity.pdf by Niccolò Tesi (11860280)

“…Based on these distributions, we grouped the SNPs in three groups: 17 SNPs increased AD-risk more than they decreased longevity-risk, and were enriched for β-amyloid metabolism and immune signaling; 11 variants reported a larger longevity-effect compared to their AD-effect, were enriched for endocytosis/immune-signaling, and were previously associated with other age-related diseases. …”

DataSheet2_The Effect of Alzheimer’s Disease-Associated Genetic Variants on Longevity.xlsx by Niccolò Tesi (11860280)

“…Based on these distributions, we grouped the SNPs in three groups: 17 SNPs increased AD-risk more than they decreased longevity-risk, and were enriched for β-amyloid metabolism and immune signaling; 11 variants reported a larger longevity-effect compared to their AD-effect, were enriched for endocytosis/immune-signaling, and were previously associated with other age-related diseases. …”

rmMFG-E8 upregulates cyclin D2 and downregulates p53 expression in neural stem cells. by Cletus Cheyuo (703717)

“…(B) rmMFG-E8 downregulates p53 via integrin α_V. Treatment of cultured mouse embryonic neural stem cells with 500 ng/ml rmMFG-E8 significantly decreased p53 gene expression compared with PBS treatment. …”

Effects of full and partial agonists. by Ranjita Dutta-Roy (687241)

“…The relative frequency of the small conductance state (green line) is 0.6 at a ligand concentration of 1 μM and decreases when the ligand concentration is increased, whereas the medium conductance state (blue line) reaches its peak at a concentration above 0.1 μM and most receptors are found in the large conductance state (black line) at 10 μM. …”

Switch to aflibercept in the treatment of neovascular age-related macular degeneration: 30-month results by Elif Ertan (10357215)

Oral Administration of GW788388, an Inhibitor of Transforming Growth Factor Beta Signaling, Prevents Heart Fibrosis in Chagas Disease by Fabiane L. de Oliveira (158730)

“…Interestingly, we further demonstrated that administration of GW788388 at the end of the acute phase (20 dpi) still significantly increased survival and decreased cardiac fibrosis (evaluated by Masson's trichrome staining and collagen type I expression), in a stage when parasite growth is no more central to this event.…”

Sleep spindle results. by Samuel Laventure (2587108)

“…Data deposited in the Dryad repository: <a href="http://dx.doi.org/10.5061/dryad.b4t60" target="_blank">http://dx.doi.org/10.5061/dryad.b4t60</a> [<a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.1002429#pbio.1002429.ref040" target="_blank">40</a>]. * <i>p</i> < 0.05; ** <i>p</i> < 0.01; *** <i>p</i> < 0.001</p>…”

Data Sheet 1_What regulates decomposition in agroecosystems? Insights from reading the tea leaves.pdf by Marshall D. McDaniel (4341325)

N-Terminal end of M₂R-i3 plays important roles in the activation of and co-localization with GIRK channel. by Michihiro Tateyama (5544137)

“…The inhibitory effects of PTX (filled circles) are summarized in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0204447#pone.0204447.t003" target="_blank">Table 3</a>. …”

Summary of the literature. by Narisetti Ashok Kumar (22821918)

MD simulation analysis of the R117P and wild type CYP1B1 structures. by Antara Banerjee (12508)

Seizure spread in the epileptor-network model. by S. Amin Moosavi (13296568)

“…Spread onset times varied across different nodes. Partial spread to a subset of nodes can also occur (see Figs <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0272902#pone.0272902.g002" target="_blank">2</a> and <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0272902#pone.0272902.g008" target="_blank">8</a>). …”

Data_Sheet_1_Plant Evolution History Overwhelms Current Environment Gradients in Affecting Leaf Chlorophyll Across the Tibetan Plateau.docx by Yicheng He (11532058)