Complex I activity is increased in cells with elevated NQO1 levels and is decreased by rotenone. by Jiyeong Kim (433042)

UNC-62 RNAi decreases expression of collagen genes and increases expression of intestinal genes. by Eric L. Van Nostrand (30730)

“…The histogram indicates the distribution of genes by average fold-change upon <i>unc-62</i> RNAi. For 1699 genes with intestine-enriched expression <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003325#pgen.1003325-McGhee1" target="_blank">[23]</a>, <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003325#pgen.1003325-Pauli1" target="_blank">[33]</a>, <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003325#pgen.1003325-Spencer1" target="_blank">[34]</a> as well as the subset of 291 genes that also decrease expression with age <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003325#pgen.1003325-Budovskaya1" target="_blank">[10]</a>, we determined the average mean-centered fold-change from triplicate RNA-seq experiments of <i>unc-62</i> RNAi as compared to controls. …”

Genes whose expression was decreased by 1 mM ouabain by more than 2-fold. by Larisa V. Smolyaninova (3600053)

Insulin ICV injection (14 mU) decreases olfactory detection in fasted rats. by Pascaline Aimé (293920)

“…Before the conditioning, during the last day of habituation (Hab.), both tubes were filled with pure water, and during the first day of aversion acquisition (Av.), both tubes were filled with ISO 10⁻⁵. A repeated measure ANOVA revealed a significant effect of the aversive conditioning (p<0.0001). …”

hESCs-Exo decreased cancer cell proliferation and increased cancer cell death. by Shufeng Zhou (398572)

Bay 61–3606 sensitizes MCF-7 cells to TRAIL by decreasing Mcl-1. by So-Young Kim (562174)

Exposure to low CO₂ levels decreases ER cholesterol levels. by Nityanand Bolshette (17396845)

“…<b>(F)</b> qPCR analysis for cholesterogenic genes from NIH3T3 cells exposed to cholesterol (50 μm) or 25-hydroxycholesterol (10 μm) under 5% or 1% CO₂ for 4 h (mean ± SE, <i>n</i> = 3 biological replicates per condition, ***<i>P</i> < 0.001, nonsignificant (ns), two-way ANOVA with Bonferroni’s multiple comparisons test). …”

Overexpression of mC4 decreased membrane capacitance without altering overall excitability. by Ashley L. Comer (8299128)

Behavioral response to ambiguous conditioned fear cues is decreased in adult neurogenesis-deficient mice. by Lucas R. Glover (3912628)

Expression of neurotrophins and their receptors was decreased in <i>Slitrk6</i>-deficient inner ear. by Kei-ichi Katayama (257931)

“…<p>(A) Real-time PCR analysis of <i>Bdnf</i>, <i>Ntf3</i>, <i>Ntrk2</i>, and <i>Ntrk3</i> in E14.5 inner ear (includes cochlear and vestibular sensory epithelia, and spiral and vestibular ganglia). …”

Nasal mucociliary clearance was decreased in <i>Ttll1</i>^−/− mice. by Toshiyuki Iwata (419270)

“…In the <i>Ttll1</i>^−/− mice, a larger amount of Evans blue persisted in the nasal cavity and a lesser amount was swallowed compared with that in the wild-type (WT) mice (mean ± SEM, n = 5, *P < 0.005 by two-tailed Student's t test).…”

CMV infection decreases integrity of polarized HCoEpiC and increases barrier permeability. by Ekaterina Maidji (3797899)

Characterization of the optimized nanoparticles (These values are means of a minimum of 5 batches). by Anjuman Arora (750291)

rHSP60 decreases viability of B lymphocyte cell line but not macrophage one. by Igor Emiliano L. Souza (18196495)

DHT increases whereas orchidectomy decreases the weight and cross sectional area of hindlimb muscles. by Young-Eun Yoo (323357)

“…<b>A:</b> In WT mice, DHT increased the GN weight by 7% (212.4±8.8 mg), whereas orchidectomy decreased it by 14% (171.4±9.0 mg) compared with control WT mice (198.4±5.5 mg). …”

Aspirin decreases expression of NFκB and β-catenin in colon cancer cells. by Satya Pathi (301408)

“…<p>Decreased p65/p50 in RKO (A) and SW480 (B) cells. Cells were treated for 48 hr with 5 or 10 mM, and whole cell, nuclear and cytosolic extracts were analyzed by western blot analysis as described in the <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0048208#s3" target="_blank">Experimental Procedures</a>. …”

GBE did not modify cell morphology but decreased reactive oxygen species (ROS) levels. by Virginie Rhein (243241)

“…<b>C</b>) Mitochondria-associated ROS levels measured after incubation with DHR (DHR fluorescence units/1×10⁵ cells). ROS levels showed a trend to be increased in APP cells compared to control cells (⁽*⁾p = 0.082, unpaired student's t-test, n = 11, values represent the means ± S.E.). …”

Metabolomic analysis of <i>pgl</i> indicates compensatory changes and decreased pyrimidine metabolism. by Jisun Kim (837555)

Rapamycin decreases Schwann cell markers, whereas statin induces Schwann cell markers. by Andrea Preitschopf (629851)

Global Land Use Change Impacts on Soil Nitrogen Availability and Environmental Losses by Jing Wang (6206297)

“…Anthropogenic activities, particularly land use change and management practices, alter the global nitrogen (N) cycle. As a central part of the global N cycle, soil N supply from net N mineralization (NNM) and net nitrification (NN) contributes to over 50% of crop N uptake. …”