Discovery of 2‑Ethoxy-5-isobutyramido‑<i>N</i>‑1-substituted Benzamide Derivatives as Selective Kv2.1 Inhibitors with In Vivo Neuroprotective Effects by Jie Zhou (28945)

“…In this work, a series of novel benzamide derivatives were designed and synthesized as Kv2.1 inhibitors, and extensive structure–activity relationships led to highly potent and selective Kv2.1 inhibitors having IC₅₀ values of 10^–8 M. …”

Reproduction number <i>R</i>(<i>t</i>) for the duration of the simulation. by Sebastian A. Müller (10688740)

Immunoblotting for insulin sensitivity markers. by Dwight D. Harris (14484648)

Loss of Prox1a decreases PR production at 120 hours post-ablation. by Kellie Veen (17343374)

Scatterplot of fold-change expression for B-cell-specific mRNA transcripts in the whole blood. by Luísa Camacho (5508251)

“…The horizontal gray bars indicate a 2-fold increase and decrease in expression compared to control. …”

Proteins Significantly Decreased only in Metastatic UM Tumors. by John W. Crabb (158933)

“…<p>Average ratio (UM/control), standard error of mean (SEM), and p values (t-test) are shown for proteins significantly decreased only in metastatic tumors in LC MS/MS iTRAQ analyses of 5 metastatic and 5 non-metastatic primary UM tumors.…”

Annual mean energy for the individual wavelet components (thick coloured curves) and a linear model best-fit based on the annual global mean temperature (dashed lines), also estima... by Rasmus E. Benestad (12530330)

Mean Euclidean distances for percentage data (across boroughs and years). by David J. Tonjes (1461925)

<i>Cdkl5</i> -/Y mice show an increased freezing time and a decreased distance traveled during the pretone period in the altered context. by Kosuke Okuda (5150393)

“…There are no significant differences in the freezing time (iii) and distance traveled (iv) in response to the conditioned tone. <i>Cdkl5</i> +/Y, n = 22; <i>Cdkl5</i> -/Y, n = 22. Data indicate means ± SEM.…”

IC₅₀s data of antimalarials against controls. by Winnie Okore (14139712)

Delayed boosting with ALVAC-HIV/AIDSVAX B/E or AIDSVAX B/E increases V1V2-specific IgG concentration and breadth. by LaTonya D. Williams (3140490)

P-values for each factor in the full multiple regression models of volume, cross-sectional area (CSA), width, depth, Euclidean distance from the template (EDT), and phase shift rel... by Drew A. Anderson (14197446)

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Quartile shape signatures of a representative carpal tunnel in neutral posture. by Drew A. Anderson (14197446)

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Minimal dataset. by Drew A. Anderson (14197446)

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Effects of FE and RUD wrist postures on carpal tunnel length. by Drew A. Anderson (14197446)

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Carpal tunnel cross-sections used to calculate morphology metrics. by Drew A. Anderson (14197446)

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Effects of FE and RUD wrist postures on carpal tunnel volume distribution by quartile. by Drew A. Anderson (14197446)

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Increase of proliferating progenitor cells and decrease of terminally differentiated granule neurons in the immature dentate gyrus of <i>PC3/Tis21</i>-null mice at P14. by Stefano Farioli-Vecchioli (256006)

“…<p>(<b>A</b>) The whole population of progenitor cells entering in S-phase, labeled by a short pulse of BrdU (1hour) and by the progenitor cell marker Sox2 (BrdU/Sox2-positive), increased significantly in <i>PC3/Tis21</i>-null mice (1.6-fold). (<b>B</b>, <b>C</b>) The same significant increase is observed for the number of dividing progenitor cells, identified either as (<b>B</b>) Ki67-positive, or as (<b>C</b>) Ki67/Sox2-positive cells (1.5-fold). …”

Non-linear effects of wealth index score on the log-odds of diabetes and hypertension (posterior means with the 97.5% credible interval are shown). by Strong P. Marbaniang (10189860)

The effect of MSC blocker GsMTx-4 on photoresponses from <i>Xenopus</i> rods. by Ulisse Bocchero (9128127)