<i>Ex vivo</i> deletion of <i>sirt1</i> decreases expression of RUNX2 downstream targets. by Kayvan Zainabadi (502381)

“…The homeodomain transcriptional regulators, Msx2, Dlx3, and Dlx5, help establish the early osteoblast transcriptional program, including upregulation of Runx2 expression and activity [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0178520#pone.0178520.ref017" target="_blank">17</a>, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0178520#pone.0178520.ref021" target="_blank">21</a>–<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0178520#pone.0178520.ref024" target="_blank">24</a>]. …”

Increased B-ADAM10 and decreased ADAM17 and TNF in Th2 biased strains. by Lauren Folgosa Cooley (733432)

Spinal cord of CCI-mice treated with EGCG and compound 30 at 14 dpi showed decreased levels of inflammatory cytokines by Xavier Xifró (719821)

Overexpression of cathepsin K in mice decreases collagen deposition and lung resistance in response to bleomycin-induced pulmonary fibrosis-2 by Mrigank Srivastava (94935)

“…(A), data are given as fold change in cathepsin K mRNA of bleomycin-challenged cath K tg mice compared to wild-type mice. …”

ROS levels. by Bo Huang (30906)

“…At 8 h following 2Gy radiation, the ROS level decreased approximately 10% compared to 2 h. Although Sema3a also decreased the ROS level, the differences between the 0ng/ml of Sema3a group and the 50ng/ml Sema3a group were not statistically significant (P>0.05, N = 5).…”

IRE1 depletion decreases heterochromatin, DNA and H3K9me3 methylation, and UHRF1. by Iratxe Zuazo-Gaztelu (21071939)

Metformin decreases CRC-like organoids viability to the same extent as current chemotherapy without significant effects on WT organoids. by Silvia Cruz-Gil (7037249)

<i>L. mexicana</i> promastigote-infected BMDCs have decreased expression of antigen presentation and co-stimulatory molecules. by Irazú Contreras (239776)

Muscle-specific knockdown of <i>nSMase</i> minimally decreases glucosylceramide levels, which are globally elevated in <i>Gba1b</i> mutants. by Kathryn A. Jewett (3756811)

Time adjusted survival curves for high vs. low renalase among patients with COVID-19 disease (using first quartile as cutoff). by Basmah Safdar (12213257)

Cox hazard regression model of renalase and primary composite outcome. by Basmah Safdar (12213257)

Oxidation of glycans results in a decreased production of IL-4 and IL-10 and an increase of IFNγ by parasite specific splenocytes. by Ernesto Rodríguez (840670)

Hdac inhibition with Trichostatin A decreases melanocyte differentiation and prolongs <i>sox10</i> expression in neural crest cells. by Emma R. Greenhill (207837)

TQ decreases CXCR4 expression on MM cells and CXCL12-induced CXCR4/CD45 association. by Gamal Badr (113166)

<i>Myotis rufoniger</i> genome sequence and analyses: <i>M</i>. <i>rufoniger’s</i> genomic feature and the decreasing effective population size of <i>Myotis</i> bats by Youngjune Bhak (3511349)

“…<i>brandtii</i> bat reference genome at a mapping rate of 96.50% covering 95.71% coding sequence region at 10× coverage. …”

Aquaporin 2 Mutations in <i>Trypanosoma brucei gambiense</i> Field Isolates Correlate with Decreased Susceptibility to Pentamidine and Melarsoprol by Fabrice E. Graf (469055)

“…The identified mutant <i>T. b. gambiense</i> are 40- to 50-fold less sensitive to pentamidine and 3- to 5-times less sensitive to melarsoprol than the reference isolates. …”

Akt phosphorylation at both Ser⁴⁷³ and Thr³⁰⁸ was decreased after PTX treatment. by Huawang Sun (655480)

C80A and C247A mutations decrease infectivity. by Shintaro Kobayashi (468967)

Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle by Jinit, Masania

“…We found both young and aged HSA-mUCP1 mice had decreased advanced glycation endproducts (AGEs) formed from MG, lysine-derived Nε(1-carboxyethyl)lysine (CEL) and arginine-derived hydroimidazolone, MG-H1, whereas protein glycation by glucose forming Nε-fructosyl-lysine (FL) was increased ca. 2-fold, compared to wildtype controls. …”
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Phospho-ERK level is decreased in 3D spheroids. by Keven Huang (675616)