A New Rotane Family:  Synthesis, Structure, Conformation, and Dynamics of [3.4]-, [4.4]-, [5.4]-, and [6.4]Rotane¹ by Lutz Fitjer (2466634)

“…All syntheses are based on bicyclobutylidene (<b>9</b>):  [2+1] cycloaddition of cyclobutylidene yields [3.4]rotane (<b>5</b>) (<b>9</b>−<b>5</b>), [2+2] cycloaddition of trimethyleneketene followed by spiroalkylation of the resulting trispiroketone <b>10</b> yields [4.4]rotane (<b>6</b>) (<b>9</b>−<b>10</b>−<b>13</b>−<b>14</b>−<b>6</b>), homologization of <b>10</b> via β-hydroxy selenides gives access to tetraspiroketone <b>11</b> and pentaspiroketone <b>12</b> (<b>10</b>−<b>15</b>−<b>11</b>−<b>16</b>−<b>12</b>), and further elaboration directed toward a cyclopropylcarbene−cyclobutene rearrangement yields [5.4]rotane (<b>7</b>) and [6.4]rotane (<b>8</b>) [<b>11</b>(<b>12</b>)−<b>18</b>(<b>24</b>)−<b>19</b>(<b>25</b>)−<b>20</b>(<b>26</b>)−<b>21</b>(<b>27</b>)−<b>22</b>(<b>28</b>)−<b>23</b>(<b>29</b>)−<b>7</b>(<b>8</b>)]. …”

Presentation_5_Regulatory B Cells Are Decreased and Impaired in Their Function in Peripheral Maternal Blood in Pre-term Birth.PPTX by Mandy Busse (211026)

“…In addition, the percentage of IL-10-producing B cells was decreased in PTB following stimulation with TLR agonists CpG or LPS, alone or combined with CD40L. …”

Top 5 VADER words by TF-IDF before, during, and after Hurricane Dorian for each region. by Krishna Bathina (12883820)

Top 5 VADER words by normalized TF-IDF scores before, during, and after each hurricane. by Krishna Bathina (12883820)

TEM4 depletion decreases TEM4 mRNA and protein levels but no effect on spindle staining by the TEM4 antibody. by Diogjena Katerina Prifti (12988141)

HSP90 inhibition by RGRN-305 and 17-AAG decreased proinflammatory protein secretion. by Hakim Ben Abdallah (14578241)

List of 186 genes that were increased more than 2-fold from control to galactose and decreased more than 1.5-fold from galactose to 2ME2. by Masaru Takashima (13851129)

Dietary zinc repletion decreases Zip10 expression. by Louis A. Lichten (215913)

“…(<b>B</b>) Relative abundance of Zip10 mRNA between ZnA, ZnD, and ZnR groups is shown normalized to 18s rRNA. …”

DGAT-1 Inhibitor A922500 decreases the pro-inflammatory profile and cell death induced by SARS-CoV-2 infection and reduces the viral load in human monocyte. by Suelen Silva Gomes Dias (9928813)

S5 Data - by Christoph Anders (4068499)

Decrease of mitochondrial protein levels in human OPMD muscle biopsies. by Aymeric Chartier (713911)

Decrease of GFP-TbAtg8 fluorescence during starvation. by Remo S. Schmidt (546946)

Mean decrease in accuracy (MDA) of top 15 urine metabolites. by Liam E. Broughton-Neiswanger (8447220)

“…Urine metabolites with a mean decrease in accuracy ≥ 0.004 in at least one post-treatment time point (2–5) were considered for inclusion in the predictive model.…”

Concentration-dependent decrease in treatment efficiency of unmethylated miRNA. by Haiqiu Huang (2036125)

<i>dnak14</i> mutant harbors a transposon insertion in the <i>dnaK</i> coding region and specifies a truncated DnaK protein. by Carissa Chan (18310140)

Performance of selected antimalarials against field isolates during the study period. by Winnie Okore (14139712)

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Association of polymorphic IC_50s versus wild<i>-</i>type at codon 876 in selected drugs tested. by Winnie Okore (14139712)

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Primers used for analysis of four SNPs in one gene. by Winnie Okore (14139712)

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Number of samples per site during the study period. by Winnie Okore (14139712)

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Performance of selected drugs against field isolates during the study period. by Winnie Okore (14139712)

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