Image_3_OCT4 and SOX2 Specific Cytotoxic T Cells Exhibit Not Only Good Efficiency but Also Synergize PD-1 Inhibitor (Nivolumab) in Treating Breast Cancer Stem-Like Cells and Drug-R... by Wei Peng (432211)

“…Besides, PD-1 inhibitor (nivolumab) improved the cytotoxic activity of OCT4&SOX2 CTLs against MCF7-BCSCs in a dose-dependent manner. In vivo, OCT4&SOX2 CTLs plus PD-1 inhibitor (nivolumab) decreased tumor volume and tumor weight while increased tumor apoptosis rate compared to OCT4&SOX2 CTLs alone, PD-1 inhibitor (nivolumab) alone, and control.…”

Telomere length regulates Fst/BMP/pSmad signaling. by Na Liu (102929)

“…<p>(A) Scatter plots showing global differential gene expression profile of WT and G4 <i>Terc</i>^–/–ES cells. …”

Image_1_OCT4 and SOX2 Specific Cytotoxic T Cells Exhibit Not Only Good Efficiency but Also Synergize PD-1 Inhibitor (Nivolumab) in Treating Breast Cancer Stem-Like Cells and Drug-R... by Wei Peng (432211)

“…Besides, PD-1 inhibitor (nivolumab) improved the cytotoxic activity of OCT4&SOX2 CTLs against MCF7-BCSCs in a dose-dependent manner. In vivo, OCT4&SOX2 CTLs plus PD-1 inhibitor (nivolumab) decreased tumor volume and tumor weight while increased tumor apoptosis rate compared to OCT4&SOX2 CTLs alone, PD-1 inhibitor (nivolumab) alone, and control.…”

Data_Sheet_1_Nano- and Macroscale Study of the Lubrication of Titania Using Pure and Diluted Ionic Liquids.pdf by Peter K. Cooper (1345383)

“…The macrotribology measurements demonstrated that friction decreased in P_6,6,6,14 TFSI by four times (μ = 0.13) compared to in hexadecane, even at 60°C and loads up to 10 N. …”

Image_2_OCT4 and SOX2 Specific Cytotoxic T Cells Exhibit Not Only Good Efficiency but Also Synergize PD-1 Inhibitor (Nivolumab) in Treating Breast Cancer Stem-Like Cells and Drug-R... by Wei Peng (432211)

“…Besides, PD-1 inhibitor (nivolumab) improved the cytotoxic activity of OCT4&SOX2 CTLs against MCF7-BCSCs in a dose-dependent manner. In vivo, OCT4&SOX2 CTLs plus PD-1 inhibitor (nivolumab) decreased tumor volume and tumor weight while increased tumor apoptosis rate compared to OCT4&SOX2 CTLs alone, PD-1 inhibitor (nivolumab) alone, and control.…”

Quantitative scoring of collagen II, MMP-13 and ICAM-1 immunohistochemistry. by Julia Lorenz (626379)

Deletion of <i>Foxm1</i> from macrophages increases expression of pro-fibrotic cytokines without affecting number of myeloid cells. by Chinmayee Goda (8694597)

AMOT P130 and PLKHH3 protein expression levels in the study cohort 2. by Yung-Che Chen (381913)

Figure 1; Figure 2; Figure 3; Figure 4; Figure 5; Table 1; Table 2; Table 3; Table 4; SupTable 1; SupTable 2; SupTable 3 by Ramachandran Chelliah (3837415)

Table 1_Uniaxial tensile material properties of adult Chinese dura mater: investigating the influence of age, sex, and anatomical site.docx by Jinming Wang (191356)

“…</p>Results<p>indicated significant age-related degradation: E_C, σ_Tf, ε_Tf; and MaxForce significantly decreased with age (median E_C declined from 28.0 MPa in young adults to 15.3 MPa in the elderly, P < 0.05; median ε_Tf from 0.215 to 0.156, P < 0.05), while E_E showed no significant age correlation (P = 0.10). …”

γδ T cells have similar TCR threshold but enhanced ERK1/2 phosphorylation comparing to αβ T cells. by Hsin-Yuan Cheng (414160)

“…<p>(A) Percentages of BrdU⁺ proliferative cells are higher in the γδ T cell subset <i>in vivo</i>. …”

Phenotypic characterisation of CD4CD25T cells from immunised IFN-γR KO and wild-type DBA/1 mice by Hilde Kelchtermans (12561)

“…</p> CD4CD25T cells isolated from IFN-γR KO and wild-type mice show a similar expression pattern of activation markers, in naive and immunised conditions. …”

Aryl-Fluoride Reductive Elimination from Pd(II):  Feasibility Assessment from Theory and Experiment by Dmitry V. Yandulov (2507068)

“…Three-coordinate T-shaped geometry of Pd^IIAr(F)L (L = NHC, PR₃) was shown to offer kinetics and thermodynamics of Ar−F elimination largely compatible with synthetic applications, whereas coordination of strong fourth ligands to Pd or association of hydrogen bond donors with F each caused pronounced stabilization of Pd(II) reactant and increased activation barrier beyond the practical range. Decreasing donor ability of L promotes elimination kinetics via increasing driving force and <i>para</i>-substituents on Ar exert a sizable S_NAr-type TS effect. …”

IKKε interacts with PML and disrupts the PML nuclear bodies. by Xiaoqian Wang (460263)

“…<p>(<i>A</i>) IKKε interacts with PML. HEK293T cells were co-transfected with indicated plasmids and cell lysates were subjected to IP and IB with indicated antibodies. …”

Introduction of <i>yata</i> mutations into the <i>Drosophila</i> Alzheimer's disease model and partial rescue of the lethality by <i>yata</i> knockdown. by Koto Furotani (5759351)

“…Expression of <i>yata</i> was decreased by knockdown. **: p<0.01 (t-test). N = 5. …”

Inhibition of tumorgeneic activity in Oct-4 siRNA-treated LC-CD133⁺ with chemoradiotherapy. by Yu-Chih Chen (151468)

“…(A) The tumor volume and (B) The number of pulmonary tumor nodules were significantly decreased in Oct-4 siRNA-treated LC-CD133⁺ when exposed to IR alone, cisplatin alone, or IR combined with cisplatin. …”

DataSheet_1_Etiologic characteristics revealed by mNGS-mediated ultra-early and early microbiological identification in airway secretions from lung transplant recipients.xlsx by Xiaoqin Zhang (517854)

“…Within one month, 26 (68.42%) recipients got infected (with a median time of 9 days), among which 10 (38.46%) cases were infected within one week. …”

Table 1_Global, regional, and national trends in DALYs for blindness and vision loss in teenagers and young adults, 1990–2019: an age-period-cohort analysis based on the Global Bur... by Juan Lu (275293)

“…As reflected by local drift, the DALYs had decreasing trends across all age groups, except in high SDI countries. …”

image_2_Type I and III Interferon Productions Are Impaired in X-Linked Agammaglobulinemia Patients Toward Poliovirus but Not Influenza Virus.jpeg by Anderson Dik Wai Luk (5618996)

<i>Otx2</i> requires <i>Lmx1b</i> for the development of mdDA neurons. by Orna Sherf (804524)