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CsA reduces Flk1 protein expression and significantly decreases the percentages of Flk1+ cells.
Published 2015“…Scale bars = 100 μm. (C) Representative flow cytometry profiles showing the decreased percentages of Flk1+ cells in P19 cells treated with 0.32 μM CsA during EB formation for 48 and 96 h, respectively. …”
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GBE decreased secretion of Aβ1-40 in APP cells.
Published 2010“…Secreted Aβ1-40 was significantly decreased in GBE-treated APP cells (100 µg/ml; 24 h). …”
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(R)-albuterol decreases cytokine protein levels in activated T cells
Published 2011“…</p><p></p> (R)-albuterol, (S)-albuterol or racemic albuterol (R + S) at a dose (10M) were added to T (EL-4) cells pre-activated with mitogens Concanavalin A (Con A, 5 μg/ml) and phorbol myristate acetate (PMA, 100 ng/ml) (CP). …”
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Genes whose expression was decreased in RASMC subjected to Na<sup>+</sup>,K<sup>+</sup>-ATPase inhibition.
Published 2014“…Given <i>in italics</i> are genes whose differential expression was detected in ischemic tissue by whole genome microarray-based analysis <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0110597#pone.0110597-Mazzatti1" target="_blank">[12]</a>–<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0110597#pone.0110597-Leonard1" target="_blank">[18]</a>. …”
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Dexamethasone decreases PGC-1α protein expression and transcription.
Published 2016“…<p>(A) Treatment of L6 myotubes with Dex (100nM, 48hrs) decreased PGC-1α protein expression (p = 0.01). n = 3/treatment from 3 experiments. …”
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Dexamethasone decreases CRTC1 and CRTC2 nuclear localization.
Published 2016“…<p>Treatment of L6 myotubes with Dex (100nM, 48hrs) decreased (A) total CRTC1 (p = 0.004 and CRTC2 protein (p = 0.0007). n = 9/treatment from 3 experiments. …”
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TUDCA decreases ER stress in HOX neonatal rat lungs.
Published 2022“…<p>(<b>A</b>) The expression levels of ER stress markers (P-PERK 0.6±0.1-fold, p<0.001, n = 5; PERK 0.7±0.1-fold, p = 0.00364, n = 5; P-IRE1α 0.6±0.0-fold, p<0.001, n = 5; IRE1α 0.6±0.1-fold, p<0.001, n = 5; GRP78 0.8±0.1-fold, p<0.001, n = 5; cleaved ATF6 0.1±0.0-fold, p<0.001, n = 5; spliced XBP1 0.3±0.0-fold, p<0.001, n = 5; 2 males and 3 females) are all decreased while the N-glycosylated VEGFR2 is increased (3.5±0.2-fold, p<0.001, n = 5) in HOX neonatal lungs at P10 indicating TUDCA can attenuate hyperoxia-induced ER stress. …”
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Adding tsetse control to medical activities contributes to decreasing transmission of sleeping sickness in the Mandoul focus (Chad)
Published 2017“…Pre-2014, control of HAT relied solely on case detection and treatment, which lead to a gradual decrease in the number of cases of HAT due to annual screening of the population.…”