Validation of primary screen hits reveals compounds that recapitulate increased spheroid size (swell) or decreased MUC5AC in the lumen. by Pranjali Beri (14945400)

“…Compounds that appeared to cause toxicity were identified by observing a significant decrease in spheroid counts in the swell readout or a significant decrease in the total nuclear intensity of the MUC5AC ratio readout. …”

S100 Calcium-Binding Protein A6 Promotes Epithelial-Mesenchymal Transition through β-Catenin in Pancreatic Cancer Cell Line by Xue Chen (127892)

“…Specifically, expression of E-cadherin was increased, whereas expression of N-cadherin and vimentin was decreased. Finally, we demonstrated that S100A6 alters the expression of EMT-related markers via β-catenin activation. …”

Immunohistochemistry of Ki67, PCNA, and α-SMA was performed on the VX2 tumor rabbit model at days 1, 2, 5 and 7 after nsPEF ablation. by Qing-Gang Li (273341)

A photomicrograph of sections of the ovary in different groups [Masson’s trichrome x100]. by Rasha Atta (21608582)

Phosphorylation of secondary-signaling molecules were regulated by metformin treatment in mHypoE-46 neurons. by Wenqing Ye (3015147)

“…Levels of phospho-proteins were normalized to β-actin and expressed as mean ± SEM. Representative blots for phospho-proteins and β-actin are depicted beneath each graph. 20 μM metformin increased phosphorylation of AMPK (A) and S6K (B) at 10 min (<i>*p<0</i>.…”

Cancer cells internalized efficiently hESCs-Exo. by Shufeng Zhou (398572)

Effects of nuclear hormone treatments on <i>kcnk5b</i>, <i>rcan2</i>, and control genes in pectoral fin buds and adult fins and sufficiency/necessity experiments for <i>rcan2</i>. by Xiaowen Jiang (8291814)

Replacement of intra- and extracellular chloride for D-gluconate eliminated statistically significant decreases in GLT-1 stoichiometric current and the current/flux ratio in 100–30... by Anatoli Y. Kabakov (729047)

Nicotine decreased Akt phosphorylation in SK-BR-3 cells. by Masanori A. Murayama (5774585)

Participant Recruitment Flowchart. by Sandra M. Ragheb (12975445)

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Characteristics of Participants (n = 65). by Sandra M. Ragheb (12975445)

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Patient Engagement Panel Key Messages. by Sandra M. Ragheb (12975445)

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Screenshots of the mHealth Platform. by Sandra M. Ragheb (12975445)

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Association Between App Feasibility and Quality of Life and 30-Day Hospital Readmission. by Sandra M. Ragheb (12975445)

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Post-Discharge MHealth Participant Satisfaction Responses by Age Category. Categorical variables expressed as n (%). Percentages include participants who Agreed or Strongly Agreed... by Sandra M. Ragheb (12975445)

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S5 Data - by Renjie Wang (1986553)

“…PI_ABS, W_K, V_J, and ΔI/I₀ decreased over time, while Rubisco enzyme activity decreased, while proline (Pro) levels increased. …”

MVEC viability is decreased over time in PEG-based hydrogels. by Rebecca A. Scott (488956)

Depletion of SAMHD1 induces cell cycle delay and spontaneous DNA damage response. by Kiwon Park (6492266)

FLIM-FRET measurements with KIRIN1 sensor detects relative changes in intracellular K⁺. by Xiaowen Jiang (8291814)

“…<b>(Ab)</b> FLIM-FRET measurements of the KIRIN1 sensor expressed in the same cells that were patched in Aa detected decreases in intracellular K⁺ in cells expressing CMV:<i>kcnk5b</i>-mCherry (blue) compared to cells lacking the expression of the channel (CMV:mCherry, red). …”

Risk assessment for hospital admission in patients with COPD; a multi-centre UK prospective observational study by Jilles M. Fermont (3746068)

“…In total, 291 of 714 individuals experienced 762 hospitalised AECOPD during five-year follow up. Poorer performance of SPPB was associated with both higher rate (IRR 1.08 per 1 point decrease, 95% CI 1.01 to 1.14) and increased length of stay (IRR 1.18 per 1 point decrease, 95% CI 1.10 to 1.27) for hospitalised AECOPD. …”