Generation of transcriptome datasets. by Paul Montague (285622)

“…The resultant transcriptome database (<a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0009892#pntd.0009892.s007" target="_blank">S2 Table</a>) set out for each pairing in order of decreasing p values and corresponding fold changes.</p> <p>(XLSX)</p>…”

G4-DNA Formation in the <em>HRAS</em> Promoter and Rational Design of Decoy Oligonucleotides for Cancer Therapy by Alexandro Membrino (206370)

“…When we introduced in sequence <em>hras</em>-1 or <em>hras</em>-2 two point mutations that block quadruplex formation, transcription increased 5-fold, but when we stabilized the G-quadruplexes by guanidinium phthalocyanines, transcription decreased to 20% of control. …”

Deterministic sensitivity analysis. by Katharina Wahedi (7136459)

“…Bars on the right indicate an increase of ICER, bars on the left show a decrease of ICER. Changes resulting from increasing the parameters are represented by green bars while those resulting from a decrease of parameters are shown in red.…”

Resveratrol Protects Chondrocytes from Apoptosis via Altering the Ultrastructural and Biomechanical Properties: An AFM Study by Hua Jin (320594)

“…CCK-8 assay showed that 100 μM RV significantly prevented SNP-induced cytotoxicity. …”

Infiltration of blood clots by cancer cells. by Stephanie Rossnagl (553093)

“…(F) Evaluation of cancer cell numbers when injected 5 minutes after clot induction showed a significant decrease in the number of cancer cells detected in the bone marrow at 1 hour after clot induction (p<0.05) but not at later time points (4, 24 and 48 hours after clot induction) (p = ns). n = 4–8 per time point.…”

Characterization of LNCaP cell growth cultured within biomimetic hydrogels in normal growth media, RPMI and 10% FBS. by Shirly Sieh (139080)

“…<p>(A) Growth curves of LNCaP cells over 7 days for 2D cultures (left) and 28 days for 3D cultures (right) in normal growth media measured by total DNA content (mean ± SE). …”

Selectivity of PRMT5 inhibition with C220. by Shelby L. Sloan (10803222)

“…For all cell lines, effects of PRMT5 inhibition with C220 treatment on biomarkers of PRMT5 activity shows a dose-dependent decrease in global marks of symmetric di-methylarginine (SDMA) and symmetric di-methylation of histone H4 arginine-3 (H4R3me2s) with a minimal effect to PRMT5 or global asymmetric di-methylarginine (ADMA). …”

ScFv 2LF dissociation rate constants with each LF variant, measured by Biacore experiments. by Philippe Thullier (320909)

“…<p>The five residues whose mutation to alanine resulted in a 3-fold, or larger, decrease of the dissociation constant are shown in bold.…”

The Cellular Interplay Between Na+/H+ Exchanger Isoform I and Osteopontin in Cardiac Hypertrophy by Abdelaziz, Iman Ahmed

“…This was significantly abolished in the presence of siRNA-OPN (20.2 fold decrease±0.12 of control) and (68.5±0.24% vs. 586.5±103.54% NHE1-infected). …”
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Mutation analysis of GATA and ETS sites in the −252/+38 region of the promoter. by Alexandra Le Bras (243728)

“…<p><b>A</b>. Right; H5V endothelial cells (black bars) and L929 fibroblasts (white bars) were transfected with 80 fmoles of pGL3basic (Ctrl), −8409/+38Luc or a −8409/+38Luc mutant where the GATA (GATAmt) site had been mutated, and with 54 fmoles pCH110 normalization vector. …”

Image_8_Preservation of exopolymeric substances in estuarine sediments.JPEG by Thibault Duteil (13264521)

“…Our results showed a predictable decrease in EPS concentrations (proteins and polysaccharides) and reactivity from the surface biofilm to a depth of 0.5 m, possibly linked to heterotrophic degradation. …”

Image_3_Preservation of exopolymeric substances in estuarine sediments.JPEG by Thibault Duteil (13264521)

“…Our results showed a predictable decrease in EPS concentrations (proteins and polysaccharides) and reactivity from the surface biofilm to a depth of 0.5 m, possibly linked to heterotrophic degradation. …”

Image_2_Preservation of exopolymeric substances in estuarine sediments.JPEG by Thibault Duteil (13264521)

“…Our results showed a predictable decrease in EPS concentrations (proteins and polysaccharides) and reactivity from the surface biofilm to a depth of 0.5 m, possibly linked to heterotrophic degradation. …”

Image_4_Preservation of exopolymeric substances in estuarine sediments.JPEG by Thibault Duteil (13264521)

“…Our results showed a predictable decrease in EPS concentrations (proteins and polysaccharides) and reactivity from the surface biofilm to a depth of 0.5 m, possibly linked to heterotrophic degradation. …”

Image_6_Preservation of exopolymeric substances in estuarine sediments.JPEG by Thibault Duteil (13264521)

“…Our results showed a predictable decrease in EPS concentrations (proteins and polysaccharides) and reactivity from the surface biofilm to a depth of 0.5 m, possibly linked to heterotrophic degradation. …”

Image_7_Preservation of exopolymeric substances in estuarine sediments.JPEG by Thibault Duteil (13264521)

“…Our results showed a predictable decrease in EPS concentrations (proteins and polysaccharides) and reactivity from the surface biofilm to a depth of 0.5 m, possibly linked to heterotrophic degradation. …”

Image_9_Preservation of exopolymeric substances in estuarine sediments.JPEG by Thibault Duteil (13264521)

“…Our results showed a predictable decrease in EPS concentrations (proteins and polysaccharides) and reactivity from the surface biofilm to a depth of 0.5 m, possibly linked to heterotrophic degradation. …”

Image_1_Preservation of exopolymeric substances in estuarine sediments.JPEG by Thibault Duteil (13264521)

“…Our results showed a predictable decrease in EPS concentrations (proteins and polysaccharides) and reactivity from the surface biofilm to a depth of 0.5 m, possibly linked to heterotrophic degradation. …”

Quantifying the Human Cost of Global Warming (Data) by Timothy M. Lenton (15312245)

“…Reducing global warming from 2.7 to 1.5 °C results in a ~5-fold decrease in the population exposed to unprecedented heat (MAT ≥29 °C). …”

Quantifying the Human Cost of Global Warming (Code) by Timothy M. Lenton (15312245)

“…Reducing global warming from 2.7 to 1.5 °C results in a ~5-fold decrease in the population exposed to unprecedented heat (MAT ≥29 °C). …”