Evaluation of MGMT inhibitors with chemosensor 1. by Andrew A. Beharry (1940068)

“…Data were normalized to measurements without inhibitor. Each data point is the average of 3 measurements.</p>…”

Relation of population spike recovery with apoptosis rates. by Antonio H. Martins (184248)

“…For the NMDA lane, the perfusion with ACSF continued for 1 h. Then 0.5 mM NMDA was applied for 10 min; the second lane was superfused with 5 µM of the caspase 9 inhibitor for 1 h after NMDA washout; the third lane was superfused with the inhibitor for 1 h prior to exposure to 0.5 mM NMDA for 10 min. …”

Hit expansion around chloroxine. by Sam Barker (4832121)

“…This modification causes a significant decrease in this compound’s activity as a co-treatment with ceftazidime, with a <i>p</i>IC50 ≈ 3.4. 5,7-dichloro-2-methyl-8-quinolinol differs from chloroxine by addition of a methyl group in the 2-position (B). …”

Summary of the in vitro and in vivo characterization of PCNA mutants. by Yearit Fridman (240019)

“…</p>c<p>Fold increase or decrease in the PCNA-partner interaction affinities measured as the generation time of the Y2H strains grown in liquid selective media lacking histidine, relative to cells expressing WT PCNA (see <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.1000507#pbio.1000507.s004" target="_blank">Figures S4</a> and <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.1000507#s4" target="_blank">Materials and Methods</a>).…”

Table_1_Effect of Ultraviolet-C Light-Emitting Diode Treatment on Disinfection of Norovirus in Processing Water for Reuse of Brine Water.DOCX by So-Ra Yoon (4600960)

“…Moreover, the k_inact increased 1.69-fold with a 56-NTU sample (the highest turbidity studied) when the impeller system was set at 100 rpm. …”

Data Sheet 1_Assessment of heat-killed E. coli expressing Chikungunya virus E2 protein as a candidate vaccine for dual protection against Chikungunya virus and E. coli.docx by Surajit Patra (18400578)

“…The CHIKV neutralization assay results showed a two-fold decrease in CHIKV TCID50 value after 12 hours and a three-fold reduction after 120 hours. …”

mEGFPpH detects intracellular pH changes induced by glutamate transport. by Spencer D. Watts (327115)

“…<b>F)</b> Representation of the magnitude of the slope of mEGFPpH fluorescence ratio decrease (left y-axis) as a function of the applied glutamate concentration compared with the glutamate transport activity (right y-axis) in similarly transfected cells.…”

Blockade of GKAP degradation prevents Aβ-induced actin cytoskeleton remodeling. by Francesco Roselli (211670)

“…Upon Aβ treatment, GKAP-WT cluster size decreased to 64.4±11.5% (p<0.05) of vehicle-treated control. …”

Alpha activity induced by novel stimuli during wakefulness. by Perrine Ruby (486674)

“…Black dots on the topographies indicate electrodes showing a significant alpha increase or decrease compared to baseline. …”

Dataset for Mathematical Model of in vitro Hepatocellular Cholesterol and Lipoprotein Metabolism, fig. 6 by Yuri Efremov (8450409)

LncRNAs are expressed in leukocytes and exhibit differential expression in PD and following DBS. by Lilach Soreq (89966)

“…(B) Differential expression analysis of the detected lncRNAs using common dispersion model and trimmed normalization identified 13 lncRNAs as highly significantly changes (FDR<0.05) in PD patients leukocytes pre-DBS as compared with HC, 8 exhibiting increase and 5 – decrease in PD (C) Differential expression analysis of the post-DBS leukocyte samples compared to the pre-DBS state of the same patients leukocytes detected 18 DBS-modified lncRNAs (4 up- and 14 down-regulated), four of which also changed in the disease pre- treatment (color marked). …”

Revealing Cooperation between Knotted Conformation and Dimerization in Protein Stabilization by Molecular Dynamics Simulations by Yan Xu (14594)

“…The topological knot is thought to play a stabilizing role in maintaining the global fold and nature of proteins with the underlying mechanism yet to be elucidated. …”

Revealing Cooperation between Knotted Conformation and Dimerization in Protein Stabilization by Molecular Dynamics Simulations by Yan Xu (14594)

“…The topological knot is thought to play a stabilizing role in maintaining the global fold and nature of proteins with the underlying mechanism yet to be elucidated. …”

SLS-4 is required for the <i>in vitro</i> ubiquitination of poly-SUMO-2 chains and degradation of SUMO conjugates <i>in vivo</i>. by Chris Boutell (205885)

“…(B) Quantification of Poly-Ub-S2ⁿ species (dotted line) detected by western blot analysis in reaction mixtures containing ICP0, ICP01-396, and ICP01-396mSLS-4 expressed as a relative fold decrease in relation to reaction mixtures containing wt ICP0. …”

CTR-C PDZ- binding motif mutation and TJ disruption and invasion. by Ahmed Aljameeli (2548528)

“…Again, the knock-down of CTR produced a significant decrease in PCP of PC-3M cells, demonstrating the importance of endogenous CTR in regulating TJ stability of PC-3M cells. …”

Fig 5 - by Alexander M. Dreyer (11785896)

“…Colored sensors denote significant changes (blue = decrease, red = increase) lasting for at least 100 ms in the 2 s windows of interest. …”

Inhaled fluticasone propionate impairs GATA-3 nuclear localization in PBMCs. by Kittipong Maneechotesuwan (372725)

“…(C) Immunoblotting analyses of PBMCs demonstrated a time-dependent decrease in nuclear expression of GATA-3, and increased cytoplasmic GATA-3 expression after inhalation of FP. …”

Sexual dimorphism in <i>Drosophila</i> triglyceride storage and breakdown. by Lianna W. Wat (8339454)

“…In 5-day-old <i>w</i>^<i>1118</i> virgin males, we observed a significant decrease in triglyceride levels between 0 and 12 hours STV and a further decrease between 12 and 24 hours STV (<i>p</i> = 3.0 × 10⁻⁵, 0.0, respectively; one-way ANOVA followed by Tukey HSD test). …”

Stem peptides interact with the dengue virus membrane. by Aaron G. Schmidt (173976)

“…<p>Decrease in pyrene-excimer fluorescence intensity, as a function of the concentration of stem peptide added to pyrene-labeled virions, normalized to its complete loss upon addition of TX100.…”

<i>CasBurs α</i> and <i>ß</i> expressions in TGCs and CasBurs, CCAP and CHH protein contents in TGCs, POs and hemolymph during the molt cycle. by J. Sook Chung (130997)

“…Note the significant increase in TGC-contents and dramatic decrease in PO-contents during postmolt stage A_{2 hr}. …”