TRα2 shows dominant negative activity on positively and negatively regulated T₃ target genes <i>in vivo</i>. by Hajer Guissouma (586934)

“…</b><i>ME-tk-luc</i> transcription was measured in hypothyroid (PTU) 2 days old mice treated with T₃ (2.5 µg/g b.w.) (PTU+T3) or saline (PTU), 18 h after hypothalamic injection of 1 µg reporter construct and 100 ng expression vector (empty pSG5 (Ct) or pSG5-TRα1 (TRα1) or pSG5-TRα2 (TRα2)). …”

HCG phosphorylated ERK1/2. by Zongwen Li (284112)

“…Thus, here we treated non-transfected DU145 cells with different doses of 0, 25, 50, 100, and 200 ng/ml hCGβ for 1 h. Western blot showed that hCGβ standards phosphorylated ERK1/2 in a dose-dependent trend. …”

Association between Insulin and Nitric Oxide in Human Retinal Microvascular Endothelial Cells in vitro by Rizk, Nasser Moustafa

“…This study demonstrated that hyperglycemia causes an increase in ROS/oxidative stress and apoptosis, while insulin promotes a significant decrease in ROS and apoptosis. eNOS mediated NO production increases with hyperglycemia but remarkably decreases with insulin treatment after 1 hour, 2 hours and 4 hours. …”
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Relation between different CTL mechanisms, non-CTL inhibition and HT during infection clearance. by Ashish Goyal (644290)

“…The T cell clearance number (<i>n</i>_<i>CTL</i>) is shown as brown text at each data point under the different mechanisms of cytolytic killing, (A) Mechanism 1 (M1), (B) Mechanism 2 (M2), (C) Mechanism 3 (M3), and (D) Mechanism 4 (M4). …”

Neuropathy-related mutations alter the membrane binding properties of the human myelin protein P0 cytoplasmic tail by Arne Raasakka (180418)

Effects of malaria on the proteome in mammary gland tissue of pregnant mice. by Mamoru Niikura (4103791)

“…<p>(A and B) Venn diagram of protein levels in mammary gland tissue of uninfected and infected pregnant mice that changed 0.5-fold (A) or 2-fold (B) compared with uninfected virgin mice. …”

File S1 - Optogenetic Measurement of Presynaptic Calcium Transients Using Conditional Genetically Encoded Calcium Indicator Expression in Dopaminergic Neurons by Carmelo Sgobio (652457)

“…(E) Comparison of different inter-stimulus interval (ISI) effects on stability of PreCaTs. Stimulation with 5-min and 3-min ISIs revealed a minor (7–15%) decrease in current amplitude that overlapped with that observed during to our standard 30-sec ISI condition (10–20% decrease). …”

<i>FANCF</i> shRNA inhibits cell proliferation, increases apoptosis in T-47D and MCF-7 cells. by Yanlin Li (309835)

“…(B) Quantitative analysis of the fold decrease of total cell number in MCF-7 cells and T-47D cells treated with <i>FANCF</i> shRNA compared with control shRNA. …”

Table_1_Dual RNA-seq in filarial nematodes and Wolbachia endosymbionts using RNase H based ribosomal RNA depletion.XLSX by Lindsey J. Cantin (18582037)

“…The custom nematode depletion library had the lowest percentage of ribosomal reads across all methods, with a 300-fold decrease in rRNA when compared to the total RNA library. …”

Venn diagram representing the RNA sequencing results. by Shyamasree De Majumdar (168216)

“…The arrows ⬇ indicates a lower than 0.5 fold decrease in transcription compared to calibrator; ⬆ indicates a higher than 2 fold transcription compared to calibrator. …”

Phosphate Binding with Sevelamer Preserves Mechanical Competence of Bone Despite Acidosis in Advanced Experimental Renal Insufficiency by Jarkko Jokihaara (94570)

“…Final plasma phosphate increased 2.4- to 2.9-fold, and parathyroid hormone 13- to 21-fold in CRI rats, with no difference between sevelamer-treated and untreated animals. …”

Enterohemorrhagic <em>Escherichia coli</em> O157∶H7 Gene Expression Profiling in Response to Growth in the Presence of Host Epithelia by Narveen Jandu (265979)

“…Relative to bacteria grown in each of the other conditions, EHEC O157∶H7 cultured in the presence of cultured epithelial cells displayed a distinct gene-expression profile. A 2.0-fold increase in the expression of 71 genes and a 2.0-fold decrease in expression of 60 other genes were identified in EHEC O157∶H7 grown in the presence of epithelial cells, compared to bacteria grown in media alone.…”

Presentation_1_Dual RNA-seq in filarial nematodes and Wolbachia endosymbionts using RNase H based ribosomal RNA depletion.PPTX by Lindsey J. Cantin (18582037)

“…The custom nematode depletion library had the lowest percentage of ribosomal reads across all methods, with a 300-fold decrease in rRNA when compared to the total RNA library. …”

Circulating microRNA and automated motion analysis as novel methods of assessing chemotherapy-induced peripheral neuropathy in mice by Qinghai Peng (6260816)

“…Among the three miRNAs analyzed, only miR-124 was statistically significantly increased (5 fold and 10 fold on day 8 and day 16, respectively). …”

Circle-specific PCR and relative RNase R resistance. by Peter L. Wang (204516)

“…All linear isoforms were sensitive to RNase R, showing a greater than 32-fold drop in abundance after RNase R treatment (ΔCt <−5). …”

Table_2_Dual RNA-seq in filarial nematodes and Wolbachia endosymbionts using RNase H based ribosomal RNA depletion.XLSX by Lindsey J. Cantin (18582037)

“…The custom nematode depletion library had the lowest percentage of ribosomal reads across all methods, with a 300-fold decrease in rRNA when compared to the total RNA library. …”

Marimastat reversed hepatic steatosis in diet-induced obese mice as well as in <i>ob/ob</i> animals, as demonstrated by histology and magnetic resonance spectroscopy. by Vincent E. de Meijer (343377)

“…Histological findings were confirmed with MRS, demonstrating a decrease in fat content in Marimastat-treated animals (A,B bottom panels).…”

Anti-obesity effects of <i>Spirulina platensis</i> protein hydrolysate by modulating brain-liver axis in high-fat diet fed mice by Bingli Zhao (6862250)

“…The most markedly changed genes included: Acadm (-34.7 fold), Gcg (2.5 fold), Adra2b (2 fold) and Ghsr (2 fold) in brain; Retn (39 fold), Fabp4 (15.5 fold), Ppard (6 fold) and Slc27a1 (5.4 fold) in liver. …”

Mannitol uptake is repressed in vitro, but mannitol reaches <i>S</i>Tm inside host cells without affecting the host or bacterial metabolism. by Karin Mitosch (16851651)

“…Dashed lines show a 2-fold increase/decrease. (H) Fold change in CFUs of <i>S</i>Tm in the <i>glpD</i> mutant compared to the wt at 12 hpi in RAW264.7 cells with or without the addition of mtl or glyc. …”

<i>Smad6</i> repression in senescence. by Atsushi Kaneda (198186)

“…Numbers under bands of phosphorylated Smad1/5/8 and pan-Smad1 showed densities relative to the band for RasV12 cells (<i>left panel</i>), and the ratio of densities for phosphorylated Smad1/5/8 to pan-Smad1 was decreased to 0.25-fold in <i>Smad6</i>-introduced RasV12 cells (<i>right panel</i>). …”