Genus and phylum composition of the feline faecal microbiome. by Oliver Deusch (497048)

“…The central circular plot illustrates the community structure at the phylum level (five most abundant phyla shown) allowing for quick inference of phylum level composition at a given age as well as temporal distribution of a phylum. …”

Differential OTU abundance of anode-attached microbes and reactor microbes between M1L and M2H reactors. by Nattawet Sriwichai (18847466)

“…<p><b>A</b>, Volcano plot demonstrating significantly different OTUs between M1L and M2H using the criteria: a log-transformed FDR < 0.05 and an absolute log₂ fold-change ≥ 5. 74 OTUs are downregulated while 43 OTUs are upregulated in M1L/M2H. …”

Supplementary Material for: High-Throughput Data of Circular RNA Profiles in Human Temporal Cortex Tissue Reveals Novel Insights into Temporal Lobe Epilepsy by Li J. (2831522)

“…Bioinformatic analysis revealed that circ-EFCAB2 binds to miR-485-5p to increase the expression level of the ion channel CLCN6, while circ-DROSHA interacts with miR-1252-5p to decrease the expression level of ATP1A2. …”

DataSheet_1_Glutaredoxin 2 Reduces Asthma-Like Acute Airway Inflammation in Mice.pdf by Eva-Maria Hanschmann (740672)

“…The Grx2 Cys-X-X-Ser mutant that facilitates de-/glutathionylation, but does not catalyze dithiol/disulfide exchange lost the ability to protect from airway hyper reactivity and to decrease NO release by macrophages, however, it reduced the number of infiltrating immune cells and IL-5 release. …”

Serology for Trachoma Surveillance after Cessation of Mass Drug Administration by Diana L. Martin (300642)

“…Among 1–9 year olds, TF prevalence was 6.5%, whereas only 3.5% were seropositive. Force of infection modelling indicated a 10-fold decrease in seroconversion rate at a time corresponding to MDA commencement. …”

AmB-resistant strains critically depend on high levels of Hsp90 function for survival. by Benjamin Matteson Vincent (477570)

“…<p>(A) Mild inhibition of Hsp90 not only reverses AmB resistance but selectively kills AmB-resistant isolates. Spot assays (5-fold serial dilutions) of wild-type (SC5314), fluconazole-resistant (Isolate #2, <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.1001692#pbio.1001692-White2" target="_blank">[61]</a>), and AmB-resistant (ATCC 200955) <i>C. albicans</i> on RPMI media containing antifungals and/or Hsp90 inhibitors at the indicated concentrations. …”

Portrait of Ependymoma Recurrence in Children: Biomarkers of Tumor Progression Identified by Dual-Color Microarray-Based Gene Expression Analysis by Matthieu Peyre (241074)

“…Conversely, ASPM expression was more frequently positive at relapse (87.5% vs 37.5%, p = 0.03). Loss or deletion of the MT genes cluster was never observed at relapse. …”

Excess mortality and hospitalizations in transitional-age youths with a long-term disease: A national population-based cohort study by Antoine Rachas (197007)

“…Their mortality rate between the ages of 14 and 21 years was 20.9/10,000 person-years (13.7–32.1) <i>versus</i> 1.9 (1.5–2.5) for adolescents without a LTD. Mortality was higher in males than females in youths without a LTD, but not in those with a LTD. …”

RAD21 is necessary for ERα binding within the <i>MYC</i> locus but not an exogenous ERE. A) RAD21 silencing abrogates ERα binding upstream of <i>MYC</i>. by Miranda V. McEwan (121381)

“…MCF7 cells were transfected for 48 hours with Control, RAD21 or ESR1 siRNA and either a negative control (NEG) plasmid, a positive control plasmid (POS) or a plasmid encoding the firefly luciferase reporter gene under the control of 5 EREs. Cells were treated with vehicle (V) or estradiol (E) for 24 hours before luciferase activity was measured. …”

A robust intracellular metabolite extraction protocol for human neutrophil metabolic profiling by Susama Chokesuwattanaskul (5813888)

“…Cell number and number of scans (NS) were optimised as >3.6 million cells and 512 NS. 327 spectral bins were defined in the neutrophil spectra, of which 287 (87.7%) were assigned to 110 metabolites that included: amino acids, peptides and analogues; carbohydrates, carbonyls and alcohols; nucleotides, nucleosides and analogues; lipids and lipid-like molecules; benzenoids; and other organic compounds. 43 metabolites changed at least 1.5 fold (increase or decrease) after the addition of PMA for 5 or 15 min. …”

2′-<em>O</em> Methylation of the Viral mRNA Cap by West Nile Virus Evades Ifit1-Dependent and -Independent Mechanisms of Host Restriction In Vivo by Kristy J. Szretter (165885)

“…In comparison, WNV-E218A was virulent after intracranial infection as judged by increased infection in different regions of the central nervous system (CNS) and a greater than 16,000-fold decrease in LD₅₀ values in <em>Ifit1</em>^−/− compared to wild type mice. …”

Assessing Mitochondrial DNA Variation and Copy Number in Lymphocytes of ~2,000 Sardinians Using Tailored Sequencing Analysis Tools by Jun Ding (80820)

“…Both homoplasmies and heteroplasmies show 5-fold higher transition/transversion ratios than variants in nuclear DNA. …”

Image_1_Increased miR-142-3p Expression Might Explain Reduced Regulatory T Cell Function in Granulomatosis With Polyangiitis.JPEG by Gerjan J. Dekkema (7375049)

“…Overexpression of miR-142-3p significantly decreased cAMP levels (p = 0.02) and tended to decrease the mRNA levels of a predicted target gene, adenylate cyclase 9 (ADCY9; p = 0.06). …”

Table_1_Increased miR-142-3p Expression Might Explain Reduced Regulatory T Cell Function in Granulomatosis With Polyangiitis.pdf by Gerjan J. Dekkema (7375049)

“…Overexpression of miR-142-3p significantly decreased cAMP levels (p = 0.02) and tended to decrease the mRNA levels of a predicted target gene, adenylate cyclase 9 (ADCY9; p = 0.06). …”

Spatio-temporal changes in expression of pluripotency markers and self-organization of stem cell-derived aggregates in 3D culture. by Rachel E. DeJonge (3109986)

“…<p>(A-D) Expression of the pluripotency marker Nanog decreases as vesicles mature between differentiation days 5–8. …”

Cell elongation, <i>ϵ</i>_elong (left axis), and CMI (right axis) versus the cell centroid translocation in the presence of electotaxis as well as mechanotaxis. by Seyed Jamaleddin Mousavi (714603)

“…<p>a- <i>E</i> = 10 mV/mm and b- <i>E</i> = 100 mV/mm. …”

PKC translocation in response to PMA and secretagogues. by Oliver May (538881)

“…<p>PKC membrane expression as assessed by surface biotinylation and probing with a general PKC antibody significantly increased after exposure to PMA (100 nM), forskolin (10⁻⁵ M), or carbachol (10⁻⁴ M, 10 min each), which was paralleled by a decrease in cytosolic PKC expression [ODI: optical density integrated; *:p<0.05 vs. unstimulated, n =  6 preparations from separate mice in each group, ANOVA for correlated samples followed by Tukey's HSD (Tukey's honestly significant difference test), values expressed as % of the unstimulated control for cytosol and membrane, respectively].…”

Variance of the medians of <i>p</i>_<i>m</i>/<i>p</i>_<i>s</i> with respect to the level of popularity of messages. by Cangqi Zhou (813368)

“…The medians of the ratios, which are 4.654, 4.362, 3.898 and 3.100 respectively, decrease slightly as the level of popularity increases.…”

National trends in age-standardized mortality attributable to hypertension in Peru by Percy Herrera-Añazco (4259824)

“…Results: The age-standardized HTN mortality per 100,000 inhabitants decreased from 14.43 for the 2005 to 2010 period to 11.12 for the 2011 to 2016 period. …”

National trends in age-standardized mortality attributable to hypertension in Peru by Percy Herrera-Añazco (4259824)

“…Results: The age-standardized HTN mortality per 100,000 inhabitants decreased from 14.43 for the 2005 to 2010 period to 11.12 for the 2011 to 2016 period. …”