Imported malaria in the UK, 2005 to 2016: Estimates from primary care electronic health records by Hamad Bastaki (5881133)

“…The incidence of recorded malaria followed a decreasing trend dropping from a rate of 3.33 in 2005 to 1.36 cases per 100,000 person years at risk in 2016. …”

Osteopontin ELISA. by M. L. Arffa (3390416)

“…Treatment with 2μg/ml of EGCG caused a significant ~2.5-fold decrease in OPN protein levels compared with no treatment control, and only inhibition of miR-221 abrogated these effects (7.96 ng/ml ± 0.03 ng/ml vs 20.17ng/ml ± 0.32ng/ml; 19.76 ng/ml ± 0.95 ng/ml; all <i>P</i><0.01). …”

Data Sheet 2_Altered gut microbial networks and metabolic pathways in multiple system atrophy: a comparative 16S rRNA study.csv by Po-Chun Liu (676035)

“…The random forest classifiers effectively differentiated between MSA and PD, achieving high AUCs (0.75–0.78) in 5-fold cross-validation. A significant positive interbacterial interaction between Ruminococcus gnavus group and Erysipelatoclostridium was uniquely observed in MSA patients. …”

Representation of the GE356 Fab crystal structure and paratope mapping analysis. by Marjon Navis (92808)

“…The color-coding reflects fold-decrease in binding or of neutralization activity as compared to WT, in red (>50× WT), dark orange (20–50× WT), light orange (10–20× WT) and yellow (5–10× WT). …”

Increased Oxidative Damage in Carriers of the Germline <em>TP53</em> p.R337H Mutation by Gabriel S. Macedo (128234)

“…Mutation carriers also showed a four-fold increase in plasma malondialdehyde levels, indicating increased lipid peroxidation (NC = 40.20±0.71, C = 160.5±0.88, <em>P</em><0.0001). …”

Curcumin suppresses constitutively activated NFκB activity, down regulates Bcl-_xl and causes mitochondrial membrane depolarization in AtT20 cells. by Madhavi Latha Yadav Bangaru (365520)

“…The dot plots show that in vehicle and 5 µM curcumin treated cells, the % of cells emitting green fluorescence is low, and is indicative of basal apoptosis. …”

Renal phenotype of male Akita mice by genetic background. by Jae-Hyung Chang (327325)

“…<p>NR: not reported, ND: Not detected,</p>*<p>Compared to strain matched non-diabetic controls,</p>†<p>Animal models of diabetic complications consortium (ADMCC) criteria: >10-fold increase in albuminuria, >50% decrease in GFR over the lifetime of the animal, Advanced mesangial expansion, Arteriolar hylanosis, >50% increase in GBM thickness, Tubulointerstitial fibrosis,</p>**<p>variable (see text for discussion),</p>‡<p>Increased BUN at 30–40 weeks of age, References: <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0033942#pone.0033942-Breyer1" target="_blank">[3]</a>, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0033942#pone.0033942-Gurley1" target="_blank">[4]</a>, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0033942#pone.0033942-Gurley2" target="_blank">[5]</a>, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0033942#pone.0033942-Susztak1" target="_blank">[13]</a>, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0033942#pone.0033942-Brosius1" target="_blank">[30]</a>, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0033942#pone.0033942-Hong1" target="_blank">[35]</a>, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0033942#pone.0033942-Haseyama1" target="_blank">[48]</a>.…”

MSL-distance associated with distinct germline regulation and ancestral expression patterns. by Kevin H-C. Wei (7879079)

“…The fold changes in X:A ratio between testes cell stages are depicted in log scale for the different gene categories, with greater and less than 0 values representing increase and decrease in expression. …”

Regulation of Lipid Metabolism by Dicer Revealed through SILAC Mice by Tai-Chung Huang (841150)

“…We identified 646 proteins, of which 80 were up-regulated >2-fold and 75 were down-regulated. Consistent with the accumulation of lipids, Dicer disruption caused a marked decrease of microsomal triglyceride transfer protein, long-chain fatty acyl-CoA ligase 5, fatty acid binding protein, and very-long-chain fatty acyl-CoA dehydrogenase, among others. …”

Data Sheet 1_Perfusion process with tangential flow filtration for oncolytic VSV-GP production.docx by Orsolya Hamusics (21449015)

“…By optimizing the perfusion process, the titer reached up to 5.1 × 10¹⁰ TCID₅₀ mL^-1, which is 17-fold higher than in batch cultivation. …”

The structure of spontaneous locomotion in zebrafish larvae and mice during the active phase of the circadian cycle (light for zebrafish larvae, dark for mice). by Stefan Spulber (148803)

“…Zebrafish larvae exposed to 1 mg/L PFOS have a hyperactive phenotype characterized by a 2.5 fold higher distance swum during spontaneous bouts of activity. …”

Image_1_NTNG1 Modulates Cisplatin Resistance in Epithelial Ovarian Cancer Cells via the GAS6/AXL/Akt Pathway.pdf by Shanyu Fang (11058009)

“…Here, clinical data showed that the level of netrin-G1 (NTNG1) in cisplatin-resistant cancer was higher than that in cisplatin-sensitive cancer (2.2-fold, p = 0.005); patients with a high NTNG1 level in cancer tissues had shorter progression-free survival (11.0 vs. 25.0 months, p = 0.010) and platinum-free interval (5.0 vs. 20.0 months, p = 0.021) compared with patients with a low level. …”

Salinity induces unique changes in lipid classes and fatty acids of the estuarine haptophyte <i>Diacronema vlkianum</i> by José-Pedro Cañavate (11771443)

“…Hypersalinity caused a slight, although significant, sulpholipid decrease and a 4-fold increase in phosphatidylglycerol, suggesting a key role for this phospholipid in salt tolerance. …”

Data Sheet 3_Altered gut microbial networks and metabolic pathways in multiple system atrophy: a comparative 16S rRNA study.csv by Po-Chun Liu (676035)

“…The random forest classifiers effectively differentiated between MSA and PD, achieving high AUCs (0.75–0.78) in 5-fold cross-validation. A significant positive interbacterial interaction between Ruminococcus gnavus group and Erysipelatoclostridium was uniquely observed in MSA patients. …”

Jak2 is essential for DC development and maturation. by Jixin Zhong (115042)

“…Bone marrow cells (1×10⁷) were used to generate BMDCs using GM-CSF (10 ng/ml) and IL-4 (5 ng/ml) as described. Bone marrow cells deficient for Jak2 showed 1.3-fold decrease of BMDC yield. …”

Regulation of Lipid Metabolism by Dicer Revealed through SILAC Mice by Tai-Chung Huang (841150)

“…We identified 646 proteins, of which 80 were up-regulated >2-fold and 75 were down-regulated. Consistent with the accumulation of lipids, Dicer disruption caused a marked decrease of microsomal triglyceride transfer protein, long-chain fatty acyl-CoA ligase 5, fatty acid binding protein, and very-long-chain fatty acyl-CoA dehydrogenase, among others. …”

Extensive DNA End Processing by Exo1 and Sgs1 Inhibits Break-Induced Replication by Vanessa A. Marrero (245931)

“…However, in the <em>exo1Δ sgs1Δ</em> mutant, which is defective in the 5′-3′ resection of DSBs, the frequency of BIR was increased by 39-fold. …”

Supplementary Material for: Protective effects of Xanthohumol against diabetic nephropathy in a mouse model by Li F. (3206265)

“…Introduction: Diabetic nephropathy (DN) is a long-term loss of renal function occurring in the diabetic patients, leading to 5 million deaths in 2015, and this number is dramatically growing annually. …”

Datasheet1_Remotely detuned receiver coil for high-resolution interventional cardiac magnetic resonance imaging.pdf by Sina Marhabaie (8697576)

“…Taking advantage of the increase of SNR at its vicinity (up to 35 fold compared to conventional receiver coils), real-time MR-temperature imaging can reach an uncertainty below 0.1°C at the submillimetric spatial resolution. …”

DataSheet_1_Deep mowing rather than fire restrains grassland Miscanthus growth via affecting soil nutrient loss and microbial community redistribution.docx by Zhuxin Mao (12578495)

“…After harvest, deep mowing induced the greatest effect on biomass among all treatments, as it induced a 5.2-fold decrease in dry biomass relative to the control. …”