Image_2_A Novel Mechanism Regulating Dopamine Receptor Type 2 Signal Transduction in Pituitary Tumoral Cells: The Role of cAMP/PKA-Induced Filamin A Phosphorylation.jpeg by Federica Mangili (10146332)

“…Accordingly, S2152D FLNA expression abolished the expected ability of BIM53097 to increase or decrease, in MMQ and in AtT20 respectively, ERK phosphorylation, an effect that was maintained in S2152A FLNA expressing cells (+1.8 ± 0.65-fold, p < 0.05 in MMQ; -55 ± 13%, p < 0.01 in AtT-20). …”

Purification and Characterization of the Fe^II- and α-Ketoglutarate-Dependent Xanthine Hydroxylase from <i>Aspergillus nidulans</i>^† by Gabriela M. Montero-Morán (2493271)

“…The αKG cosubstrate can be substituted with α-ketoadipate (9-fold decrease in <i>k</i>_cat and 5-fold increase in the <i>K</i>_m compared to those of the normal α-keto acid), while the αKG analogue <i>N</i>-oxalylglycine is a competitive inhibitor (<i>K</i>_i = 0.12 μM). …”

Structure–Kinetics Correlations in Isostructural Crystals of α‑(<i>ortho</i>-Tolyl)-acetophenones: Pinning Down Electronic Effects Using Laser-Flash Photolysis in the Solid State... by Anoklase J.-L. Ayitou (1906648)

“…Notably, the rate for δ-hydrogen atom transfer of <b>1a</b> (2.7 × 10⁷ s^–1) in the crystalline phase is 18-fold larger than that of <b>1b</b> (1.5 × 10⁶ s^–1). …”

Image_1_Declines and Resilience of Communities of Leaf Chewing Insects on Missouri Oaks Following Spring Frost and Summer Drought.JPEG by Robert J. Marquis (2903021)

“…We present evidence that mid spring frosts and summer drought negatively affect the community of insects found on Missouri oaks (Quercus alba and Q. velutina), amounting to a 23–186 fold decrease depending on the oak species, insect body size and feeding guild, and the specific weather event. …”

Inhibition of Pig Phosphoenolpyruvate Carboxykinase Isoenzymes by 3-Mercaptopicolinic Acid and Novel Inhibitors by Jorge Hidalgo (145178)

“…Its inhibition patterns were the same for both isoenzymes: a three-fold decrease of the K_i values for GTP in 139Met and 139Leu (273 and 873 μM, respectively). …”

Data. by Nataly Carolina Mier (18764790)

“…Reverse transcription-quantitative polymerase chain reaction of the fraction of unspliced genomes in human embryonic kidney 293T cells increased up to 31% upon the indole’s treatment at 2.5 uM. Corresponding yield of infectious lentiviral vectors decreased up to 4.5-fold in a cell transduction assay. …”

Altering Pyrroloquinoline Quinone Nutritional Status Modulates Mitochondrial, Lipid, and Energy Metabolism in Rats by Kathryn Bauerly (213012)

“…Moreover, PQQ administration (i.p. at 4.5 mg/kg BW for 3 days) resulted in a greater than 2-fold decrease in plasma triglycerides during a 6-hour fast than saline administration in a rat model of type 2 diabetes. …”

Image_1_Declines and Resilience of Communities of Leaf Chewing Insects on Missouri Oaks Following Spring Frost and Summer Drought.JPEG by Robert J. Marquis (2903021)

“…We present evidence that mid spring frosts and summer drought negatively affect the community of insects found on Missouri oaks (Quercus alba and Q. velutina), amounting to a 23–186 fold decrease depending on the oak species, insect body size and feeding guild, and the specific weather event. …”

Analysis of the MMS RIT-seq screen. by Jennifer A. Stortz (4268842)

“…</b> Scatter plots showing the ratio of mapped RNAi target-specific reads for every gene (grey dots) in the RNAi-induced, MMS-treated population relative to the RNAi-induced, untreated population (MMS+/MMS-); gene location within the 11 megabase chromosomes is shown and dotted lines indicate 2-fold increase and decrease in MMS+/MMS- ratio. Genes are highlighted with roles in (A) homologous recombination (HR, red), mismatch repair (MMR, blue) and nucleotide excision repair (NER, green), or in (B) intraflagellar transport (IFT, red), mitochondrial replication (Mito rep, blue) and encoding histones (green). …”

Structure–Kinetics Correlations in Isostructural Crystals of α‑(<i>ortho</i>-Tolyl)-acetophenones: Pinning Down Electronic Effects Using Laser-Flash Photolysis in the Solid State... by Anoklase J.-L. Ayitou (1906648)

“…Notably, the rate for δ-hydrogen atom transfer of <b>1a</b> (2.7 × 10⁷ s^–1) in the crystalline phase is 18-fold larger than that of <b>1b</b> (1.5 × 10⁶ s^–1). …”

Combined Delivery of Paclitaxel and Tanespimycin via Micellar Nanocarriers: Pharmacokinetics, Efficacy and Metabolomic Analysis by Usha Katragadda (386668)

“…Compared with the free drugs at equivalent doses, intravenous administration of paclitaxel/17-AAG-loaded micelles led to 3.5- and 1.7-fold increase in the tumor concentrations of paclitaxel and 17-AAG, respectively, without significant altering drug levels in normal organs. …”

Engineering <i>Trichoderma reesei</i> for the hyperproduction of cellulose induced protein 1 (Cip1) on a sophorose-containing inducer to efficiently saccharify alkali-pretreated co... by Jianghong Li (4221922)

“…For <i>T. reesei</i> OE-cip1-1 and OE-cip1-2, the hydrolysis efficiency increased by 25.0 and 28.6% with a solid loading of 5% at 2 h, respectively. Simultaneously, 85.5 and 85.2 g/L glucose were released using a cellulase cocktail at high solid loading (20%), and these glucose release rates were significantly greater than that of <i>T. reesei</i> Rut C30 cellulase (77.4 g/L) at 120 h. …”

Changes in the spectral power of LFP recorded during animals' BSR. by Germán Vega-Flores (664425)

“…In window C, the less-preferred frequencies of reward (20 Hz, 8 Hz) did not induce changes in gamma and theta bands as the preferred frequency (100 Hz) did. The stimulation with 100 Hz as reward was associated with a decrease in the gamma band and an increase in the theta in comparison with both 20 Hz and 8 Hz (n = 9 animals, 20–30 sessions). …”

<i>D</i>α<i>7</i> mediates nicotine-induced mortality, developmental delay and acute nicotine and ethanol sensitivity. by Norma Andrea Velazquez-Ulloa (4023128)

“…(C) EY5 flies reared on 0.1mg/ml nicotine food (light green line) had decreased sensitivity to the acute effects of nicotine on a negative geotaxis test. …”

Effect of level of relative humidity on fungi and germination capacity of paddy (oryza sativa l.) Grains in egypt by Mazen, M.B. [محمد بهي الدين مازن]

“…At all levels, except at ~ 0%, of relative humidity the germination capacity of grain decreased slowly or rapidly with the increase of the storage period and the rate of decrease was enhanced with the rise of relative humidity which increased the moisture contents of grains, and complete mortality (100%) was recorded at 92% r.h. after 4 months and at 100% after 3 months, when the moisture contents of paddy grains rose to 21.6%'and 22.6% respectively.…”
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Data Sheet 1_Role of crevice size induced microenvironment variation within the gap in initiating crevice corrosion of 201 stainless steel.docx by Hao-Jing Ge (20573270)

“…<p>The effects of the real-time changes in the microenvironment within the crevice caused by the change in crevice size on the induction of crevice corrosion of 201 stainless steel (201-SS) in 1 M (pH = 4.00) NaCl solution were evaluated using conventional methods and scanning electrochemical microscopy (SECM) containing potentiometric probes. Results show that a decrease in pH and an increase in the Cl⁻ concentration within the gap are the pivotal determinants of crevice corrosion initiation. …”

<i>Tbca</i>16 knockdown increases the steady-state levels of <i>Tbca</i>13 RNA in GC-2spd(ts)-spermatocyte mouse cell line. by Sofia Nolasco (144740)

“…Normalized cDNA is expressed as a percentage of maximal value (100%). *p<0,05 compared with control. …”

Temporal analysis of the inclusion of Physical Education Professionals and Residents in the Brazilian Unified Health System (SUS) from 2009 to 2021 by Leonardo Araújo Vieira (14728266)

“…An increase of 476.01% in the number of PEFs and 10,366.67% among residents was revealed. The PEF rate per 100,000 inhabitants increased by 13.7% per year from 2009 to 2021, with an increase of 28.1% between 2009 and 2014 and 7.8% between 2014 and 2019, and a decrease of 3.4% between 2019 and 2021. …”

Decline in tuberculosis (TB) burden in children and adolescents in the Tibetan boarding schools in India from 2017 through 2019. by Kunchok Dorjee (4541518)

“…(B) Decrease in annual prevalence of TB infection. *Incidence of annual TB disease represents the proportion of new episodes of TB cases per 100,000 students per year among all students enrolled in the schools (<a href="http://www.plosmedicine.org/article/info:doi/10.1371/journal.pmed.1003502#pmed.1003502.t005" target="_blank">Table 5</a>). …”

Acute Toxicity of Silver Free and Encapsulated in Nanosized Zeolite for Eukaryotic Cells by Clément Anfray (3923939)

“…Cells were exposed to silver-containing zeolites (50, 100, and 400 μg/mL) for 24 and 48 h. After exposure to Ag⁺-EMT (50 μg/mL) for 24 h, a loss in cell viability independent of the cell type was observed, ranging from −34.37 ± 23.90% for astrocytes to −99.5 ± 0.24% for U87-MG cells. …”